Entrez Gene

Basic Information
Gene ID	3912
Name	LAMB1
Synonymous	laminin, beta 1;LAMB1;laminin, beta 1
Definition	laminin B1 chain\|laminin subunit beta-1
Position	7q22
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.602C>A; p.T201N; 7:107986185-107986185	urinary_tract; bladder	carcinoma	Substitution - Missense
c.255T>A; p.Y85*; 7:107998451-107998451	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.4280G>A; p.G1427E; 7:107932286-107932286	breast	carcinoma	Substitution - Missense
c.4649G>T; p.R1550L; 7:107929508-107929508	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1290A>C; p.L430F; 7:107975313-107975313	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.783A>G; p.A261A; 7:107980705-107980705	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.447G>T; p.L149L; 7:107986340-107986340	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2629G>A; p.D877N; 7:107959310-107959310	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2629G>A; p.D877N; 7:107959310-107959310	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.4939C>T; p.R1647C; 7:107926308-107926308	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4939C>T; p.R1647C; 7:107926308-107926308	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1870T>A; p.W624R; 7:107961664-107961664	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4009G>T; p.A1337S; 7:107935594-107935594	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4240C>T; p.P1414S; 7:107932326-107932326	liver	carcinoma	Substitution - Missense
c.3964A>G; p.T1322A; 7:107935639-107935639	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4929C>T; p.N1643N; 7:107926318-107926318	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4240C>T; p.P1414S; 7:107932326-107932326	liver	carcinoma	Substitution - Missense
c.1678G>A; p.E560K; 7:107964572-107964572	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.4835C>T; p.A1612V; 7:107929116-107929116	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.3450G>T; p.Q1150H; 7:107940300-107940300	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.4131C>G; p.L1377L; 7:107935472-107935472	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4904C>G; p.A1635G; 7:107926343-107926343	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1776T>G; p.P592P; 7:107962986-107962986	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1776T>G; p.P592P; 7:107962986-107962986	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2569G>C; p.G857R; 7:107959370-107959370	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1371T>C; p.S457S; 7:107975097-107975097	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.842C>T; p.A281V; 7:107980646-107980646	liver	carcinoma	Substitution - Missense
c.3033C>T; p.F1011F; 7:107953576-107953576	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.3408C>A; p.P1136P; 7:107940342-107940342	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.4789G>T; p.E1597*; 7:107929162-107929162	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Nonsense
c.3295T>C; p.F1099L; 7:107951322-107951322	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.498C>T; p.F166F; 7:107986289-107986289	skin	malignant_melanoma	Substitution - coding silent
c.498C>T; p.F166F; 7:107986289-107986289	skin	malignant_melanoma	Substitution - coding silent
c.4258G>A; p.E1420K; 7:107932308-107932308	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4080G>C; p.M1360I; 7:107935523-107935523	liver	carcinoma	Substitution - Missense
c.3704C>T; p.A1235V; 7:107940046-107940046	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; peripheral_T_cell_lymphoma_unspecified	Substitution - Missense
c.4258G>A; p.E1420K; 7:107932308-107932308	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3276C>T; p.F1092F; 7:107952027-107952027	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.4080G>C; p.M1360I; 7:107935523-107935523	liver	carcinoma	Substitution - Missense
c.2212C>G; p.R738G; 7:107960547-107960547	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.2891G>A; p.G964D; 7:107953718-107953718	thyroid	carcinoma	Substitution - Missense
c.4310C>T; p.A1437V; 7:107932256-107932256	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1656G>A; p.L552L; 7:107964594-107964594	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.546G>T; p.M182I; 7:107986241-107986241	skin; ear	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5228T>C; p.L1743S; 7:107924084-107924084	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3510G>T; p.S1170S; 7:107940240-107940240	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.4424C>G; p.A1475G; 7:107931469-107931469	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.5301A>C; p.E1767D; 7:107924011-107924011	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.152C>T; p.S51L; 7:108001619-108001619	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3860C>T; p.S1287F; 7:107937179-107937179	breast	carcinoma	Substitution - Missense
