Entrez Gene

Basic Information
Gene ID	5168
Name	ENPP2
Synonymous	ectonucleotide pyrophosphatase/phosphodiesterase 2;ENPP2;ectonucleotide pyrophosphatase/phosphodiesterase 2
Definition	E-NPP 2\|autotaxin-t\|ectonucleotide pyrophosphatase/phosphodiesterase family member 2\|extracellular lysophospholipase D\|phosphodiesterase I/nucleotide pyrophosphatase 2\|plasma lysophospholipase D
Position	8q24.1
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.2294G>A; p.W765*; 8:119564949-119564949	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2294G>A; p.W765*; 8:119564949-119564949	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1099C>T; p.H367Y; 8:119595876-119595876	breast	carcinoma	Substitution - Missense
c.353G>A; p.C118Y; 8:119621459-119621459	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.723T>G; p.T241T; 8:119616319-119616319	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.963C>T; p.F321F; 8:119600687-119600687	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1909C>T; p.R637W; 8:119580143-119580143	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1909C>T; p.R637W; 8:119580143-119580143	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1754A>G; p.H585R; 8:119582548-119582548	breast	carcinoma	Substitution - Missense
c.1336C>T; p.R446*; 8:119590532-119590532	skin	malignant_melanoma	Substitution - Nonsense
c.1336C>T; p.R446*; 8:119590532-119590532	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1336C>T; p.R446*; 8:119590532-119590532	breast	carcinoma	Substitution - Nonsense
c.2453C>G; p.T818S; 8:119562981-119562981	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2675G>A; p.R892Q; 8:119557594-119557594	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma; medullomyoblastoma	Substitution - Missense
c.2675G>A; p.R892Q; 8:119557594-119557594	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.2520T>C; p.P840P; 8:119562914-119562914	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1856G>T; p.C619F; 8:119582446-119582446	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2157T>A; p.C719*; 8:119569287-119569287	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1565T>A; p.F522Y; 8:119584008-119584008	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2520T>C; p.P840P; 8:119562914-119562914	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.870G>T; p.L290F; 8:119601426-119601426	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.776C>T; p.P259L; 8:119616266-119616266	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2263G>A; p.V755I; 8:119568199-119568199	ovary	other; neoplasm	Substitution - Missense
c.2515G>A; p.G839S; 8:119562919-119562919	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1306A>G; p.T436A; 8:119590562-119590562	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2525C>G; p.S842C; 8:119562909-119562909	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2525C>G; p.S842C; 8:119562909-119562909	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.664T>C; p.Y222H; 8:119616378-119616378	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1128+3A>T; p.?; 8:119595844-119595844	ovary	other; neoplasm	Unknown
c.1128+3A>T; p.?; 8:119595844-119595844	ovary	other; neoplasm	Unknown
c.1158A>C; p.K386N; 8:119593831-119593831	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.728A>G; p.H243R; 8:119616314-119616314	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1463C>T; p.A488V; 8:119586246-119586246	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1243G>A; p.E415K; 8:119590625-119590625	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1573G>A; p.G525R; 8:119584000-119584000	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2616G>A; p.M872I; 8:119557653-119557653	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.905C>T; p.S302L; 8:119600745-119600745	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.905C>T; p.S302L; 8:119600745-119600745	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.240T>G; p.C80W; 8:119626617-119626617	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1702C>A; p.L568I; 8:119582600-119582600	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2404G>A; p.E802K; 8:119564839-119564839	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.975G>T; p.E325D; 8:119596000-119596000	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1504C>T; p.R502C; 8:119586205-119586205	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1504C>T; p.R502C; 8:119586205-119586205	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1261A>G; p.R421G; 8:119590607-119590607	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2562C>A; p.N854K; 8:119562872-119562872	thyroid	carcinoma	Substitution - Missense
c.1677T>C; p.I559I; 8:119583739-119583739	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.377C>G; p.A126G; 8:119621435-119621435	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1529C>T; p.P510L; 8:119584044-119584044	skin	malignant_melanoma	Substitution - Missense
c.2168A>C; p.K723T; 8:119569276-119569276	breast	carcinoma	Substitution - Missense
