Entrez Gene

Basic Information
Gene ID	4843
Name	NOS2
Synonymous	nitric oxide synthase 2, inducible;NOS2;nitric oxide synthase 2, inducible
Definition	NOS type II\|NOS, type II\|hepatocyte NOS\|inducible NO synthase\|inducible NOS\|nitric oxide synthase 2A (inducible, hepatocytes)\|nitric oxide synthase, inducible\|nitric oxide synthase, macrophage\|peptidyl-cysteine S-nitrosylase NOS2
Position	17q11.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.3181C>A; p.R1061R; 17:27759054-27759054	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.383G>C; p.G128A; 17:27787762-27787762	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3217C>A; p.H1073N; 17:27759018-27759018	thyroid	other; neoplasm	Substitution - Missense
c.2293C>A; p.L765M; 17:27765670-27765670	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.644G>A; p.R215H; 17:27782093-27782093	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2968C>A; p.R990S; 17:27760665-27760665	breast	carcinoma	Substitution - Missense
c.2035G>T; p.A679S; 17:27767837-27767837	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.722+3C>T; p.?; 17:27782012-27782012	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.2207G>T; p.R736M; 17:27766549-27766549	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2377G>A; p.D793N; 17:27765586-27765586	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3149G>A; p.G1050D; 17:27760040-27760040	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.319-1G>T; p.?; 17:27787827-27787827	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.958G>A; p.E320K; 17:27780813-27780813	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1656G>A; p.A552A; 17:27772356-27772356	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.958G>A; p.E320K; 17:27780813-27780813	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1656G>A; p.A552A; 17:27772356-27772356	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2735C>T; p.S912F; 17:27762863-27762863	skin	malignant_melanoma	Substitution - Missense
c.744C>T; p.P248P; 17:27781156-27781156	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.744C>T; p.P248P; 17:27781156-27781156	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3334G>C; p.D1112H; 17:27758901-27758901	breast	carcinoma	Substitution - Missense
c.2140G>A; p.D714N; 17:27767732-27767732	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1714A>G; p.M572V; 17:27771008-27771008	urinary_tract; bladder	carcinoma	Substitution - Missense
c.503C>A; p.A168E; 17:27783071-27783071	skin	malignant_melanoma	Substitution - Missense
c.922G>A; p.V308I; 17:27780849-27780849	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.736G>T; p.V246L; 17:27781164-27781164	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.924C>A; p.V308V; 17:27780847-27780847	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1954C>T; p.Q652*; 17:27769057-27769057	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.664G>A; p.E222K; 17:27782073-27782073	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.634T>G; p.F212V; 17:27782103-27782103	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3452C>T; p.S1151L; 17:27757256-27757256	skin	malignant_melanoma	Substitution - Missense
c.2347C>G; p.L783V; 17:27765616-27765616	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1906G>C; p.A636P; 17:27769105-27769105	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.170C>T; p.P57L; 17:27789629-27789629	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1823C>T; p.S608L; 17:27769571-27769571	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.690C>A; p.H230Q; 17:27782047-27782047	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1588C>T; p.R530C; 17:27772424-27772424	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2536C>A; p.L846M; 17:27764037-27764037	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2828T>C; p.V943A; 17:27761204-27761204	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.149G>A; p.S50N; 17:27789650-27789650	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2083C>A; p.P695T; 17:27767789-27767789	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2083C>T; p.P695S; 17:27767789-27767789	skin	malignant_melanoma	Substitution - Missense
c.1005-1G>A; p.?; 17:27779057-27779057	lung	carcinoma; adenocarcinoma	Unknown
c.3230G>A; p.G1077D; 17:27759005-27759005	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2306C>A; p.P769Q; 17:27765657-27765657	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.261delC; p.N89fs*6; 17:27788866-27788866	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.2904C>T; p.H968H; 17:27760729-27760729	breast	carcinoma	Substitution - coding silent
c.1344G>T; p.Q448H; 17:27774389-27774389	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.568A>C; p.T190P; 17:27783006-27783006	breast	carcinoma	Substitution - Missense
c.147C>T; p.L49L; 17:27789652-27789652	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2207G>C; p.R736T; 17:27766549-27766549	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.2207G>C; p.R736T; 17:27766549-27766549	soft_tissue; striated_muscle	rhabdomyosarcoma	Substitution - Missense
c.1459_1460CC>TT; p.P487F; 17:27774273-27774274	skin	malignant_melanoma	Substitution - Missense
c.906C>T; p.F302F; 17:27780865-27780865	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1429C>T; p.H477Y; 17:27774304-27774304	breast	carcinoma	Substitution - Missense
c.1824G>T; p.S608S; 17:27769570-27769570	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.902G>A; p.R301H; 17:27780869-27780869	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.235T>C; p.L79L; 17:27788892-27788892	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.426A>G; p.Q142Q; 17:27787719-27787719	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1043C>T; p.A348V; 17:27779018-27779018	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1672G>A; p.G558R; 17:27772340-27772340	breast	carcinoma	Substitution - Missense
c.2606G>T; p.S869I; 17:27762992-27762992	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2547_2548GG>AA; p.A850T; 17:27764025-27764026	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1104C>A; p.P368P; 17:27778957-27778957	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2035G>A; p.A679T; 17:27767837-27767837	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.72C>T; p.I24I; 17:27798738-27798738	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.957C>T; p.F319F; 17:27780814-27780814	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2575C>T; p.L859L; 17:27763998-27763998	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3258C>T; p.R1086R; 17:27758977-27758977	pancreas	carcinoma	Substitution - coding silent
c.1897C>T; p.R633W; 17:27769114-27769114	skin	malignant_melanoma	Substitution - Missense
c.2660C>A; p.P887Q; 17:27762938-27762938	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1449C>T; p.Y483Y; 17:27774284-27774284	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2969G>A; p.R990H; 17:27760664-27760664	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.425A>T; p.Q142L; 17:27787720-27787720	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.941G>A; p.R314H; 17:27780830-27780830	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.941G>A; p.R314H; 17:27780830-27780830	liver	carcinoma	Substitution - Missense
c.1075G>A; p.V359M; 17:27778986-27778986	skin	malignant_melanoma	Substitution - Missense
c.271G>A; p.G91S; 17:27788856-27788856	skin	malignant_melanoma	Substitution - Missense
c.1211A>G; p.H404R; 17:27778760-27778760	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1589G>A; p.R530H; 17:27772423-27772423	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.305A>G; p.H102R; 17:27788822-27788822	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1607G>A; p.R536Q; 17:27772405-27772405	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.468-3delC; p.?; 17:27783109-27783109	lung	carcinoma; small_cell_carcinoma	Unknown
c.2127delC; p.Y709fs*1; 17:27767745-27767745	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1607G>A; p.R536Q; 17:27772405-27772405	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1076T>G; p.V359G; 17:27778985-27778985	breast	carcinoma	Substitution - Missense
c.1209G>A; p.T403T; 17:27778762-27778762	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1488G>A; p.W496*; 17:27773232-27773232	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1488G>A; p.W496*; 17:27773232-27773232	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.994G>A; p.E332K; 17:27780777-27780777	central_nervous_system; brain	glioma	Substitution - Missense
c.3181C>T; p.R1061W; 17:27759054-27759054	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1371C>G; p.C457W; 17:27774362-27774362	skin	malignant_melanoma	Substitution - Missense
c.1319C>A; p.A440E; 17:27774414-27774414	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1353C>G; p.Y451*; 17:27774380-27774380	ovary	carcinoma; serous_carcinoma	Substitution - Nonsense