c.2387C>T; p.P796L; 7:107959762-107959762	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2325C>T; p.C775C; 7:107959824-107959824	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.978C>T; p.G326G; 7:107978069-107978069	skin	malignant_melanoma	Substitution - coding silent
c.2350G>A; p.V784M; 7:107959799-107959799	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3844G>A; p.A1282T; 7:107937195-107937195	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1214C>T; p.S405F; 7:107975389-107975389	skin	malignant_melanoma	Substitution - Missense
c.1559A>G; p.N520S; 7:107972995-107972995	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4568C>T; p.A1523V; 7:107929589-107929589	lung; left_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4851T>A; p.D1617E; 7:107929100-107929100	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1031G>C; p.C344S; 7:107975847-107975847	ovary	other; neoplasm	Substitution - Missense
c.5305C>T; p.R1769C; 7:107924007-107924007	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4173A>G; p.S1391S; 7:107935430-107935430	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.4177G>A; p.A1393T; 7:107935426-107935426	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4236C>T; p.G1412G; 7:107932330-107932330	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2060A>T; p.Y687F; 7:107961255-107961255	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.865G>T; p.E289*; 7:107980623-107980623	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.813C>A; p.C271*; 7:107980675-107980675	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1369+7C>T; p.?; 7:107975227-107975227	pancreas	carcinoma	Unknown
c.1126C>T; p.Q376*; 7:107975752-107975752	liver	carcinoma	Substitution - Nonsense
c.1126C>T; p.Q376*; 7:107975752-107975752	liver	carcinoma	Substitution - Nonsense
c.1126C>T; p.Q376*; 7:107975752-107975752	liver	carcinoma; hepatocellular_carcinoma	Substitution - Nonsense
c.5126_5127insA; p.E1710fs*1; 7:107924327-107924328	skin; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.2915C>A; p.S972*; 7:107953694-107953694	breast	carcinoma	Substitution - Nonsense
c.60C>T; p.R20R; 7:108001711-108001711	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.5125delA; p.T1709fs*22; 7:107924329-107924329	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.276C>T; p.D92D; 7:107998430-107998430	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1038T>C; p.F346F; 7:107975840-107975840	skin	malignant_melanoma	Substitution - coding silent
c.595C>G; p.P199A; 7:107986192-107986192	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.592G>A; p.E198K; 7:107986195-107986195	breast	carcinoma	Substitution - Missense
c.3199C>T; p.R1067C; 7:107952104-107952104	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4569A>C; p.A1523A; 7:107929588-107929588	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2386C>G; p.P796A; 7:107959763-107959763	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1334A>G; p.Y445C; 7:107975269-107975269	oesophagus	carcinoma	Substitution - Missense
c.4746-1G>C; p.?; 7:107929206-107929206	breast	carcinoma; basal_(triple-negative)_carcinoma	Unknown
c.3482G>A; p.R1161H; 7:107940268-107940268	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.3482G>A; p.R1161H; 7:107940268-107940268	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4084G>A; p.E1362K; 7:107935519-107935519	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.5288G>C; p.R1763T; 7:107924024-107924024	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.5288G>C; p.R1763T; 7:107924024-107924024	breast	carcinoma	Substitution - Missense
c.1732G>T; p.D578Y; 7:107963030-107963030	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3253A>G; p.N1085D; 7:107952050-107952050	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.499G>A; p.A167T; 7:107986288-107986288	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3355G>T; p.E1119*; 7:107951262-107951262	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3946+2T>C; p.?; 7:107937091-107937091	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.454C>T; p.R152*; 7:107986333-107986333	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Nonsense
c.2712C>T; p.G904G; 7:107955609-107955609	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2712C>T; p.G904G; 7:107955609-107955609	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1567T>G; p.F523V; 7:107964683-107964683	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2712C>T; p.G904G; 7:107955609-107955609	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3420G>A; p.E1140E; 7:107940330-107940330	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3999G>A; p.E1333E; 7:107935604-107935604	skin	malignant_melanoma	Substitution - coding silent