c.1529C>T; p.P510L; 8:119584044-119584044	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1231G>A; p.D411N; 8:119593758-119593758	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.939C>A; p.F313L; 8:119600711-119600711	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.659G>A; p.G220E; 8:119616383-119616383	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.537G>T; p.M179I; 8:119617506-119617506	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.419-8C>T; p.?; 8:119619312-119619312	skin; head_neck	malignant_melanoma; superficial_spreading	Unknown
c.524G>A; p.R175H; 8:119617519-119617519	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.777G>A; p.P259P; 8:119616265-119616265	pancreas	carcinoma	Substitution - coding silent
c.2538C>T; p.F846F; 8:119562896-119562896	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.2615T>C; p.M872T; 8:119557654-119557654	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.2695C>T; p.P899S; 8:119557574-119557574	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1189C>G; p.Q397E; 8:119593800-119593800	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.766G>A; p.G256R; 8:119616276-119616276	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.614T>C; p.V205A; 8:119617207-119617207	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2300A>G; p.Y767C; 8:119564943-119564943	stomach	adenocarcinoma	Substitution - Missense
c.507C>A; p.F169L; 8:119617536-119617536	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2679G>C; p.K893N; 8:119557590-119557590	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1743A>T; p.G581G; 8:119582559-119582559	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.136G>A; p.V46M; 8:119638425-119638425	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1166G>A; p.G389E; 8:119593823-119593823	liver	carcinoma	Substitution - Missense
c.62G>A; p.G21E; 8:119638499-119638499	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.780A>G; p.L260L; 8:119607975-119607975	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.69T>C; p.N23N; 8:119638492-119638492	thyroid	carcinoma	Substitution - coding silent
c.1568delT; p.F523fs*19; 8:119584005-119584005	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1166G>A; p.G389E; 8:119593823-119593823	liver	carcinoma	Substitution - Missense
c.1740T>C; p.H580H; 8:119582562-119582562	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1740T>C; p.H580H; 8:119582562-119582562	thyroid	other; neoplasm	Substitution - coding silent
c.1417T>A; p.F473I; 8:119586292-119586292	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2382C>T; p.D794D; 8:119564861-119564861	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.152C>T; p.P51L; 8:119626705-119626705	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.283T>G; p.L95V; 8:119626574-119626574	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.302G>T; p.W101L; 8:119621510-119621510	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2117G>A; p.R706Q; 8:119569327-119569327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2634G>A; p.R878R; 8:119557635-119557635	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.970G>A; p.E324K; 8:119600680-119600680	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1611+2T>C; p.?; 8:119583960-119583960	stomach	carcinoma; adenocarcinoma	Unknown
c.2084C>A; p.S695Y; 8:119569360-119569360	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2352C>T; p.N784N; 8:119564891-119564891	NS	malignant_melanoma	Substitution - coding silent
c.1068G>A; p.K356K; 8:119595907-119595907	skin	malignant_melanoma	Substitution - coding silent
c.1070A>G; p.K357R; 8:119595905-119595905	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1070A>G; p.K357R; 8:119595905-119595905	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2147G>A; p.S716N; 8:119569297-119569297	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.491_492CT>TA; p.P164L; 8:119617551-119617552	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1369C>T; p.P457S; 8:119587070-119587070	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1924G>A; p.G642R; 8:119580128-119580128	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.241_242insT; p.K81fs*9; 8:119626615-119626616	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.2187C>T; p.S729S; 8:119569257-119569257	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.541A>T; p.K181*; 8:119617502-119617502	autonomic_ganglia	neuroblastoma	Substitution - Nonsense
c.2510G>A; p.C837Y; 8:119562924-119562924	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2275C>G; p.P759A; 8:119568187-119568187	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1562G>T; p.C521F; 8:119584011-119584011	breast	carcinoma	Substitution - Missense
c.2198T>C; p.L733P; 8:119569246-119569246	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.958C>A; p.P320T; 8:119600692-119600692	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.590C>T; p.T197I; 8:119617231-119617231	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2679G>A; p.K893K; 8:119557590-119557590	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1204delC; p.R402fs*24; 8:119593785-119593785	pleura	pulmonary_blastoma	Deletion - Frameshift
