Entrez Gene

Basic Information
Gene ID	51754
Name	TMEM8B
Synonymous	transmembrane protein 8B;TMEM8B;transmembrane protein 8B
Definition	Protein NGX6\|nasopharyngeal carcinoma expressed 6\|nasopharyngeal carcinoma related protein\|nasopharyngeal carcinoma-associated gene 6 protein\|protein NAG-5
Position	9p13.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.450G>A; p.T150T; 9:35846334-35846334	oesophagus	carcinoma	Substitution - coding silent
c.618C>T; p.Y206Y; 9:35846589-35846589	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.105C>T; p.C35C; 9:35842543-35842543	liver	carcinoma	Substitution - coding silent
c.105C>T; p.C35C; 9:35842543-35842543	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.425G>A; p.R142K; 9:35846309-35846309	skin	malignant_melanoma	Substitution - Missense
c.825C>T; p.C275C; 9:35847001-35847001	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.132C>T; p.N44N; 9:35842570-35842570	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.539G>A; p.R180H; 9:35846510-35846510	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.278C>T; p.A93V; 9:35842716-35842716	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.662_671del10; p.T221fs*18; 9:35846838-35846847	liver	carcinoma	Deletion - Frameshift
c.496C>T; p.R166W; 9:35846380-35846380	prostate	adenoma	Substitution - Missense
c.176C>A; p.P59Q; 9:35842614-35842614	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.497G>A; p.R166Q; 9:35846381-35846381	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.811T>G; p.F271V; 9:35846987-35846987	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.611A>T; p.Y204F; 9:35846582-35846582	liver	carcinoma	Substitution - Missense
c.611A>T; p.Y204F; 9:35846582-35846582	liver	carcinoma	Substitution - Missense
c.764G>A; p.R255Q; 9:35846940-35846940	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.764G>A; p.R255Q; 9:35846940-35846940	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.54C>T; p.S18S; 9:35842492-35842492	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.50C>A; p.P17Q; 9:35842488-35842488	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.843A>T; p.L281F; 9:35847019-35847019	ovary	other; neoplasm	Substitution - Missense
c.139G>A; p.D47N; 9:35842577-35842577	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.593T>A; p.L198Q; 9:35846564-35846564	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.677C>T; p.A226V; 9:35846853-35846853	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.591G>C; p.K197N; 9:35846562-35846562	breast	carcinoma	Substitution - Missense
c.120G>A; p.P40P; 9:35842558-35842558	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.249C>T; p.G83G; 9:35842687-35842687	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.894G>A; p.T298T; 9:35847070-35847070	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.65C>A; p.P22H; 9:35842503-35842503	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.17C>A; p.S6Y; 9:35842455-35842455	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.517G>A; p.A173T; 9:35846488-35846488	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.763C>T; p.R255W; 9:35846939-35846939	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.328G>A; p.E110K; 9:35846023-35846023	breast	carcinoma	Substitution - Missense
c.377C>T; p.S126F; 9:35846261-35846261	skin	malignant_melanoma	Substitution - Missense
c.533G>A; p.R178Q; 9:35846504-35846504	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.306G>C; p.T102T; 9:35846001-35846001	thyroid	other; neoplasm	Substitution - coding silent
c.140A>G; p.D47G; 9:35842578-35842578	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]