c.2922G>A; p.Q974Q; 7:107953687-107953687	breast	carcinoma	Substitution - coding silent
c.2669C>T; p.T890I; 7:107959270-107959270	skin	malignant_melanoma	Substitution - Missense
c.1760G>A; p.G587D; 7:107963002-107963002	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3559G>A; p.D1187N; 7:107940191-107940191	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.4087C>T; p.R1363*; 7:107935516-107935516	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.3413G>A; p.G1138D; 7:107940337-107940337	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.316A>G; p.N106D; 7:107998390-107998390	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1369+1G>T; p.?; 7:107975233-107975233	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Unknown
c.1785T>G; p.A595A; 7:107962977-107962977	large_intestine; colon	adenoma	Substitution - coding silent
c.4746-3C>G; p.?; 7:107929208-107929208	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1114C>T; p.R372C; 7:107975764-107975764	prostate	carcinoma	Substitution - Missense
c.2349C>T; p.S783S; 7:107959800-107959800	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.470G>A; p.G157E; 7:107986317-107986317	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.2349C>T; p.S783S; 7:107959800-107959800	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.2349C>T; p.S783S; 7:107959800-107959800	skin	malignant_melanoma	Substitution - coding silent
c.4201C>T; p.P1401S; 7:107932365-107932365	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.518C>T; p.S173L; 7:107986269-107986269	skin	malignant_melanoma	Substitution - Missense
c.518C>T; p.S173L; 7:107986269-107986269	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.518C>T; p.S173L; 7:107986269-107986269	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2091C>T; p.P697P; 7:107961224-107961224	skin	malignant_melanoma	Substitution - coding silent
c.538_539GG>TC; p.G180>?; 7:107986248-107986249	lung	carcinoma; adenocarcinoma	Complex
c.2617G>C; p.A873P; 7:107959322-107959322	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1061C>T; p.T354M; 7:107975817-107975817	oesophagus	carcinoma	Substitution - Missense
c.2505C>T; p.P835P; 7:107959434-107959434	central_nervous_system; medulla	primitive_neuroectodermal_tumour-medulloblastoma; classic	Substitution - coding silent
c.3538C>A; p.H1180N; 7:107940212-107940212	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3496A>G; p.T1166A; 7:107940254-107940254	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.2007G>A; p.P669P; 7:107961308-107961308	ovary	other; neoplasm	Substitution - coding silent
c.1678G>C; p.E560Q; 7:107964572-107964572	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2203C>A; p.Q735K; 7:107960556-107960556	breast	carcinoma	Substitution - Missense
c.979C>T; p.R327*; 7:107978068-107978068	breast	carcinoma	Substitution - Nonsense
c.806G>A; p.G269E; 7:107980682-107980682	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1602C>A; p.H534Q; 7:107964648-107964648	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4371A>T; p.E1457D; 7:107932195-107932195	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; peripheral_T_cell_lymphoma_unspecified	Substitution - Missense
c.1849G>A; p.E617K; 7:107962913-107962913	parathyroid	adenoma	Substitution - Missense
c.5182delA; p.T1728fs*3; 7:107924272-107924272	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2700T>C; p.A900A; 7:107955621-107955621	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.3097C>A; p.L1033M; 7:107952206-107952206	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.424-1G>A; p.?; 7:107986364-107986364	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1634C>G; p.P545R; 7:107964616-107964616	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.3389G>A; p.R1130Q; 7:107951228-107951228	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3389G>A; p.R1130Q; 7:107951228-107951228	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3389G>A; p.R1130Q; 7:107951228-107951228	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2887T>G; p.F963V; 7:107953722-107953722	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2652G>A; p.L884L; 7:107959287-107959287	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.133G>T; p.G45C; 7:108001638-108001638	pancreas	carcinoma	Substitution - Missense
c.968C>A; p.P323H; 7:107978079-107978079	liver	carcinoma	Substitution - Missense