c.2679G>A; p.K893K; 8:119557590-119557590	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.419G>A; p.G140E; 8:119619304-119619304	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2589C>T; p.D863D; 8:119557680-119557680	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1152C>T; p.I384I; 8:119593837-119593837	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1228G>A; p.G410R; 8:119593761-119593761	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1537G>A; p.V513I; 8:119584036-119584036	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1109C>T; p.A370V; 8:119595866-119595866	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1109C>T; p.A370V; 8:119595866-119595866	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1545G>T; p.K515N; 8:119584028-119584028	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2373C>T; p.F791F; 8:119564870-119564870	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1642A>G; p.K548E; 8:119583774-119583774	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.113G>A; p.G38E; 8:119638448-119638448	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.328G>A; p.E110K; 8:119621484-119621484	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1259A>G; p.D420G; 8:119590609-119590609	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1622T>A; p.V541E; 8:119583794-119583794	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1117C>T; p.R373C; 8:119595858-119595858	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2247C>T; p.F749F; 8:119568215-119568215	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.451G>A; p.E151K; 8:119619272-119619272	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1124A>C; p.D375A; 8:119595851-119595851	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1723C>G; p.P575A; 8:119582579-119582579	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2444C>A; p.P815H; 8:119562990-119562990	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1117C>A; p.R373S; 8:119595858-119595858	central_nervous_system; brain	glioma	Substitution - Missense
c.562A>G; p.N188D; 8:119617481-119617481	liver	carcinoma	Substitution - Missense
c.968C>A; p.P323H; 8:119600682-119600682	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.156G>T; p.W52C; 8:119626701-119626701	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.487C>T; p.R163C; 8:119617556-119617556	skin; ankle	malignant_melanoma; acral_lentiginous	Substitution - Missense
c.487C>T; p.R163C; 8:119617556-119617556	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.487C>T; p.R163C; 8:119617556-119617556	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1957C>T; p.R653*; 8:119570821-119570821	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1957C>T; p.R653*; 8:119570821-119570821	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1530T>C; p.P510P; 8:119584043-119584043	central_nervous_system; brain	glioma	Substitution - coding silent
c.303G>A; p.W101*; 8:119621509-119621509	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1480G>C; p.E494Q; 8:119586229-119586229	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1118G>A; p.R373H; 8:119595857-119595857	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1033A>T; p.K345*; 8:119595942-119595942	skin	malignant_melanoma	Substitution - Nonsense
c.1118G>A; p.R373H; 8:119595857-119595857	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1932A>G; p.T644T; 8:119580120-119580120	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.900-4A>T; p.?; 8:119600754-119600754	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.1456C>T; p.H486Y; 8:119586253-119586253	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.900-4A>T; p.?; 8:119600754-119600754	liver	carcinoma	Unknown
c.2739C>T; p.S913S; 8:119557530-119557530	pancreas	carcinoma	Substitution - coding silent
c.1785C>T; p.T595T; 8:119582517-119582517	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1450C>T; p.R484C; 8:119586259-119586259	breast	carcinoma	Substitution - Missense
c.1237+2T>C; p.?; 8:119593750-119593750	liver	carcinoma	Unknown
c.1073G>T; p.R358I; 8:119595902-119595902	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1073G>T; p.R358I; 8:119595902-119595902	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.836T>C; p.V279A; 8:119601460-119601460	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1073G>T; p.R358I; 8:119595902-119595902	breast	carcinoma	Substitution - Missense
c.977G>A; p.S326N; 8:119595998-119595998	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.17C>T; p.S6L; 8:119638764-119638764	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.846C>T; p.H282H; 8:119601450-119601450	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.846C>T; p.H282H; 8:119601450-119601450	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1340C>T; p.S447F; 8:119590528-119590528	breast	carcinoma	Substitution - Missense
c.1133C>A; p.T378K; 8:119593856-119593856	pancreas	carcinoma	Substitution - Missense
c.2584G>A; p.E862K; 8:119557685-119557685	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1955G>T; p.G652V; 8:119570823-119570823	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1458C>G; p.H486Q; 8:119586251-119586251	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.880A>G; p.T294A; 8:119601416-119601416	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.343G>T; p.E115*; 8:119621469-119621469	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2605G>A; p.E869K; 8:119557664-119557664	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1131G>T; p.M377I; 8:119593858-119593858	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2288-1G>T; p.?; 8:119564956-119564956	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.733C>T; p.R245*; 8:119616309-119616309	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1025T>C; p.V342A; 8:119595950-119595950	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1831C>A; p.L611I; 8:119582471-119582471	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2325A>C; p.K775N; 8:119564918-119564918	pancreas	carcinoma	Substitution - Missense
c.2325A>C; p.K775N; 8:119564918-119564918	pancreas	carcinoma	Substitution - Missense
c.1063C>A; p.P355T; 8:119595912-119595912	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.601T>C; p.Y201H; 8:119617220-119617220	prostate	carcinoma	Substitution - Missense
c.2203C>G; p.P735A; 8:119569241-119569241	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2325A>C; p.K775N; 8:119564918-119564918	pancreas	carcinoma	Substitution - Missense
c.2161G>A; p.A721T; 8:119569283-119569283	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.887C>A; p.P296Q; 8:119601409-119601409	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2741A>G; p.E914G; 8:119557528-119557528	breast	carcinoma	Substitution - Missense
c.95G>A; p.R32Q; 8:119638466-119638466	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.95G>A; p.R32Q; 8:119638466-119638466	breast	carcinoma	Substitution - Missense
c.2103G>T; p.L701L; 8:119569341-119569341	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1517T>C; p.V506A; 8:119586192-119586192	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2116C>T; p.R706W; 8:119569328-119569328	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.774A>T; p.Q258H; 8:119616268-119616268	central_nervous_system; brain	glioma	Substitution - Missense
c.1076G>T; p.R359I; 8:119595899-119595899	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2129G>C; p.R710P; 8:119569315-119569315	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1717C>T; p.P573S; 8:119582585-119582585	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.777G>T; p.P259P; 8:119616265-119616265	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.846C>G; p.H282Q; 8:119601450-119601450	breast	carcinoma	Substitution - Missense
c.1324C>G; p.L442V; 8:119590544-119590544	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2465G>A; p.S822N; 8:119562969-119562969	thyroid	carcinoma	Substitution - Missense
c.277C>A; p.L93M; 8:119626580-119626580	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2162C>T; p.A721V; 8:119569282-119569282	skin; extremity	malignant_melanoma	Substitution - Missense
c.658G>A; p.G220R; 8:119616384-119616384	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.120G>A; p.E40E; 8:119638441-119638441	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1146G>C; p.R382S; 8:119593843-119593843	thyroid	carcinoma	Substitution - Missense
c.908T>C; p.V303A; 8:119600742-119600742	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1528C>T; p.P510S; 8:119584045-119584045	skin; trunk	malignant_melanoma	Substitution - Missense
c.744G>A; p.E248E; 8:119616298-119616298	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.2262G>T; p.M754I; 8:119568200-119568200	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2348T>G; p.V783G; 8:119564895-119564895	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1396-8T>C; p.?; 8:119586321-119586321	pancreas	carcinoid-endocrine_tumour	Unknown
c.2431G>A; p.G811S; 8:119563003-119563003	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.346A>C; p.N116H; 8:119621466-119621466	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1164G>T; p.V388V; 8:119593825-119593825	oesophagus	carcinoma	Substitution - coding silent
c.1300G>T; p.D434Y; 8:119590568-119590568	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2322G>T; p.K774N; 8:119564921-119564921	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.349G>T; p.A117S; 8:119621463-119621463	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.426G>A; p.S142S; 8:119619297-119619297	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.426G>A; p.S142S; 8:119619297-119619297	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1854C>A; p.G618G; 8:119582448-119582448	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.426G>A; p.S142S; 8:119619297-119619297	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.480-4T>G; p.?; 8:119617567-119617567	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1854C>A; p.G618G; 8:119582448-119582448	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2724G>A; p.L908L; 8:119557545-119557545	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1153G>A; p.D385N; 8:119593836-119593836	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1446C>G; p.P482P; 8:119586263-119586263	breast	carcinoma	Substitution - coding silent
