Entrez Gene

Basic Information
Gene ID	5320
Name	PLA2G2A
Synonymous	phospholipase A2, group IIA (platelets, synovial fluid);PLA2G2A;phospholipase A2, group IIA (platelets, synovial fluid)
Definition	GIIC sPLA2\|NPS-PLA2\|group IIA phospholipase A2\|non-pancreatic secretory phospholipase A2\|phosphatidylcholine 2-acylhydrolase 2A\|phospholipase A2, membrane associated
Position	1p35
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.55C>T; p.H19Y; 1:19978510-19978510	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.55C>T; p.H19Y; 1:19978510-19978510	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.101G>A; p.G34E; 1:19978464-19978464	skin	malignant_melanoma	Substitution - Missense
c.385T>C; p.Y129H; 1:19975751-19975751	liver	carcinoma	Substitution - Missense
c.385T>C; p.Y129H; 1:19975751-19975751	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.112G>A; p.A38T; 1:19978453-19978453	liver	carcinoma	Substitution - Missense
c.148G>A; p.V50M; 1:19978417-19978417	skin	malignant_melanoma	Substitution - Missense
c.153T>G; p.G51G; 1:19978412-19978412	thyroid	other; neoplasm	Substitution - coding silent
c.138C>T; p.C46C; 1:19978427-19978427	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.34A>T; p.I12F; 1:19978740-19978740	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.118A>G; p.S40G; 1:19978447-19978447	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.374A>G; p.Y125C; 1:19975762-19975762	thyroid	carcinoma	Substitution - Missense
c.229C>T; p.R77C; 1:19978078-19978078	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.23C>T; p.A8V; 1:19978751-19978751	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.190T>C; p.C64R; 1:19978117-19978117	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.132C>T; p.Y44Y; 1:19978433-19978433	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.132C>T; p.Y44Y; 1:19978433-19978433	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma; large_cell	Substitution - coding silent
c.395A>G; p.Y132C; 1:19975741-19975741	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.184C>T; p.R62C; 1:19978381-19978381	skin	malignant_melanoma	Substitution - Missense
c.90G>C; p.K30N; 1:19978475-19978475	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.373T>A; p.Y125N; 1:19975763-19975763	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.311G>A; p.R104K; 1:19975825-19975825	urinary_tract; bladder	carcinoma	Substitution - Missense
c.421A>C; p.T141P; 1:19975715-19975715	breast	carcinoma	Substitution - Missense
c.187T>A; p.C63S; 1:19978120-19978120	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.272C>T; p.S91L; 1:19978035-19978035	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.327G>T; p.E109D; 1:19975809-19975809	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.290G>T; p.C97F; 1:19978017-19978017	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.413G>A; p.R138K; 1:19975723-19975723	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.279C>T; p.S93S; 1:19978028-19978028	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]