Entrez Gene

Basic Information
Gene ID	4670
Name	HNRNPM
Synonymous	heterogeneous nuclear ribonucleoprotein M;HNRNPM;heterogeneous nuclear ribonucleoprotein M
Definition	CEA receptor\|N-acetylglucosamine receptor 1\|heterogenous nuclear ribonucleoprotein M4\|hnRNA-binding protein M4
Position	19p13.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1571G>A; p.R524H; 19:8485999-8485999	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1635_1636insG; p.P546fs*60; 19:8486063-8486064	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Insertion - Frameshift
c.1315C>T; p.L439L; 19:8485743-8485743	skin	malignant_melanoma	Substitution - coding silent
c.1744G>A; p.E582K; 19:8486172-8486172	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1839C>T; p.G613G; 19:8486267-8486267	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.730C>T; p.R244C; 19:8466334-8466334	breast	carcinoma	Substitution - Missense
c.700G>C; p.D234H; 19:8466304-8466304	breast	carcinoma	Substitution - Missense
c.1839C>T; p.G613G; 19:8486267-8486267	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1839C>T; p.G613G; 19:8486267-8486267	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1654G>A; p.A552T; 19:8486082-8486082	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.301G>A; p.V101M; 19:8462546-8462546	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1953G>T; p.K651N; 19:8486381-8486381	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.395T>C; p.L132P; 19:8463643-8463643	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1733G>A; p.R578H; 19:8486161-8486161	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1733G>A; p.R578H; 19:8486161-8486161	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1366C>T; p.R456C; 19:8485794-8485794	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.762C>T; p.S254S; 19:8466366-8466366	skin	malignant_melanoma	Substitution - coding silent
c.2028C>T; p.C676C; 19:8487074-8487074	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1025G>T; p.G342V; 19:8473691-8473691	skin	malignant_melanoma	Substitution - Missense
c.179G>A; p.R60H; 19:8455470-8455470	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.787A>G; p.M263V; 19:8467537-8467537	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.470T>C; p.M157T; 19:8465355-8465355	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.797G>A; p.G266D; 19:8467547-8467547	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1059T>C; p.F353F; 19:8474183-8474183	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1429G>C; p.E477Q; 19:8485857-8485857	parathyroid	adenoma	Substitution - Missense
c.2116G>A; p.E706K; 19:8488777-8488777	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1412G>C; p.R471P; 19:8485840-8485840	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1125C>G; p.I375M; 19:8483162-8483162	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.316G>A; p.D106N; 19:8462561-8462561	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1302C>T; p.I434I; 19:8485730-8485730	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1126C>T; p.L376L; 19:8483163-8483163	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1346G>A; p.R449H; 19:8485774-8485774	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1487G>A; p.R496H; 19:8485915-8485915	pancreas	carcinoma	Substitution - Missense
c.601A>G; p.R201G; 19:8465486-8465486	skin	malignant_melanoma	Substitution - Missense
c.2017T>A; p.F673I; 19:8487063-8487063	liver	carcinoma	Substitution - Missense
c.2017T>A; p.F673I; 19:8487063-8487063	liver	carcinoma	Substitution - Missense
c.1783G>A; p.A595T; 19:8486211-8486211	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1800G>T; p.L600L; 19:8486228-8486228	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1139T>C; p.L380P; 19:8483176-8483176	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.286G>T; p.G96C; 19:8462531-8462531	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1346G>T; p.R449L; 19:8485774-8485774	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.723A>C; p.G241G; 19:8466327-8466327	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.972C>T; p.I324I; 19:8471402-8471402	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.344C>T; p.A115V; 19:8463504-8463504	pancreas	carcinoma	Substitution - Missense
c.1096G>A; p.G366R; 19:8474220-8474220	skin	malignant_melanoma	Substitution - Missense
c.336+1G>C; p.?; 19:8462582-8462582	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1345C>T; p.R449C; 19:8485773-8485773	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1096G>A; p.G366R; 19:8474220-8474220	skin	malignant_melanoma	Substitution - Missense
c.1122A>C; p.E374D; 19:8483159-8483159	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.723A>G; p.G241G; 19:8466327-8466327	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1069A>T; p.M357L; 19:8474193-8474193	skin	malignant_melanoma	Substitution - Missense
c.2097C>T; p.F699F; 19:8488758-8488758	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1184G>A; p.G395E; 19:8485612-8485612	skin	malignant_melanoma	Substitution - Missense
c.1065T>C; p.G355G; 19:8474189-8474189	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1369A>G; p.M457V; 19:8485797-8485797	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.472C>G; p.Q158E; 19:8465357-8465357	ovary	other; neoplasm	Substitution - Missense
c.344+9C>G; p.?; 19:8463513-8463513	endometrium	carcinoma; serous_carcinoma	Unknown
c.792C>A; p.F264L; 19:8467542-8467542	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.381A>T; p.K127N; 19:8463629-8463629	liver	carcinoma	Substitution - Missense
c.631C>T; p.L211L; 19:8466235-8466235	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.381A>T; p.K127N; 19:8463629-8463629	liver	carcinoma	Substitution - Missense
c.381A>T; p.K127N; 19:8463629-8463629	liver	carcinoma	Substitution - Missense
c.630+7A>G; p.?; 19:8465522-8465522	liver	carcinoma	Unknown
c.630+7A>G; p.?; 19:8465522-8465522	liver	carcinoma	Unknown
c.408T>C; p.S136S; 19:8463656-8463656	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.141G>A; p.E47E; 19:8455432-8455432	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.688G>A; p.V230M; 19:8466292-8466292	skin	malignant_melanoma	Substitution - Missense
c.1546_1566del21; p.P520_G526delPAIERMG; 19:8485974-8485994	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; polycythaemia_vera	Deletion - In frame
c.928C>T; p.P310S; 19:8471358-8471358	skin	malignant_melanoma	Substitution - Missense