c.1447C>T; p.R483C; 7:107975021-107975021	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3154G>T; p.G1052C; 7:107952149-107952149	central_nervous_system; thalamus	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.4798G>A; p.E1600K; 7:107929153-107929153	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.320G>A; p.R107H; 7:107998386-107998386	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1843C>T; p.R615C; 7:107962919-107962919	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1315G>T; p.V439F; 7:107975288-107975288	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1843C>T; p.R615C; 7:107962919-107962919	skin	malignant_melanoma	Substitution - Missense
c.3344G>A; p.S1115N; 7:107951273-107951273	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1333T>C; p.Y445H; 7:107975270-107975270	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1280G>A; p.R427Q; 7:107975323-107975323	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.599C>A; p.S200*; 7:107986188-107986188	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Nonsense
c.347A>C; p.N116T; 7:107998359-107998359	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.599C>A; p.S200*; 7:107986188-107986188	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.2458+1G>A; p.?; 7:107959690-107959690	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.5006C>A; p.A1669E; 7:107926241-107926241	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; peripheral_T_cell_lymphoma_unspecified	Substitution - Missense
c.1675G>T; p.A559S; 7:107964575-107964575	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1429G>A; p.G477S; 7:107975039-107975039	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4998C>A; p.S1666S; 7:107926249-107926249	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4999G>T; p.G1667W; 7:107926248-107926248	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1836C>T; p.I612I; 7:107962926-107962926	skin	malignant_melanoma	Substitution - coding silent
c.4729G>T; p.E1577*; 7:107929428-107929428	breast	carcinoma	Substitution - Nonsense
c.1459G>A; p.G487R; 7:107975009-107975009	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4623G>T; p.Q1541H; 7:107929534-107929534	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4959G>A; p.R1653R; 7:107926288-107926288	thyroid	other; neoplasm	Substitution - coding silent
c.5234G>C; p.R1745T; 7:107924078-107924078	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1780G>T; p.G594W; 7:107962982-107962982	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4001G>T; p.R1334M; 7:107935602-107935602	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.3639C>A; p.I1213I; 7:107940111-107940111	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.4912G>A; p.E1638K; 7:107926335-107926335	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4135G>C; p.D1379H; 7:107935468-107935468	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2585C>T; p.P862L; 7:107959354-107959354	skin	malignant_melanoma	Substitution - Missense
c.231C>A; p.F77L; 7:107998475-107998475	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1181T>C; p.F394S; 7:107975697-107975697	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.231C>A; p.F77L; 7:107998475-107998475	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1897C>T; p.R633*; 7:107961637-107961637	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.5202T>C; p.N1734N; 7:107924252-107924252	liver	carcinoma	Substitution - coding silent
c.4958G>A; p.R1653K; 7:107926289-107926289	thyroid	other; neoplasm	Substitution - Missense
c.4017C>T; p.T1339T; 7:107935586-107935586	breast	carcinoma	Substitution - coding silent
c.3266C>G; p.A1089G; 7:107952037-107952037	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3460G>A; p.V1154I; 7:107940290-107940290	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2713G>A; p.D905N; 7:107955608-107955608	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5306G>A; p.R1769H; 7:107924006-107924006	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.5306G>A; p.R1769H; 7:107924006-107924006	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3207G>A; p.A1069A; 7:107952096-107952096	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.5186T>A; p.L1729H; 7:107924268-107924268	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2886C>T; p.Y962Y; 7:107953723-107953723	skin	malignant_melanoma	Substitution - coding silent
c.3381G>T; p.V1127V; 7:107951236-107951236	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2551T>C; p.C851R; 7:107959388-107959388	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2364C>A; p.N788K; 7:107959785-107959785	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.310G>A; p.A104T; 7:107998396-107998396	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.1171G>T; p.D391Y; 7:107975707-107975707	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.927_928delTG; p.C309fs*1; 7:107978119-107978120	endometrium	carcinoma; endometrioid_carcinoma	Deletion - Frameshift
