Entrez Gene

Basic Information
Gene ID	3627
Name	CXCL10
Synonymous	chemokine (C-X-C motif) ligand 10;CXCL10;chemokine (C-X-C motif) ligand 10
Definition	10 kDa interferon gamma-induced protein\|C-X-C motif chemokine 10\|gamma IP10\|gamma-IP10\|interferon-inducible cytokine IP-10\|protein 10 from interferon (gamma)-induced cell line\|small inducible cytokine subfamily B (Cys-X-Cys), member 10\|small-inducible cyt
Position	4q21
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.249G>T; p.K83N; 4:76022395-76022395	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.249G>T; p.K83N; 4:76022395-76022395	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.138A>G; p.E46E; 4:76022741-76022741	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.223C>T; p.L75L; 4:76022421-76022421	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.100A>G; p.S34G; 4:76022779-76022779	skin	malignant_melanoma	Substitution - Missense
c.114A>G; p.Q38Q; 4:76022765-76022765	skin	malignant_melanoma	Substitution - coding silent
c.108T>C; p.S36S; 4:76022771-76022771	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.82G>A; p.V28I; 4:76022797-76022797	breast	carcinoma	Substitution - Missense
c.279G>A; p.R93R; 4:76021948-76021948	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.279G>A; p.R93R; 4:76021948-76021948	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.279G>A; p.R93R; 4:76021948-76021948	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.279G>A; p.R93R; 4:76021948-76021948	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.279G>A; p.R93R; 4:76021948-76021948	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.237G>A; p.S79S; 4:76022407-76022407	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.273G>A; p.K91K; 4:76022371-76022371	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.22A>G; p.I8V; 4:76023410-76023410	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.23T>C; p.I8T; 4:76023409-76023409	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.178G>A; p.V60I; 4:76022701-76022701	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.236C>T; p.S79L; 4:76022408-76022408	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.42G>A; p.L14L; 4:76023390-76023390	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.236C>T; p.S79L; 4:76022408-76022408	skin	malignant_melanoma	Substitution - Missense
c.279G>T; p.R93S; 4:76021948-76021948	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.279G>T; p.R93S; 4:76021948-76021948	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.279G>T; p.R93S; 4:76021948-76021948	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.279G>T; p.R93S; 4:76021948-76021948	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.279G>T; p.R93S; 4:76021948-76021948	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.279G>T; p.R93S; 4:76021948-76021948	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.279G>T; p.R93S; 4:76021948-76021948	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.279G>T; p.R93S; 4:76021948-76021948	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.292C>T; p.P98S; 4:76021935-76021935	skin	malignant_melanoma	Substitution - Missense
c.275A>T; p.E92V; 4:76022369-76022369	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.69T>A; p.P23P; 4:76022810-76022810	pancreas	carcinoma	Substitution - coding silent
c.61G>A; p.G21R; 4:76023371-76023371	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.279G>C; p.R93S; 4:76021948-76021948	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense

COSMIC somatic mutation [Top]