Entrez Gene

Basic Information
Gene ID	3987
Name	LIMS1
Synonymous	LIM and senescent cell antigen-like domains 1;LIMS1;LIM and senescent cell antigen-like domains 1
Definition	LIM and senescent cell antigen-like-containing domain protein 1\|particularly interesting new Cys-His protein 1\|renal carcinoma antigen NY-REN-48
Position	2q12.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.941G>T; p.R314I; 2:108683962-108683962	breast	carcinoma	Substitution - Missense
c.31G>T; p.E11*; 2:108659639-108659639	breast	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.516A>T; p.A172A; 2:108675899-108675899	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.516A>T; p.A172A; 2:108675899-108675899	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.609C>T; p.R203R; 2:108675992-108675992	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.609C>T; p.R203R; 2:108675992-108675992	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.607C>G; p.R203G; 2:108675990-108675990	urinary_tract; bladder	carcinoma	Substitution - Missense
c.816C>T; p.C272C; 2:108680723-108680723	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.158T>C; p.F53S; 2:108670782-108670782	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.53C>T; p.A18V; 2:108659661-108659661	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.53C>T; p.A18V; 2:108659661-108659661	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.58G>A; p.A20T; 2:108659666-108659666	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.275C>T; p.P92L; 2:108672376-108672376	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.108C>T; p.F36F; 2:108659716-108659716	breast	carcinoma	Substitution - coding silent
c.108C>T; p.F36F; 2:108659716-108659716	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.7A>G; p.N3D; 2:108659615-108659615	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.97G>C; p.E33Q; 2:108659705-108659705	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.432G>T; p.E144D; 2:108672967-108672967	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.714A>G; p.A238A; 2:108676674-108676674	breast	carcinoma	Substitution - coding silent
c.714A>G; p.A238A; 2:108676674-108676674	breast	carcinoma	Substitution - coding silent
c.114C>T; p.C38C; 2:108659722-108659722	thyroid	other; neoplasm	Substitution - coding silent
c.114C>T; p.C38C; 2:108659722-108659722	thyroid	other; neoplasm	Substitution - coding silent
c.126C>T; p.F42F; 2:108659734-108659734	skin	malignant_melanoma	Substitution - coding silent
c.688C>T; p.R230C; 2:108676648-108676648	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.142G>T; p.G48*; 2:108659750-108659750	skin	malignant_melanoma	Substitution - Nonsense
c.512A>G; p.D171G; 2:108675895-108675895	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.560A>C; p.K187T; 2:108675943-108675943	ovary	other; neoplasm	Substitution - Missense
c.885C>G; p.D295E; 2:108683906-108683906	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.929A>C; p.E310A; 2:108683950-108683950	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.787+1_787+4delGTAA; p.?; 2:108678028-108678031	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.689G>A; p.R230H; 2:108676649-108676649	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.150C>T; p.F50F; 2:108659758-108659758	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.685C>T; p.H229Y; 2:108676645-108676645	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.35G>A; p.R12H; 2:108659643-108659643	thyroid	other; neoplasm	Substitution - Missense
c.35G>A; p.R12H; 2:108659643-108659643	thyroid	other; neoplasm	Substitution - Missense
c.35G>A; p.R12H; 2:108659643-108659643	thyroid	other; neoplasm	Substitution - Missense
c.32A>G; p.E11G; 2:108659640-108659640	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]