c.2074A>G; p.S692G; 7:107961241-107961241	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3317T>C; p.M1106T; 7:107951300-107951300	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2612G>T; p.G871V; 7:107959327-107959327	central_nervous_system; brain	glioma; oligodendroglioma_Grade_III	Substitution - Missense
c.1297G>A; p.E433K; 7:107975306-107975306	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1830C>T; p.Y610Y; 7:107962932-107962932	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3572C>T; p.A1191V; 7:107940178-107940178	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1118A>C; p.N373T; 7:107975760-107975760	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2150C>T; p.T717I; 7:107960609-107960609	skin	malignant_melanoma	Substitution - Missense
c.4562T>C; p.I1521T; 7:107929595-107929595	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.4562T>C; p.I1521T; 7:107929595-107929595	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4562T>C; p.I1521T; 7:107929595-107929595	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5084A>G; p.D1695G; 7:107924370-107924370	liver	carcinoma	Substitution - Missense
c.5084A>G; p.D1695G; 7:107924370-107924370	liver	carcinoma	Substitution - Missense
c.1273C>G; p.Q425E; 7:107975330-107975330	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3629G>A; p.S1210N; 7:107940121-107940121	skin	malignant_melanoma	Substitution - Missense
c.612G>C; p.E204D; 7:107986175-107986175	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1081G>A; p.V361M; 7:107975797-107975797	central_nervous_system; brain	glioma	Substitution - Missense
c.1407G>A; p.G469G; 7:107975061-107975061	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4111C>T; p.Q1371*; 7:107935492-107935492	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.5008G>C; p.E1670Q; 7:107926239-107926239	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2725G>C; p.G909R; 7:107955596-107955596	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2513G>T; p.G838V; 7:107959426-107959426	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4877T>G; p.L1626R; 7:107929074-107929074	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1863C>T; p.P621P; 7:107961671-107961671	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1694G>A; p.G565E; 7:107964556-107964556	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1986-3C>A; p.?; 7:107961332-107961332	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Unknown
c.2089C>T; p.P697S; 7:107961226-107961226	skin; head_neck	malignant_melanoma; superficial_spreading	Substitution - Missense
c.3111A>T; p.Q1037H; 7:107952192-107952192	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.684A>C; p.L228F; 7:107980804-107980804	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2617G>T; p.A873S; 7:107959322-107959322	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.815T>C; p.F272S; 7:107980673-107980673	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1582C>T; p.Q528*; 7:107964668-107964668	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.4781T>C; p.M1594T; 7:107929170-107929170	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4074C>T; p.D1358D; 7:107935529-107935529	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4091A>T; p.E1364V; 7:107935512-107935512	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4342G>T; p.D1448Y; 7:107932224-107932224	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1183T>C; p.C395R; 7:107975695-107975695	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3468T>C; p.G1156G; 7:107940282-107940282	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1768C>T; p.R590*; 7:107962994-107962994	pancreas	carcinoma	Substitution - Nonsense
c.1768C>T; p.R590*; 7:107962994-107962994	pancreas	carcinoma	Substitution - Nonsense
c.1931G>C; p.G644A; 7:107961603-107961603	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.196A>T; p.I66F; 7:108001575-108001575	skin	malignant_melanoma	Substitution - Missense
c.594A>T; p.E198D; 7:107986193-107986193	pancreas	carcinoma	Substitution - Missense
c.3963T>A; p.I1321I; 7:107935640-107935640	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.462C>T; p.S154S; 7:107986325-107986325	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4082T>C; p.M1361T; 7:107935521-107935521	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4180G>A; p.A1394T; 7:107935423-107935423	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.526G>A; p.G176S; 7:107986261-107986261	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4448T>G; p.L1483R; 7:107931445-107931445	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1547_1548insG; p.A517fs*42; 7:107973006-107973007	liver	carcinoma; hepatocellular_carcinoma	Insertion - Frameshift
