Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

5325

Name

PLAGL1

Synonymous

pleiomorphic adenoma gene-like 1;PLAGL1;pleiomorphic adenoma gene-like 1

Definition

LOT-1|PLAG-like 1|lost on transformation 1|pleiomorphic adenoma-like protein 1|tumor suppressor ZAC|zinc finger protein PLAGL1

Position

6q24-q25

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.154C>T; p.H52Y; 6:143942662-143942662

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.644G>A; p.S215N; 6:143942172-143942172

 skinmalignant_melanomaSubstitution - Missense

c.342G>A; p.A114A; 6:143942474-143942474

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.1082T>C; p.L361P; 6:143941734-143941734

 prostatecarcinomaSubstitution - Missense

c.885G>A; p.P295P; 6:143941931-143941931

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1032G>T; p.K344N; 6:143941784-143941784

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1092G>A; p.E364E; 6:143941724-143941724

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.863C>T; p.S288L; 6:143941953-143941953

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.749A>G; p.N250S; 6:143942067-143942067

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.204G>A; p.E68E; 6:143942612-143942612

 skinmalignant_melanomaSubstitution - coding silent

c.1323delC; p.I442fs*>22; 6:143941493-143941493

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.762T>A; p.S254R; 6:143942054-143942054

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.395C>G; p.T132S; 6:143942421-143942421

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1167G>A; p.L389L; 6:143941649-143941649

 livercarcinomaSubstitution - coding silent

c.313G>T; p.G105C; 6:143942503-143942503

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1167G>A; p.L389L; 6:143941649-143941649

 livercarcinomaSubstitution - coding silent

c.112G>C; p.D38H; 6:143948025-143948025

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.507G>A; p.K169K; 6:143942309-143942309

 skinmalignant_melanomaSubstitution - coding silent

c.889C>G; p.P297A; 6:143941927-143941927

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.842C>G; p.S281C; 6:143941974-143941974

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.743C>T; p.A248V; 6:143942073-143942073

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1154G>A; p.G385D; 6:143941662-143941662

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.462G>T; p.K154N; 6:143942354-143942354

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1187A>G; p.N396S; 6:143941629-143941629

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1344T>C; p.A448A; 6:143941472-143941472

 thyroidother; neoplasmSubstitution - coding silent

c.396C>T; p.T132T; 6:143942420-143942420

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1089G>A; p.K363K; 6:143941727-143941727

 skinmalignant_melanomaSubstitution - coding silent

c.196C>A; p.H66N; 6:143942620-143942620

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1202G>A; p.S401N; 6:143941614-143941614

 skin; trunkmalignant_melanomaSubstitution - Missense

c.51G>T; p.E17D; 6:143948086-143948086

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.429G>A; p.A143A; 6:143942387-143942387

 livercarcinomaSubstitution - coding silent

c.429G>A; p.A143A; 6:143942387-143942387

 livercarcinomaSubstitution - coding silent

c.814G>A; p.A272T; 6:143942002-143942002

 pancreascarcinomaSubstitution - Missense

c.134C>T; p.S45F; 6:143948003-143948003

 skinmalignant_melanomaSubstitution - Missense

c.134C>T; p.S45F; 6:143948003-143948003

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.134C>T; p.S45F; 6:143948003-143948003

 livercarcinomaSubstitution - Missense

c.838G>A; p.E280K; 6:143941978-143941978

 skinmalignant_melanomaSubstitution - Missense

c.919T>G; p.S307A; 6:143941897-143941897

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1025C>T; p.P342L; 6:143941791-143941791

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.350G>C; p.S117T; 6:143942466-143942466

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.640G>A; p.E214K; 6:143942176-143942176

 skinmalignant_melanomaSubstitution - Missense

c.445A>G; p.S149G; 6:143942371-143942371

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.514C>T; p.R172*; 6:143942302-143942302

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1148T>C; p.L383P; 6:143941668-143941668

 skin; backmalignant_melanomaSubstitution - Missense

c.864G>T; p.S288S; 6:143941952-143941952

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.1211C>T; p.A404V; 6:143941605-143941605

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1343C>T; p.A448V; 6:143941473-143941473

 thyroidother; neoplasmSubstitution - Missense

c.1327C>T; p.P443S; 6:143941489-143941489

 skinmalignant_melanomaSubstitution - Missense

c.1322C>A; p.P441H; 6:143941494-143941494

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.747G>A; p.Q249Q; 6:143942069-143942069

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.747G>A; p.Q249Q; 6:143942069-143942069

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.781C>T; p.H261Y; 6:143942035-143942035

 skinmalignant_melanomaSubstitution - Missense

c.1342G>A; p.A448T; 6:143941474-143941474

 thyroidother; neoplasmSubstitution - Missense

c.758C>T; p.A253V; 6:143942058-143942058

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1355C>T; p.S452F; 6:143941461-143941461

 skinmalignant_melanomaSubstitution - Missense

c.973T>G; p.F325V; 6:143941843-143941843

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1340C>T; p.S447L; 6:143941476-143941476

 thyroidother; neoplasmSubstitution - Missense

c.59C>T; p.T20M; 6:143948078-143948078

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.584G>A; p.R195H; 6:143942232-143942232

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.457G>A; p.E153K; 6:143942359-143942359

 skinmalignant_melanomaSubstitution - Missense

c.1022C>G; p.S341*; 6:143941794-143941794

 prostateadenomaSubstitution - Nonsense

c.421G>T; p.A141S; 6:143942395-143942395

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1378C>T; p.H460Y; 6:143941438-143941438

 skinmalignant_melanomaSubstitution - Missense

c.1112A>C; p.N371T; 6:143941704-143941704

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.1369C>G; p.H457D; 6:143941447-143941447

 livercarcinomaSubstitution - Missense

c.1369C>G; p.H457D; 6:143941447-143941447

 livercarcinomaSubstitution - Missense

c.892C>T; p.L298F; 6:143941924-143941924

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.411C>T; p.D137D; 6:143942405-143942405

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.420delA; p.A141fs*71; 6:143942396-143942396

 oesophaguscarcinoma; adenocarcinomaDeletion - Frameshift

c.860C>T; p.P287L; 6:143941956-143941956

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.764G>A; p.S255N; 6:143942052-143942052

 skinmalignant_melanomaSubstitution - Missense

c.765C>T; p.S255S; 6:143942051-143942051

 oesophaguscarcinomaSubstitution - coding silent

c.985A>C; p.S329R; 6:143941831-143941831

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.218G>A; p.R73Q; 6:143942598-143942598

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1213C>A; p.L405M; 6:143941603-143941603

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1213C>A; p.L405M; 6:143941603-143941603

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.35C>T; p.T12M; 6:143948102-143948102

 stomachcarcinoma; adenocarcinomaSubstitution - Missense