c.1704+1G>C; p.?; 17:27772307-27772307	lung	carcinoma; adenocarcinoma	Unknown
c.2757A>G; p.T919T; 17:27762841-27762841	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.487C>T; p.L163L; 17:27783087-27783087	skin; back	malignant_melanoma	Substitution - coding silent
c.596G>A; p.R199H; 17:27782978-27782978	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.96C>A; p.P32P; 17:27798714-27798714	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2693C>T; p.S898F; 17:27762905-27762905	skin	malignant_melanoma	Substitution - Missense
c.2693C>T; p.S898F; 17:27762905-27762905	skin	malignant_melanoma	Substitution - Missense
c.1295C>T; p.T432I; 17:27774438-27774438	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2358T>C; p.G786G; 17:27765605-27765605	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1326C>A; p.S442S; 17:27774407-27774407	large_intestine; rectum	NS	Substitution - coding silent
c.1948G>A; p.A650T; 17:27769063-27769063	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1948G>A; p.A650T; 17:27769063-27769063	stomach	adenocarcinoma	Substitution - Missense
c.1437G>T; p.E479D; 17:27774296-27774296	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2170C>A; p.L724I; 17:27766586-27766586	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2243C>T; p.S748F; 17:27766513-27766513	liver	carcinoma	Substitution - Missense
c.2243C>T; p.S748F; 17:27766513-27766513	liver	carcinoma	Substitution - Missense
c.727G>A; p.A243T; 17:27781173-27781173	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.636C>T; p.F212F; 17:27782101-27782101	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3160G>A; p.V1054I; 17:27759075-27759075	skin; abdomen	malignant_melanoma	Substitution - Missense
c.1204G>A; p.E402K; 17:27778767-27778767	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1315G>A; p.A439T; 17:27774418-27774418	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.797G>A; p.R266H; 17:27781103-27781103	liver	carcinoma	Substitution - Missense
c.797G>A; p.R266H; 17:27781103-27781103	liver	carcinoma	Substitution - Missense
c.2599G>A; p.E867K; 17:27762999-27762999	skin	malignant_melanoma	Substitution - Missense
c.2320G>A; p.G774R; 17:27765643-27765643	skin	malignant_melanoma	Substitution - Missense
c.753T>C; p.S251S; 17:27781147-27781147	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2336A>G; p.N779S; 17:27765627-27765627	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2015G>A; p.W672*; 17:27768996-27768996	lung	carcinoma; small_cell_carcinoma	Substitution - Nonsense
c.1804G>A; p.G602R; 17:27770918-27770918	urinary_tract; bladder	carcinoma	Substitution - Missense
c.320T>A; p.I107N; 17:27787825-27787825	liver	carcinoma	Substitution - Missense
c.1750C>T; p.R584W; 17:27770972-27770972	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2309G>A; p.G770E; 17:27765654-27765654	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1215G>A; p.K405K; 17:27778756-27778756	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.168C>T; p.S56S; 17:27789631-27789631	breast	carcinoma	Substitution - coding silent
c.1840G>A; p.E614K; 17:27769554-27769554	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.1083C>A; p.G361G; 17:27778978-27778978	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.3412_3414delAAG; p.K1138delK; 17:27757294-27757296	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - In frame
c.799T>A; p.Y267N; 17:27781101-27781101	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2272T>C; p.S758P; 17:27765691-27765691	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2546T>A; p.V849E; 17:27764027-27764027	bone; humerus	chondrosarcoma	Substitution - Missense
c.3364C>T; p.R1122C; 17:27757344-27757344	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1081G>A; p.G361S; 17:27778980-27778980	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3425C>T; p.A1142V; 17:27757283-27757283	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.448T>C; p.Y150H; 17:27787697-27787697	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.154C>T; p.Q52*; 17:27789645-27789645	central_nervous_system; brain	glioma	Substitution - Nonsense
c.735C>T; p.T245T; 17:27781165-27781165	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.858C>T; p.F286F; 17:27781042-27781042	skin	malignant_melanoma	Substitution - coding silent
c.1332G>T; p.M444I; 17:27774401-27774401	urinary_tract; bladder	carcinoma	Substitution - Missense