c.826G>A; p.V276I; 19:8467576-8467576	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2047G>A; p.D683N; 19:8488708-8488708	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1292G>A; p.G431D; 19:8485720-8485720	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.631-8T>C; p.?; 19:8466227-8466227	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.1266C>T; p.G422G; 19:8485694-8485694	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1414A>T; p.M472L; 19:8485842-8485842	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1454G>A; p.R485H; 19:8485882-8485882	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.48C>T; p.I16I; 19:8445046-8445046	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1453C>T; p.R485C; 19:8485881-8485881	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.374T>A; p.M125K; 19:8463622-8463622	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1296C>T; p.S432S; 19:8485724-8485724	ovary	other; neoplasm	Substitution - coding silent
c.1277G>A; p.G426D; 19:8485705-8485705	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1296C>T; p.S432S; 19:8485724-8485724	ovary	other; neoplasm	Substitution - coding silent
c.912T>A; p.I304I; 19:8471342-8471342	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1840G>A; p.G614S; 19:8486268-8486268	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2170G>A; p.V724I; 19:8488831-8488831	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.383C>G; p.A128G; 19:8463631-8463631	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1297G>A; p.E433K; 19:8485725-8485725	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1586T>C; p.M529T; 19:8486014-8486014	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.958C>A; p.L320M; 19:8471388-8471388	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.958C>T; p.L320L; 19:8471388-8471388	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1816C>T; p.R606C; 19:8486244-8486244	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.277G>T; p.E93*; 19:8455568-8455568	autonomic_ganglia	neuroblastoma	Substitution - Nonsense
c.838G>A; p.E280K; 19:8468777-8468777	breast	carcinoma	Substitution - Missense
c.1992C>T; p.F664F; 19:8487038-8487038	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.414C>T; p.S138S; 19:8463662-8463662	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2045C>T; p.A682V; 19:8488706-8488706	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1604C>T; p.A535V; 19:8486032-8486032	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1846G>A; p.G616S; 19:8486274-8486274	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.895+1G>A; p.?; 19:8468835-8468835	stomach	carcinoma; adenocarcinoma	Unknown
c.399C>A; p.N133K; 19:8463647-8463647	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2043C>T; p.Y681Y; 19:8488704-8488704	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1386C>A; p.L462L; 19:8485814-8485814	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.283G>T; p.V95F; 19:8455574-8455574	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1603G>A; p.A535T; 19:8486031-8486031	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1648C>T; p.R550C; 19:8486076-8486076	skin	malignant_melanoma	Substitution - Missense
c.912T>G; p.I304M; 19:8471342-8471342	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1447G>A; p.V483M; 19:8485875-8485875	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.608G>T; p.G203V; 19:8465493-8465493	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.641A>T; p.K214I; 19:8466245-8466245	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1387G>A; p.D463N; 19:8485815-8485815	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.835-9C>G; p.?; 19:8468765-8468765	ovary	other; neoplasm	Unknown
c.1752G>T; p.M584I; 19:8486180-8486180	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.334A>G; p.R112G; 19:8462579-8462579	skin	malignant_melanoma	Substitution - Missense
c.376_377insA; p.A128fs*9; 19:8463624-8463625	stomach	adenocarcinoma	Insertion - Frameshift
c.1234G>A; p.G412R; 19:8485662-8485662	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.583C>T; p.H195Y; 19:8465468-8465468	skin	malignant_melanoma	Substitution - Missense
c.1246A>G; p.M416V; 19:8485674-8485674	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1782T>C; p.P594P; 19:8486210-8486210	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1782T>C; p.P594P; 19:8486210-8486210	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1782T>C; p.P594P; 19:8486210-8486210	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1782T>C; p.P594P; 19:8486210-8486210	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1782T>C; p.P594P; 19:8486210-8486210	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1782T>C; p.P594P; 19:8486210-8486210	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1782T>C; p.P594P; 19:8486210-8486210	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1782T>C; p.P594P; 19:8486210-8486210	thyroid	other; neoplasm	Substitution - coding silent
c.1782T>C; p.P594P; 19:8486210-8486210	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1782T>C; p.P594P; 19:8486210-8486210	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1187G>A; p.G396E; 19:8485615-8485615	breast	carcinoma	Substitution - Missense
c.69C>A; p.G23G; 19:8445067-8445067	liver	carcinoma	Substitution - coding silent
c.1990T>A; p.F664I; 19:8487036-8487036	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.487A>G; p.T163A; 19:8465372-8465372	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.877C>T; p.R293C; 19:8468816-8468816	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1773_1784del12; p.M596_A599delMGPA; 19:8486201-8486212	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.864C>T; p.F288F; 19:8468803-8468803	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.415G>A; p.G139R; 19:8463663-8463663	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1228C>T; p.R410C; 19:8485656-8485656	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1326C>T; p.D442D; 19:8485754-8485754	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1738G>T; p.G580C; 19:8486166-8486166	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1297G>C; p.E433Q; 19:8485725-8485725	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2080T>G; p.C694G; 19:8488741-8488741	breast	carcinoma	Substitution - Missense
c.1418_1419GC>TT; p.G473V; 19:8485846-8485847	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1705_1728del24; p.A573_G580delANSLERMG; 19:8486133-8486156	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Deletion - In frame

COSMIC somatic mutation [Top]