Entrez Gene

Basic Information
Gene ID	4071
Name	TM4SF1
Synonymous	transmembrane 4 L six family member 1;TM4SF1;transmembrane 4 L six family member 1
Definition	membrane component chromosome 3 surface marker 1\|membrane component, chromosome 3, surface marker 1\|transmembrane 4 L6 family member 1\|transmembrane 4 superfamily member 1\|tumor-associated antigen L6
Position	3q21-q25
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.250T>G; p.C84G; 3:149375697-149375697	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.117C>T; p.S39S; 3:149377431-149377431	breast	carcinoma	Substitution - coding silent
c.317A>G; p.Y106C; 3:149375539-149375539	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.375C>T; p.L125L; 3:149375481-149375481	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.92C>T; p.P31L; 3:149377456-149377456	skin	malignant_melanoma	Substitution - Missense
c.86A>G; p.Y29C; 3:149377462-149377462	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.20C>T; p.A7V; 3:149377528-149377528	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.319T>A; p.C107S; 3:149375537-149375537	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.62G>C; p.C21S; 3:149377486-149377486	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.78T>G; p.I26M; 3:149377470-149377470	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.174G>A; p.L58L; 3:149377374-149377374	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.594+3A>G; p.?; 3:149371684-149371684	breast	carcinoma	Unknown
c.133C>T; p.R45C; 3:149377415-149377415	skin; leg	malignant_melanoma	Substitution - Missense
c.133C>T; p.R45C; 3:149377415-149377415	skin; leg	malignant_melanoma	Substitution - Missense
c.260G>T; p.R87L; 3:149375687-149375687	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.214C>A; p.Q72K; 3:149375733-149375733	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.17G>T; p.C6F; 3:149377531-149377531	breast	carcinoma	Substitution - Missense
c.409G>T; p.G137C; 3:149375447-149375447	ovary	other; neoplasm	Substitution - Missense
c.409G>T; p.G137C; 3:149375447-149375447	ovary	other; neoplasm	Substitution - Missense
c.308G>C; p.G103A; 3:149375548-149375548	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.118G>A; p.E40K; 3:149377430-149377430	skin	malignant_melanoma	Substitution - Missense
c.289G>T; p.A97S; 3:149375567-149375567	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.229G>T; p.G77C; 3:149375718-149375718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.74A>G; p.N25S; 3:149377474-149377474	pancreas	carcinoma	Substitution - Missense
c.116C>G; p.S39C; 3:149377432-149377432	breast	carcinoma	Substitution - Missense
c.535A>T; p.I179F; 3:149371746-149371746	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.491C>G; p.S164C; 3:149371790-149371790	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.26G>A; p.C9Y; 3:149377522-149377522	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.348A>G; p.A116A; 3:149375508-149375508	skin	malignant_melanoma	Substitution - coding silent
c.124C>A; p.H42N; 3:149377424-149377424	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]