Entrez Gene

Basic Information
Gene ID	4804
Name	NGFR
Synonymous	nerve growth factor receptor;NGFR;nerve growth factor receptor
Definition	NGF receptor\|TNFR superfamily, member 16\|low affinity nerve growth factor receptor\|low affinity neurotrophin receptor p75NTR\|low-affinity nerve growth factor receptor\|p75 ICD\|tumor necrosis factor receptor superfamily member 16
Position	17q21-q22
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.327C>T; p.C109C; 17:49506417-49506417	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1184G>A; p.S395N; 17:49512909-49512909	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1001G>A; p.G334D; 17:49512726-49512726	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.827A>G; p.N276S; 17:49511897-49511897	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.655C>T; p.P219S; 17:49510498-49510498	skin	malignant_melanoma	Substitution - Missense
c.221C>G; p.S74C; 17:49506311-49506311	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.795C>T; p.G265G; 17:49510638-49510638	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.316G>A; p.V106M; 17:49506406-49506406	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.797T>G; p.L266R; 17:49510640-49510640	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.216G>A; p.T72T; 17:49506306-49506306	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.615G>A; p.S205S; 17:49510458-49510458	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.615G>A; p.S205S; 17:49510458-49510458	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1177C>A; p.Q393K; 17:49512902-49512902	urinary_tract; bladder	carcinoma	Substitution - Missense
c.605C>T; p.P202L; 17:49510448-49510448	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1053C>G; p.L351L; 17:49512778-49512778	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.410C>T; p.S137F; 17:49506500-49506500	skin	malignant_melanoma	Substitution - Missense
c.934C>T; p.Q312*; 17:49512004-49512004	breast	carcinoma	Substitution - Nonsense
c.24C>T; p.R8R; 17:49495441-49495441	kidney	other; neoplasm	Substitution - coding silent
c.377G>A; p.R126H; 17:49506467-49506467	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.895G>T; p.E299*; 17:49511965-49511965	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.626delC; p.S211fs*14; 17:49510469-49510469	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.933C>A; p.S311R; 17:49512003-49512003	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.196C>T; p.P66S; 17:49502192-49502192	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.185C>T; p.T62I; 17:49502181-49502181	skin	malignant_melanoma	Substitution - Missense
c.1120G>T; p.D374Y; 17:49512845-49512845	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.649G>T; p.A217S; 17:49510492-49510492	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.73C>T; p.L25F; 17:49502069-49502069	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.402C>T; p.L134L; 17:49506492-49506492	skin	malignant_melanoma	Substitution - coding silent
c.268G>A; p.V90M; 17:49506358-49506358	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.223G>A; p.D75N; 17:49506313-49506313	skin	malignant_melanoma	Substitution - Missense
c.288G>A; p.S96S; 17:49506378-49506378	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.453C>T; p.D151D; 17:49506543-49506543	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1147G>A; p.V383I; 17:49512872-49512872	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.67G>A; p.V23M; 17:49502063-49502063	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.802G>A; p.A268T; 17:49510645-49510645	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1132C>A; p.H378N; 17:49512857-49512857	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.459G>A; p.T153T; 17:49506549-49506549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.324C>A; p.R108R; 17:49506414-49506414	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1009A>G; p.S337G; 17:49512734-49512734	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.793G>T; p.G265C; 17:49510636-49510636	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.96C>A; p.C32*; 17:49502092-49502092	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.449C>A; p.P150H; 17:49506539-49506539	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.993T>C; p.G331G; 17:49512718-49512718	pancreas	carcinoma	Substitution - coding silent
c.219C>A; p.F73L; 17:49506309-49506309	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.962C>T; p.T321M; 17:49512032-49512032	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.262G>C; p.E88Q; 17:49506352-49506352	urinary_tract; bladder	carcinoma	Substitution - Missense
c.483G>A; p.V161V; 17:49506573-49506573	thyroid	carcinoma	Substitution - coding silent
c.520G>A; p.E174K; 17:49506610-49506610	skin	malignant_melanoma	Substitution - Missense
c.1124C>T; p.S375F; 17:49512849-49512849	skin	malignant_melanoma	Substitution - Missense
c.1124C>T; p.S375F; 17:49512849-49512849	skin	malignant_melanoma	Substitution - Missense
c.474C>A; p.A158A; 17:49506564-49506564	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.936G>C; p.Q312H; 17:49512006-49512006	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.215C>T; p.T72M; 17:49506305-49506305	pancreas	carcinoma	Substitution - Missense
c.120C>T; p.S40S; 17:49502116-49502116	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.640G>A; p.E214K; 17:49510483-49510483	skin	malignant_melanoma	Substitution - Missense
c.1198G>A; p.A400T; 17:49512923-49512923	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.652C>A; p.P218T; 17:49510495-49510495	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.372G>A; p.A124A; 17:49506462-49506462	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.267C>T; p.C89C; 17:49506357-49506357	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.720G>A; p.Q240Q; 17:49510563-49510563	skin	malignant_melanoma	Substitution - coding silent
c.552C>T; p.A184A; 17:49506642-49506642	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.267C>T; p.C89C; 17:49506357-49506357	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.294G>A; p.P98P; 17:49506384-49506384	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.821+1G>A; p.?; 17:49510665-49510665	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1063G>T; p.A355S; 17:49512788-49512788	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.477C>T; p.N159N; 17:49506567-49506567	skin	malignant_melanoma	Substitution - coding silent
c.974C>T; p.S325L; 17:49512044-49512044	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.453C>A; p.D151E; 17:49506543-49506543	thyroid	carcinoma; anaplastic_carcinoma	Substitution - Missense
c.1245G>C; p.E415D; 17:49512970-49512970	urinary_tract; bladder	carcinoma	Substitution - Missense
c.181C>A; p.Q61K; 17:49502177-49502177	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1039G>C; p.V347L; 17:49512764-49512764	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.838C>A; p.Q280K; 17:49511908-49511908	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.367G>A; p.E123K; 17:49506457-49506457	skin	malignant_melanoma	Substitution - Missense
c.1270A>T; p.T424S; 17:49512995-49512995	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.753C>T; p.L251L; 17:49510596-49510596	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1234G>A; p.D412N; 17:49512959-49512959	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1151G>A; p.R384H; 17:49512876-49512876	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.740C>A; p.T247N; 17:49510583-49510583	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.545G>A; p.R182H; 17:49506635-49506635	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1016T>C; p.L339P; 17:49512741-49512741	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1016T>C; p.L339P; 17:49512741-49512741	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.933C>T; p.S311S; 17:49512003-49512003	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.933C>T; p.S311S; 17:49512003-49512003	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.211G>A; p.V71M; 17:49506301-49506301	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1123T>C; p.S375P; 17:49512848-49512848	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.933C>T; p.S311S; 17:49512003-49512003	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.996C>T; p.D332D; 17:49512721-49512721	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1277C>T; p.P426L; 17:49513002-49513002	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.653C>A; p.P218H; 17:49510496-49510496	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.653C>A; p.P218H; 17:49510496-49510496	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.925G>A; p.V309M; 17:49511995-49511995	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.310G>A; p.D104N; 17:49506400-49506400	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.312C>T; p.D104D; 17:49506402-49506402	stomach	adenocarcinoma	Substitution - coding silent
c.411C>T; p.S137S; 17:49506501-49506501	skin	malignant_melanoma	Substitution - coding silent
c.918C>T; p.G306G; 17:49511988-49511988	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.175G>T; p.A59S; 17:49502171-49502171	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.254C>T; p.P85L; 17:49506344-49506344	skin	malignant_melanoma	Substitution - Missense
c.254C>T; p.P85L; 17:49506344-49506344	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.584G>T; p.W195L; 17:49510427-49510427	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]