c.840T>C; p.C280C; 7:107980648-107980648	pancreas	carcinoma	Substitution - coding silent
c.2793G>A; p.R931R; 7:107955528-107955528	skin	malignant_melanoma	Substitution - coding silent
c.514G>A; p.A172T; 7:107986273-107986273	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4861C>A; p.Q1621K; 7:107929090-107929090	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1764C>T; p.F588F; 7:107962998-107962998	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2069C>T; p.S690F; 7:107961246-107961246	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2198C>T; p.T733I; 7:107960561-107960561	skin	malignant_melanoma	Substitution - Missense
c.33C>G; p.F11L; 7:108002853-108002853	NS	NS	Substitution - Missense
c.900C>T; p.C300C; 7:107978147-107978147	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.458C>T; p.S153L; 7:107986329-107986329	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.730G>T; p.G244*; 7:107980758-107980758	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.458C>T; p.S153L; 7:107986329-107986329	skin	malignant_melanoma	Substitution - Missense
c.4886C>T; p.S1629L; 7:107929065-107929065	prostate	carcinoma	Substitution - Missense
c.2076C>T; p.S692S; 7:107961239-107961239	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.350-1G>T; p.?; 7:107994961-107994961	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.3503G>C; p.G1168A; 7:107940247-107940247	breast	carcinoma	Substitution - Missense
c.1652C>T; p.T551I; 7:107964598-107964598	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1479C>T; p.C493C; 7:107974989-107974989	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4999G>C; p.G1667R; 7:107926248-107926248	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2292C>T; p.A764A; 7:107960467-107960467	skin	malignant_melanoma	Substitution - coding silent
c.584C>T; p.S195F; 7:107986203-107986203	NS	malignant_melanoma	Substitution - Missense
c.2462G>T; p.C821F; 7:107959477-107959477	liver	carcinoma	Substitution - Missense
c.1583A>G; p.Q528R; 7:107964667-107964667	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.669G>T; p.R223S; 7:107986029-107986029	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3482G>C; p.R1161P; 7:107940268-107940268	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2458C>T; p.P820S; 7:107959691-107959691	prostate	carcinoma	Substitution - Missense
c.2458C>T; p.P820S; 7:107959691-107959691	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3398A>G; p.D1133G; 7:107940352-107940352	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2375G>T; p.C792F; 7:107959774-107959774	thyroid	other; neoplasm	Substitution - Missense
c.750C>T; p.S250S; 7:107980738-107980738	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3277G>A; p.G1093R; 7:107952026-107952026	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4257C>G; p.D1419E; 7:107932309-107932309	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.81C>A; p.S27R; 7:108001690-108001690	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.214G>A; p.E72K; 7:107998492-107998492	breast	carcinoma	Substitution - Missense
c.1058C>T; p.A353V; 7:107975820-107975820	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4978C>T; p.R1660W; 7:107926269-107926269	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.578G>C; p.R193P; 7:107986209-107986209	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1580G>A; p.G527D; 7:107964670-107964670	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3080A>C; p.K1027T; 7:107952223-107952223	large_intestine; colon	carcinoma	Substitution - Missense
c.4790A>T; p.E1597V; 7:107929161-107929161	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1595G>A; p.R532Q; 7:107964655-107964655	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3684C>T; p.S1228S; 7:107940066-107940066	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3684C>T; p.S1228S; 7:107940066-107940066	skin	malignant_melanoma	Substitution - coding silent
c.4759G>C; p.D1587H; 7:107929192-107929192	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2314+2T>G; p.?; 7:107960443-107960443	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.5157C>T; p.A1719A; 7:107924297-107924297	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2553T>C; p.C851C; 7:107959386-107959386	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.459G>A; p.S153S; 7:107986328-107986328	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.72C>A; p.P24P; 7:108001699-108001699	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1948G>T; p.D650Y; 7:107961586-107961586	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.622C>T; p.R208C; 7:107986076-107986076	skin	malignant_melanoma	Substitution - Missense