c.864+9C>A; p.?; 17:27781027-27781027	pancreas	carcinoma	Unknown
c.2428+9C>T; p.?; 17:27765526-27765526	ovary	other; neoplasm	Unknown
c.1383G>A; p.W461*; 17:27774350-27774350	skin	malignant_melanoma	Substitution - Nonsense
c.1959C>T; p.L653L; 17:27769052-27769052	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.249G>A; p.R83R; 17:27788878-27788878	skin	malignant_melanoma	Substitution - coding silent
c.3355-1G>T; p.?; 17:27757354-27757354	skin	malignant_melanoma	Unknown
c.3327G>A; p.Q1109Q; 17:27758908-27758908	skin	malignant_melanoma	Substitution - coding silent
c.1041C>T; p.Y347Y; 17:27779020-27779020	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2458C>G; p.P820A; 17:27764115-27764115	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.415C>A; p.L139I; 17:27787730-27787730	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2383C>T; p.P795S; 17:27765580-27765580	skin	malignant_melanoma	Substitution - Missense
c.245C>T; p.P82L; 17:27788882-27788882	skin	malignant_melanoma	Substitution - Missense
c.2040C>T; p.A680A; 17:27767832-27767832	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.197A>T; p.K66M; 17:27788930-27788930	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.497T>G; p.V166G; 17:27783077-27783077	breast	carcinoma	Substitution - Missense
c.1140C>T; p.V380V; 17:27778921-27778921	skin	malignant_melanoma	Substitution - coding silent
c.811C>T; p.Q271*; 17:27781089-27781089	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.195G>T; p.K65N; 17:27789604-27789604	prostate	adenoma	Substitution - Missense
c.2901C>T; p.F967F; 17:27760732-27760732	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.395A>G; p.K132R; 17:27787750-27787750	pancreas	carcinoma	Substitution - Missense
c.748C>T; p.R250W; 17:27781152-27781152	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1624C>A; p.L542I; 17:27772388-27772388	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.533C>T; p.T178I; 17:27783041-27783041	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.247C>T; p.R83W; 17:27788880-27788880	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2842C>T; p.L948F; 17:27761190-27761190	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1462T>G; p.F488V; 17:27774271-27774271	breast	carcinoma	Substitution - Missense
c.2663C>T; p.S888F; 17:27762935-27762935	skin	malignant_melanoma	Substitution - Missense
c.1844T>A; p.L615H; 17:27769550-27769550	liver	carcinoma	Substitution - Missense
c.725C>T; p.S242L; 17:27781175-27781175	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3342C>T; p.F1114F; 17:27758893-27758893	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.725C>T; p.S242L; 17:27781175-27781175	prostate	carcinoma	Substitution - Missense
c.433G>A; p.E145K; 17:27787712-27787712	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.433G>A; p.E145K; 17:27787712-27787712	breast	carcinoma	Substitution - Missense
c.2827G>A; p.V943I; 17:27761205-27761205	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.433G>A; p.E145K; 17:27787712-27787712	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.181G>A; p.V61M; 17:27789618-27789618	breast	carcinoma	Substitution - Missense
c.2134G>A; p.V712M; 17:27767738-27767738	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2218C>T; p.R740W; 17:27766538-27766538	skin	malignant_melanoma	Substitution - Missense
c.853G>A; p.E285K; 17:27781047-27781047	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.661C>T; p.R221W; 17:27782076-27782076	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.598T>C; p.C200R; 17:27782976-27782976	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3427G>A; p.V1143M; 17:27757281-27757281	kidney	other; neoplasm	Substitution - Missense
c.1329C>T; p.F443F; 17:27774404-27774404	breast	carcinoma	Substitution - coding silent
c.3071T>G; p.I1024S; 17:27760118-27760118	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3055C>A; p.P1019T; 17:27760134-27760134	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.183G>A; p.V61V; 17:27789616-27789616	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.183G>A; p.V61V; 17:27789616-27789616	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.915C>T; p.V305V; 17:27780856-27780856	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.767A>T; p.D256V; 17:27781133-27781133	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.200C>T; p.S67F; 17:27788927-27788927	skin	malignant_melanoma	Substitution - Missense
