Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

5420

Name

PODXL

Synonymous

podocalyxin-like;PODXL;podocalyxin-like

Definition

GCTM-2 antigen|podocalyxin|podocalyxin-like protein 1

Position

7q32-q33

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.834G>T; p.Q278H; 7:131509554-131509554

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.462T>C; p.D154D; 7:131511072-131511072

 livercarcinomaSubstitution - coding silent

c.846G>C; p.Q282H; 7:131509542-131509542

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.846G>C; p.Q282H; 7:131509542-131509542

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.802+2T>C; p.?; 7:131510234-131510234

 prostatecarcinoma; adenocarcinomaUnknown

c.302G>T; p.G101V; 7:131511232-131511232

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.158T>C; p.V53A; 7:131511376-131511376

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1309G>A; p.E437K; 7:131506262-131506262

 skinmalignant_melanomaSubstitution - Missense

c.1426G>A; p.V476M; 7:131505921-131505921

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.34C>T; p.L12L; 7:131556326-131556326

 thyroidother; neoplasmSubstitution - coding silent

c.351T>C; p.T117T; 7:131511183-131511183

 livercarcinomaSubstitution - coding silent

c.376A>G; p.T126A; 7:131511158-131511158

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.376A>G; p.T126A; 7:131511158-131511158

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.522G>A; p.K174K; 7:131511012-131511012

 skinmalignant_melanomaSubstitution - coding silent

c.678C>T; p.F226F; 7:131510856-131510856

 oesophaguscarcinomaSubstitution - coding silent

c.1483C>T; p.R495W; 7:131504505-131504505

 pancreasNSSubstitution - Missense

c.1483C>T; p.R495W; 7:131504505-131504505

 pancreascarcinomaSubstitution - Missense

c.950G>A; p.S317N; 7:131509438-131509438

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1341C>A; p.D447E; 7:131506006-131506006

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1555_1556insACCT; p.S519fs*4; 7:131504432-131504433

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaInsertion - Frameshift

c.170C>T; p.A57V; 7:131511364-131511364

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.487_488insC; p.S163fs*12; 7:131511046-131511047

 central_nervous_system; brainglioma; astrocytoma_Grade_IVInsertion - Frameshift

c.879G>T; p.Q293H; 7:131509509-131509509

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.879G>T; p.Q293H; 7:131509509-131509509

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.879G>T; p.Q293H; 7:131509509-131509509

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.665C>A; p.P222H; 7:131510869-131510869

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.311A>G; p.N104S; 7:131511223-131511223

 skinmalignant_melanomaSubstitution - Missense

c.570A>T; p.R190R; 7:131510964-131510964

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1295G>A; p.W432*; 7:131506276-131506276

 oesophaguscarcinoma; adenocarcinomaSubstitution - Nonsense

c.217G>A; p.E73K; 7:131511317-131511317

 skinmalignant_melanomaSubstitution - Missense

c.199C>A; p.P67T; 7:131511335-131511335

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.217G>A; p.E73K; 7:131511317-131511317

 skinmalignant_melanomaSubstitution - Missense

c.896C>T; p.T299M; 7:131509492-131509492

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.1410A>G; p.A470A; 7:131505937-131505937

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.1410A>G; p.A470A; 7:131505937-131505937

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.140C>T; p.P47L; 7:131511394-131511394

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1527C>T; p.D509D; 7:131504461-131504461

 thyroidcarcinoma; anaplastic_carcinomaSubstitution - coding silent

c.645T>C; p.S215S; 7:131510889-131510889

 skinmalignant_melanomaSubstitution - coding silent

c.584C>T; p.T195M; 7:131510950-131510950

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.584C>T; p.T195M; 7:131510950-131510950

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.361G>A; p.E121K; 7:131511173-131511173

 skinmalignant_melanomaSubstitution - Missense

c.584C>T; p.T195M; 7:131510950-131510950

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.480delG; p.S162fs*5; 7:131511054-131511054

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.480delG; p.S162fs*5; 7:131511054-131511054

 skinmalignant_melanomaDeletion - Frameshift

c.64_65insCGTCGC; p.S31_Q32insPS; 7:131556295-131556296

 soft_tissue; striated_musclerhabdomyosarcomaInsertion - In frame

c.1370G>A; p.R457H; 7:131505977-131505977

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1480C>T; p.Q494*; 7:131504508-131504508

 breastcarcinoma; ductal_carcinomaSubstitution - Nonsense

c.1481A>G; p.Q494R; 7:131504507-131504507

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1481A>G; p.Q494R; 7:131504507-131504507

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1516G>A; p.G506S; 7:131504472-131504472

 skinmalignant_melanomaSubstitution - Missense

c.1342C>A; p.Q448K; 7:131506005-131506005

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1364A>G; p.E455G; 7:131505983-131505983

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1570G>A; p.E524K; 7:131504418-131504418

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1128G>T; p.L376F; 7:131506700-131506700

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1674C>A; p.L558L; 7:131504314-131504314

 breastcarcinomaSubstitution - coding silent

c.344A>G; p.N115S; 7:131511190-131511190

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.706C>T; p.L236L; 7:131510828-131510828

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1572G>A; p.E524E; 7:131504416-131504416

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.827C>T; p.T276I; 7:131509561-131509561

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; myelofibrosisSubstitution - Missense

c.1412C>A; p.S471*; 7:131505935-131505935

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1184G>A; p.C395Y; 7:131506644-131506644

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1022G>A; p.W341*; 7:131509366-131509366

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.1591A>G; p.N531D; 7:131504397-131504397