c.622C>T; p.R208C; 7:107986076-107986076	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2643G>T; p.G881G; 7:107959296-107959296	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4528T>G; p.F1510V; 7:107931365-107931365	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2364C>T; p.N788N; 7:107959785-107959785	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.4201C>A; p.P1401T; 7:107932365-107932365	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5225-10C>A; p.?; 7:107924097-107924097	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.3944G>A; p.R1315Q; 7:107937095-107937095	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4318G>A; p.A1440T; 7:107932248-107932248	prostate	carcinoma	Substitution - Missense
c.4318G>A; p.A1440T; 7:107932248-107932248	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1549G>A; p.A517T; 7:107973005-107973005	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4318G>A; p.A1440T; 7:107932248-107932248	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2976G>T; p.K992N; 7:107953633-107953633	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1925G>A; p.R642Q; 7:107961609-107961609	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.169G>A; p.G57R; 7:108001602-108001602	liver	carcinoma	Substitution - Missense
c.3523G>C; p.D1175H; 7:107940227-107940227	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.3497C>T; p.T1166M; 7:107940253-107940253	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.169G>A; p.G57R; 7:108001602-108001602	liver	carcinoma	Substitution - Missense
c.1168C>T; p.R390*; 7:107975710-107975710	liver	carcinoma	Substitution - Nonsense
c.2716C>A; p.P906T; 7:107955605-107955605	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1168C>T; p.R390*; 7:107975710-107975710	liver	carcinoma	Substitution - Nonsense
c.2489A>G; p.N830S; 7:107959450-107959450	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1168C>T; p.R390*; 7:107975710-107975710	liver	carcinoma	Substitution - Nonsense
c.1168C>T; p.R390*; 7:107975710-107975710	liver	carcinoma	Substitution - Nonsense
c.1044G>C; p.M348I; 7:107975834-107975834	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3077G>A; p.R1026Q; 7:107953532-107953532	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3077G>A; p.R1026Q; 7:107953532-107953532	breast	carcinoma	Substitution - Missense
c.3077G>A; p.R1026Q; 7:107953532-107953532	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3397G>A; p.D1133N; 7:107940353-107940353	NS	NS	Substitution - Missense
c.2008G>T; p.V670L; 7:107961307-107961307	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2339C>T; p.S780L; 7:107959810-107959810	skin	malignant_melanoma	Substitution - Missense
c.2339C>T; p.S780L; 7:107959810-107959810	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2339C>T; p.S780L; 7:107959810-107959810	skin	malignant_melanoma	Substitution - Missense
c.2008G>T; p.V670L; 7:107961307-107961307	ovary	other; neoplasm	Substitution - Missense
c.1051T>C; p.Y351H; 7:107975827-107975827	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4423G>A; p.A1475T; 7:107931470-107931470	skin; arm	malignant_melanoma	Substitution - Missense
c.1279C>T; p.R427W; 7:107975324-107975324	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3109C>A; p.Q1037K; 7:107952194-107952194	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4279G>T; p.G1427W; 7:107932287-107932287	liver	carcinoma	Substitution - Missense
c.5336T>G; p.V1779G; 7:107923976-107923976	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4088G>A; p.R1363Q; 7:107935515-107935515	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3378C>T; p.D1126D; 7:107951239-107951239	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.2211C>T; p.Y737Y; 7:107960548-107960548	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.832A>T; p.S278C; 7:107980656-107980656	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.930A>G; p.E310E; 7:107978117-107978117	liver	carcinoma	Substitution - coding silent
c.930A>G; p.E310E; 7:107978117-107978117	liver	carcinoma	Substitution - coding silent
c.2770G>T; p.D924Y; 7:107955551-107955551	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3578T>C; p.L1193P; 7:107940172-107940172	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.2743C>A; p.R915S; 7:107955578-107955578	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3394T>C; p.C1132R; 7:107940356-107940356	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.3994G>A; p.E1332K; 7:107935609-107935609	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5297G>A; p.G1766E; 7:107924015-107924015	skin	malignant_melanoma	Substitution - Missense

COSMIC somatic mutation [Top]