c.3050G>A; p.R1017H; 17:27760139-27760139	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2001C>T; p.D667D; 17:27769010-27769010	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3373G>A; p.E1125K; 17:27757335-27757335	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1360C>T; p.R454C; 17:27774373-27774373	skin	malignant_melanoma	Substitution - Missense
c.424C>G; p.Q142E; 17:27787721-27787721	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.874G>A; p.D292N; 17:27780897-27780897	breast	carcinoma	Substitution - Missense
c.1996G>A; p.E666K; 17:27769015-27769015	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.805_806delGG; p.G269fs*46; 17:27781094-27781095	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2148G>C; p.Q716H; 17:27767724-27767724	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.422C>T; p.P141L; 17:27787723-27787723	skin	malignant_melanoma	Substitution - Missense
c.1648T>C; p.S550P; 17:27772364-27772364	pancreas	carcinoma	Substitution - Missense
c.1155C>G; p.D385E; 17:27778906-27778906	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1777T>C; p.F593L; 17:27770945-27770945	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2273C>T; p.S758F; 17:27765690-27765690	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.1358C>A; p.S453Y; 17:27774375-27774375	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.543G>T; p.L181L; 17:27783031-27783031	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2237C>T; p.P746L; 17:27766519-27766519	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.176C>T; p.P59L; 17:27789623-27789623	skin	malignant_melanoma	Substitution - Missense
c.662G>A; p.R221Q; 17:27782075-27782075	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3386G>A; p.G1129D; 17:27757322-27757322	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1134C>T; p.I378I; 17:27778927-27778927	breast	carcinoma	Substitution - coding silent
c.1668C>A; p.D556E; 17:27772344-27772344	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.545C>T; p.T182M; 17:27783029-27783029	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.558C>T; p.L186L; 17:27783016-27783016	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1937C>T; p.S646F; 17:27769074-27769074	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3275C>T; p.A1092V; 17:27758960-27758960	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1878C>T; p.L626L; 17:27769133-27769133	skin	malignant_melanoma	Substitution - coding silent
c.762G>A; p.K254K; 17:27781138-27781138	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1540C>T; p.P514S; 17:27773180-27773180	large_intestine; colon	carcinoma	Substitution - Missense
c.445C>A; p.Q149K; 17:27787700-27787700	ovary	other; neoplasm	Substitution - Missense
c.2009G>A; p.R670H; 17:27769002-27769002	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.445C>A; p.Q149K; 17:27787700-27787700	ovary	other; neoplasm	Substitution - Missense
c.3164A>G; p.Y1055C; 17:27759071-27759071	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.584G>A; p.R195H; 17:27782990-27782990	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.584G>A; p.R195H; 17:27782990-27782990	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3265C>T; p.R1089W; 17:27758970-27758970	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.211C>T; p.L71L; 17:27788916-27788916	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1423G>T; p.V475L; 17:27774310-27774310	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1080C>T; p.G360G; 17:27778981-27778981	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1520G>T; p.R507I; 17:27773200-27773200	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2010C>T; p.R670R; 17:27769001-27769001	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2557G>A; p.E853K; 17:27764016-27764016	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3190C>A; p.L1064M; 17:27759045-27759045	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3271G>A; p.V1091M; 17:27758964-27758964	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.2959G>A; p.A987T; 17:27760674-27760674	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2800G>A; p.D934N; 17:27762798-27762798	liver	carcinoma	Substitution - Missense
c.1092C>T; p.F364F; 17:27778969-27778969	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.795C>T; p.I265I; 17:27781105-27781105	skin	malignant_melanoma	Substitution - coding silent

COSMIC somatic mutation [Top]