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.544C>T; p.H182Y; 7:131510990-131510990

 breastcarcinomaSubstitution - Missense

c.675C>G; p.T225T; 7:131510859-131510859

 ovaryother; neoplasmSubstitution - coding silent

c.1287G>T; p.K429N; 7:131506284-131506284

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.685C>T; p.P229S; 7:131510849-131510849

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1198G>A; p.A400T; 7:131506630-131506630

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.977G>A; p.R326Q; 7:131509411-131509411

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.819G>A; p.S273S; 7:131509569-131509569

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.819G>A; p.S273S; 7:131509569-131509569

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.586C>A; p.H196N; 7:131510948-131510948

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.822A>G; p.Q274Q; 7:131509566-131509566

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.997C>T; p.P333S; 7:131509391-131509391

 skinmalignant_melanomaSubstitution - Missense

c.882G>C; p.E294D; 7:131509506-131509506

 NSNSSubstitution - Missense

c.1614G>A; p.W538*; 7:131504374-131504374

 skinmalignant_melanomaSubstitution - Nonsense

c.479G>A; p.G160E; 7:131511055-131511055

 skinmalignant_melanomaSubstitution - Missense

c.1234G>C; p.E412Q; 7:131506594-131506594

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.141G>A; p.P47P; 7:131511393-131511393

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.141G>A; p.P47P; 7:131511393-131511393

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1570_1572delGAG; p.E524delE; 7:131504416-131504418

 pancreascarcinoma; ductal_carcinomaDeletion - In frame

c.1129A>G; p.I377V; 7:131506699-131506699

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.101-1G>A; p.?; 7:131511434-131511434

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.1597G>A; p.E533K; 7:131504391-131504391

 skinmalignant_melanomaSubstitution - Missense

c.1597G>A; p.E533K; 7:131504391-131504391

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.547C>T; p.P183S; 7:131510987-131510987

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1607A>G; p.D536G; 7:131504381-131504381

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.945C>T; p.S315S; 7:131509443-131509443

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1645G>A; p.D549N; 7:131504343-131504343

 skinmalignant_melanomaSubstitution - Missense

c.1569G>T; p.Q523H; 7:131504419-131504419

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.244A>C; p.T82P; 7:131511290-131511290

 breastcarcinomaSubstitution - Missense

c.1430C>T; p.A477V; 7:131505917-131505917

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1430C>T; p.A477V; 7:131505917-131505917

 peritoneum; appendixother; pseudomyxoma_peritoneiSubstitution - Missense

c.1571A>G; p.E524G; 7:131504417-131504417

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.239C>T; p.A80V; 7:131511295-131511295

 skinmalignant_melanomaSubstitution - Missense

c.382delA; p.S128fs*39; 7:131511152-131511152

 stomachcarcinoma; intestinal_adenocarcinomaDeletion - Frameshift

c.136G>A; p.A46T; 7:131511398-131511398

 skin; trunkmalignant_melanomaSubstitution - Missense

c.1185C>T; p.C395C; 7:131506643-131506643

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.481A>G; p.K161E; 7:131511053-131511053

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.481A>G; p.K161E; 7:131511053-131511053

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1363G>A; p.E455K; 7:131505984-131505984

 oesophaguscarcinomaSubstitution - Missense

c.512C>T; p.T171I; 7:131511022-131511022

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.84_89delGTCGCC; p.P30_S31delPS; 7:131556271-131556276

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.84_89delGTCGCC; p.P30_S31delPS; 7:131556271-131556276

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaDeletion - In frame

c.84_89delGTCGCC; p.P30_S31delPS; 7:131556271-131556276

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaDeletion - In frame

c.84_89delGTCGCC; p.P30_S31delPS; 7:131556271-131556276

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaDeletion - In frame

c.84_89delGTCGCC; p.P30_S31delPS; 7:131556271-131556276

 prostatecarcinomaDeletion - In frame

c.84_89delGTCGCC; p.P30_S31delPS; 7:131556271-131556276

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaDeletion - In frame

c.84_89delGTCGCC; p.P30_S31delPS; 7:131556271-131556276

 prostatecarcinomaDeletion - In frame

c.84_89delGTCGCC; p.P30_S31delPS; 7:131556271-131556276

 kidneyWilms_tumourDeletion - In frame

c.84_85insGTCGCC; p.P28_S29insVA; 7:131556275-131556276

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.84_85insGTCGCC; p.P28_S29insVA; 7:131556275-131556276

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.84_85insGTCGCC; p.P28_S29insVA; 7:131556275-131556276

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.1074C>T; p.V358V; 7:131508978-131508978

 skinmalignant_melanomaSubstitution - coding silent

c.1074C>T; p.V358V; 7:131508978-131508978

 skinmalignant_melanomaSubstitution - coding silent

c.1166A>G; p.N389S; 7:131506662-131506662

 skin; armmalignant_melanomaSubstitution - Missense

c.1576_1578delAAG; p.K526delK; 7:131504410-131504412

 stomachadenocarcinomaDeletion - In frame

c.569G>A; p.R190Q; 7:131510965-131510965

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.988A>C; p.T330P; 7:131509400-131509400

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.776T>C; p.L259S; 7:131510262-131510262

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.320T>A; p.V107E; 7:131511214-131511214

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1308G>A; p.K436K; 7:131506263-131506263

 skinmalignant_melanomaSubstitution - coding silent

c.1627G>A; p.D543N; 7:131504361-131504361

 skinmalignant_melanomaSubstitution - Missense

c.222C>G; p.I74M; 7:131511312-131511312

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1570G>C; p.E524Q; 7:131504418-131504418

 breastcarcinoma; ductal_carcinomaSubstitution - Missense