c.1262G>T; p.R421I; 8:119590606-119590606	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2632A>C; p.R878R; 8:119557637-119557637	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2632A>C; p.R878R; 8:119557637-119557637	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.579G>T; p.R193S; 8:119617242-119617242	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2287+1delG; p.?; 8:119568174-119568174	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Unknown
c.2309_2310GG>AA; p.R770K; 8:119564933-119564934	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.847G>A; p.E283K; 8:119601449-119601449	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.630C>A; p.T210T; 8:119617191-119617191	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.606G>T; p.M202I; 8:119617215-119617215	breast	carcinoma	Substitution - Missense
c.2518C>A; p.P840T; 8:119562916-119562916	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1749G>A; p.L583L; 8:119582553-119582553	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1569C>T; p.F523F; 8:119584004-119584004	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2516G>T; p.G839V; 8:119562918-119562918	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2503G>A; p.D835N; 8:119562931-119562931	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1340C>A; p.S447Y; 8:119590528-119590528	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1331G>T; p.R444I; 8:119590537-119590537	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1331G>T; p.R444I; 8:119590537-119590537	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1964C>T; p.A655V; 8:119570814-119570814	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1973A>T; p.Y658F; 8:119570805-119570805	oesophagus	carcinoma	Substitution - Missense
c.294C>A; p.A98A; 8:119621518-119621518	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.2088C>T; p.S696S; 8:119569356-119569356	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.127C>T; p.P43S; 8:119638434-119638434	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.127C>T; p.P43S; 8:119638434-119638434	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.328G>T; p.E110*; 8:119621484-119621484	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1267G>C; p.E423Q; 8:119590601-119590601	breast	carcinoma	Substitution - Missense
c.82T>A; p.F28I; 8:119638479-119638479	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1762C>T; p.R588C; 8:119582540-119582540	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1071A>G; p.K357K; 8:119595904-119595904	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1539T>C; p.V513V; 8:119584034-119584034	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1539T>C; p.V513V; 8:119584034-119584034	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.391T>A; p.C131S; 8:119621421-119621421	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2287+1G>A; p.?; 8:119568174-119568174	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.795C>T; p.T265T; 8:119607960-119607960	skin	malignant_melanoma	Substitution - coding silent
c.2523C>G; p.L841L; 8:119562911-119562911	skin	malignant_melanoma	Substitution - coding silent
c.1737C>G; p.T579T; 8:119582565-119582565	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2563G>T; p.E855*; 8:119562871-119562871	prostate	carcinoma; adenocarcinoma	Substitution - Nonsense
c.285G>A; p.L95L; 8:119626572-119626572	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1028C>T; p.A343V; 8:119595947-119595947	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1886A>G; p.N629S; 8:119580166-119580166	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.630C>T; p.T210T; 8:119617191-119617191	skin	malignant_melanoma	Substitution - coding silent
c.1569C>A; p.F523L; 8:119584004-119584004	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.48C>A; p.F16L; 8:119638513-119638513	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2560A>G; p.N854D; 8:119562874-119562874	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2560A>G; p.N854D; 8:119562874-119562874	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2562C>T; p.N854N; 8:119562872-119562872	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2562C>T; p.N854N; 8:119562872-119562872	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2562C>T; p.N854N; 8:119562872-119562872	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1405C>A; p.P469T; 8:119586304-119586304	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]