| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3957 |
Name | LGALS2 |
Synonymous | lectin, galactoside-binding, soluble, 2;LGALS2;lectin, galactoside-binding, soluble, 2 |
Definition | S-Lac lectin 2|beta-galactoside-binding lectin L-14-II|gal-2|galectin 2|galectin-2|lactose-binding lectin 2 |
Position | 22q13.1 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.133C>T; p.H45Y; 22:37570692-37570692 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.206_208delAAC; p.Q69delQ; 22:37570617-37570619 |
oesophagus | carcinoma; adenocarcinoma | Deletion - In frame |
c.90-2A>G; p.?; 22:37570737-37570737 |
central_nervous_system; brain | glioma | Unknown |
c.139A>T; p.N47Y; 22:37570686-37570686 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.355G>A; p.V119I; 22:37570307-37570307 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.355G>A; p.V119I; 22:37570307-37570307 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.250-6C>G; p.?; 22:37570418-37570418 |
biliary_tract; gallbladder | carcinoma; adenocarcinoma | Unknown |
c.232C>A; p.P78T; 22:37570593-37570593 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.397T>A; p.*133K; 22:37570265-37570265 |
skin; upper_arm | malignant_melanoma | Nonstop extension |
c.179T>C; p.L60S; 22:37570646-37570646 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.352A>T; p.S118C; 22:37570310-37570310 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.362G>A; p.G121D; 22:37570300-37570300 |
kidney | carcinoma; papillary_renal_cell_carcinoma | Substitution - Missense |
c.9G>A; p.G3G; 22:37571929-37571929 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - coding silent |
c.377C>T; p.S126F; 22:37570285-37570285 |
skin | malignant_melanoma | Substitution - Missense |
c.205C>G; p.Q69E; 22:37570620-37570620 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.199C>T; p.Q67*; 22:37570626-37570626 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Nonsense |
c.236G>A; p.G79E; 22:37570589-37570589 |
skin | malignant_melanoma | Substitution - Missense |
c.304G>T; p.E102*; 22:37570358-37570358 |
breast | carcinoma | Substitution - Nonsense |
c.304G>T; p.E102*; 22:37570358-37570358 |
lung; right_lower_lobe | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.90-9C>A; p.?; 22:37570744-37570744 |
large_intestine; rectum | carcinoma; adenocarcinoma | Unknown |
c.249G>A; p.K83K; 22:37570576-37570576 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.394G>C; p.E132Q; 22:37570268-37570268 |
breast | carcinoma; ductal_carcinoma | Substitution - Missense |
c.216T>C; p.D72D; 22:37570609-37570609 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.241G>A; p.E81K; 22:37570584-37570584 |
lung; right_lower_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.220C>A; p.L74M; 22:37570605-37570605 |
pancreas | carcinoma | Substitution - Missense |
c.184_185GG>AA; p.G62N; 22:37570640-37570641 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.233C>A; p.P78Q; 22:37570592-37570592 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.351G>A; p.L117L; 22:37570311-37570311 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.148T>A; p.F50I; 22:37570677-37570677 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |