Entrez Gene

Basic Information
Gene ID	4128
Name	MAOA
Synonymous	monoamine oxidase A;MAOA;monoamine oxidase A
Definition	amine oxidase [flavin-containing] A\|monoamine oxidase type A
Position	Xp11.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.656T>C; p.F219S; 23:43731251-43731251	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1078C>T; p.R360*; 23:43736252-43736252	skin	malignant_melanoma	Substitution - Nonsense
c.571G>T; p.A191S; 23:43728240-43728240	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.431G>T; p.W144L; 23:43712724-43712724	pancreas	carcinoma	Substitution - Missense
c.59G>A; p.G20E; 23:43656400-43656400	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.464T>C; p.M155T; 23:43712757-43712757	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.59G>A; p.G20E; 23:43656400-43656400	skin	malignant_melanoma	Substitution - Missense
c.982G>T; p.D328Y; 23:43732725-43732725	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.30G>A; p.A10A; 23:43656371-43656371	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.483T>C; p.I161I; 23:43712776-43712776	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.467C>A; p.T156N; 23:43712760-43712760	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1449G>A; p.A483A; 23:43744378-43744378	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1449G>A; p.A483A; 23:43744378-43744378	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1449G>A; p.A483A; 23:43744378-43744378	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.466A>T; p.T156S; 23:43712759-43712759	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1355G>A; p.G452E; 23:43743886-43743886	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.377A>G; p.N126S; 23:43711942-43711942	liver	carcinoma	Substitution - Missense
c.308G>A; p.G103E; 23:43711873-43711873	skin	malignant_melanoma	Substitution - Missense
c.1402G>A; p.E468K; 23:43744136-43744136	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1333A>G; p.M445V; 23:43743864-43743864	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1245C>G; p.I415M; 23:43742030-43742030	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.891G>T; p.R297R; 23:43731789-43731789	thyroid	other; neoplasm	Substitution - coding silent
c.891G>T; p.R297R; 23:43731789-43731789	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.340C>A; p.P114T; 23:43711905-43711905	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.347G>A; p.W116*; 23:43711912-43711912	skin	malignant_melanoma	Substitution - Nonsense
c.1270C>T; p.R424C; 23:43743801-43743801	skin	malignant_melanoma	Substitution - Missense
c.325C>T; p.R109W; 23:43711890-43711890	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.325C>T; p.R109W; 23:43711890-43711890	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1524C>T; p.S508S; 23:43744453-43744453	skin	malignant_melanoma	Substitution - coding silent
c.325C>T; p.R109W; 23:43711890-43711890	NS	NS	Substitution - Missense
c.74-2A>G; p.?; 23:43683511-43683511	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.1012G>A; p.D338N; 23:43732755-43732755	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.493T>G; p.C165G; 23:43712786-43712786	kidney	other; neoplasm	Substitution - Missense
c.565G>A; p.V189M; 23:43728234-43728234	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1150C>A; p.Q384K; 23:43740724-43740724	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1517G>C; p.G506A; 23:43744446-43744446	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.427C>T; p.P143S; 23:43712720-43712720	skin	malignant_melanoma	Substitution - Missense
c.1326C>T; p.S442S; 23:43743857-43743857	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1010T>C; p.L337S; 23:43732753-43732753	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.825G>A; p.P275P; 23:43731723-43731723	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1374+1G>T; p.?; 23:43743906-43743906	lung	carcinoma; non_small_cell_carcinoma	Unknown
c.1090C>A; p.L364I; 23:43736264-43736264	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.140G>A; p.R47K; 23:43683579-43683579	skin	malignant_melanoma	Substitution - Missense
c.399C>A; p.N133K; 23:43711964-43711964	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.357T>A; p.I119I; 23:43711922-43711922	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.890G>A; p.R297Q; 23:43731788-43731788	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.815C>T; p.A272V; 23:43731713-43731713	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.333C>T; p.A111A; 23:43711898-43711898	skin	malignant_melanoma	Substitution - coding silent
c.1194_1195insGAG; p.E400_Q401insE; 23:43741979-43741980	large_intestine; rectum	carcinoma; adenocarcinoma	Insertion - In frame
c.760A>G; p.I254V; 23:43731355-43731355	breast	carcinoma	Substitution - Missense
c.1435A>T; p.K479*; 23:43744169-43744169	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1268_1269insT; p.R424fs*27; 23:43743799-43743800	breast	carcinoma	Insertion - Frameshift
c.44A>G; p.D15G; 23:43656385-43656385	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.853C>T; p.P285S; 23:43731751-43731751	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.453A>C; p.K151N; 23:43712746-43712746	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.453A>G; p.K151K; 23:43712746-43712746	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1245C>T; p.I415I; 23:43742030-43742030	skin; head_neck	malignant_melanoma; superficial_spreading	Substitution - coding silent
c.562G>A; p.E188K; 23:43728231-43728231	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.872G>T; p.R291I; 23:43731770-43731770	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.148G>T; p.G50*; 23:43683587-43683587	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1001C>A; p.S334*; 23:43732744-43732744	central_nervous_system; brain	glioma; astrocytoma_Grade_III	Substitution - Nonsense
c.616C>T; p.R206W; 23:43728285-43728285	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1067G>A; p.R356Q; 23:43736241-43736241	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.980A>C; p.E327A; 23:43732723-43732723	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1556A>T; p.Y519F; 23:43744485-43744485	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.45C>A; p.D15E; 23:43656386-43656386	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.45C>A; p.D15E; 23:43656386-43656386	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.389C>T; p.T130I; 23:43711954-43711954	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1401C>T; p.T467T; 23:43744135-43744135	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1119C>T; p.I373I; 23:43740693-43740693	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1257T>C; p.Y419Y; 23:43742042-43742042	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.416C>T; p.P139L; 23:43712709-43712709	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1389C>T; p.L463L; 23:43744123-43744123	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1267_1268insT; p.R424fs*27; 23:43743798-43743799	breast	carcinoma	Insertion - Frameshift
c.466A>G; p.T156A; 23:43712759-43712759	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1423G>T; p.E475*; 23:43744157-43744157	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1559A>C; p.K520T; 23:43744488-43744488	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1278_1283delCGTGGG; p.V427_G428delVG; 23:43743809-43743814	ovary	carcinoma; serous_carcinoma	Deletion - In frame
c.239T>A; p.L80*; 23:43693361-43693361	soft_tissue; striated_muscle	rhabdomyosarcoma; alveolar	Substitution - Nonsense
c.561C>A; p.H187Q; 23:43728230-43728230	urinary_tract; bladder	carcinoma	Substitution - Missense
c.49G>C; p.V17L; 23:43656390-43656390	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1107-4A>T; p.?; 23:43740677-43740677	stomach	carcinoma; diffuse_adenocarcinoma	Unknown

COSMIC somatic mutation [Top]