| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3623 |
Name | INHA |
Synonymous | inhibin, alpha;INHA;inhibin, alpha |
Definition | A-inhibin subunit|inhibin alpha chain |
Position | 2q35 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.488T>A; p.V163E; 2:219574913-219574913 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.921C>T; p.V307V; 2:219575346-219575346 |
skin | malignant_melanoma | Substitution - coding silent |
c.704C>T; p.P235L; 2:219575129-219575129 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.823G>T; p.G275C; 2:219575248-219575248 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.695G>A; p.R232H; 2:219575120-219575120 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.431C>A; p.A144D; 2:219574856-219574856 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.969G>A; p.G323G; 2:219575394-219575394 |
skin | malignant_melanoma | Substitution - coding silent |
c.1005G>A; p.M335I; 2:219575430-219575430 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.917C>T; p.P306L; 2:219575342-219575342 |
skin | malignant_melanoma | Substitution - Missense |
c.365G>A; p.R122H; 2:219574790-219574790 |
pancreas | carcinoma | Substitution - Missense |
c.120C>A; p.A40A; 2:219572494-219572494 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.914T>G; p.L305R; 2:219575339-219575339 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.874C>A; p.H292N; 2:219575299-219575299 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.874C>A; p.H292N; 2:219575299-219575299 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.174G>A; p.L58L; 2:219572548-219572548 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.846C>T; p.Y282Y; 2:219575271-219575271 |
skin | malignant_melanoma | Substitution - coding silent |
c.554C>G; p.A185G; 2:219574979-219574979 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.632C>T; p.A211V; 2:219575057-219575057 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.349C>T; p.P117S; 2:219574774-219574774 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.739C>T; p.R247C; 2:219575164-219575164 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.739C>T; p.R247C; 2:219575164-219575164 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.132C>T; p.P44P; 2:219572506-219572506 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.833G>T; p.R278L; 2:219575258-219575258 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.912C>T; p.S304S; 2:219575337-219575337 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.1072C>T; p.L358F; 2:219575497-219575497 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.1036G>A; p.G346R; 2:219575461-219575461 |
skin; ear | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.182G>T; p.R61I; 2:219572556-219572556 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.290C>T; p.S97L; 2:219574715-219574715 |
oesophagus | carcinoma | Substitution - Missense |
c.837G>T; p.W279C; 2:219575262-219575262 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.716G>A; p.W239*; 2:219575141-219575141 |
prostate | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.813C>T; p.F271F; 2:219575238-219575238 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.127delC; p.A45fs*2; 2:219572501-219572501 |
large_intestine | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.127delC; p.A45fs*2; 2:219572501-219572501 |
large_intestine | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.771T>C; p.A257A; 2:219575196-219575196 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.677G>A; p.G226E; 2:219575102-219575102 |
skin | malignant_melanoma | Substitution - Missense |
c.531C>T; p.A177A; 2:219574956-219574956 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia | Substitution - coding silent |
c.531C>T; p.A177A; 2:219574956-219574956 |
thyroid | other; neoplasm | Substitution - coding silent |
c.531C>T; p.A177A; 2:219574956-219574956 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia | Substitution - coding silent |
c.88C>T; p.L30L; 2:219572462-219572462 |
skin | malignant_melanoma | Substitution - coding silent |
c.471G>A; p.L157L; 2:219574896-219574896 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.885T>G; p.C295W; 2:219575310-219575310 |
pleura | pulmonary_blastoma | Substitution - Missense |
c.714C>A; p.S238S; 2:219575139-219575139 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.782A>T; p.N261I; 2:219575207-219575207 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.449C>G; p.P150R; 2:219574874-219574874 |
breast | carcinoma | Substitution - Missense |
c.706C>G; p.L236V; 2:219575131-219575131 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.557T>C; p.L186P; 2:219574982-219574982 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.406G>A; p.G136R; 2:219574831-219574831 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.1046C>A; p.S349Y; 2:219575471-219575471 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.458G>T; p.G153V; 2:219574883-219574883 |
oesophagus | carcinoma | Substitution - Missense |
c.134C>T; p.A45V; 2:219572508-219572508 |
pituitary; craniopharyngeal_duct | craniopharyngioma; adamantinomatous | Substitution - Missense |
c.841G>A; p.V281M; 2:219575266-219575266 |
breast | carcinoma | Substitution - Missense |
c.304C>T; p.L102L; 2:219574729-219574729 |
skin | malignant_melanoma | Substitution - coding silent |
c.554_555delCT; p.L188fs*22; 2:219574979-219574980 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.871T>C; p.C291R; 2:219575296-219575296 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.872G>C; p.C291S; 2:219575297-219575297 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.1032G>A; p.S344S; 2:219575457-219575457 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.1022G>A; p.R341H; 2:219575447-219575447 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.604C>T; p.L202F; 2:219575029-219575029 |
skin | malignant_melanoma | Substitution - Missense |
c.694C>T; p.R232C; 2:219575119-219575119 |
upper_aerodigestive_tract; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.408G>A; p.G136G; 2:219574833-219574833 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.872G>A; p.C291Y; 2:219575297-219575297 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.923C>T; p.P308L; 2:219575348-219575348 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.636G>A; p.T212T; 2:219575061-219575061 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.553_554insCT; p.L189fs*2; 2:219574978-219574979 |
large_intestine; colon | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.553_554insCT; p.L189fs*2; 2:219574978-219574979 |
large_intestine; colon | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.1001C>T; p.T334I; 2:219575426-219575426 |
NS | malignant_melanoma | Substitution - Missense |
c.729C>T; p.P243P; 2:219575154-219575154 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.807_809delCTC; p.S270delS; 2:219575232-219575234 |
oesophagus; middle_third | carcinoma; squamous_cell_carcinoma | Deletion - In frame |
c.126G>C; p.G42G; 2:219572500-219572500 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.512A>G; p.H171R; 2:219574937-219574937 |
NS | malignant_melanoma | Substitution - Missense |
c.512A>G; p.H171R; 2:219574937-219574937 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; hairy_cell_leukaemia | Substitution - Missense |
c.126G>C; p.G42G; 2:219572500-219572500 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.512A>G; p.H171R; 2:219574937-219574937 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; hairy_cell_leukaemia | Substitution - Missense |
c.938C>T; p.T313I; 2:219575363-219575363 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Substitution - Missense |
c.1027A>C; p.T343P; 2:219575452-219575452 |
breast | carcinoma | Substitution - Missense |
c.133G>A; p.A45T; 2:219572507-219572507 |
breast | carcinoma | Substitution - Missense |
c.576C>T; p.P192P; 2:219575001-219575001 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.371G>T; p.R124L; 2:219574796-219574796 |
pancreas | carcinoma | Substitution - Missense |
c.850C>G; p.P284A; 2:219575275-219575275 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.576C>A; p.P192P; 2:219575001-219575001 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |