Entrez Gene

Basic Information
Gene ID	3598
Name	IL13RA2
Synonymous	interleukin 13 receptor, alpha 2;IL13RA2;interleukin 13 receptor, alpha 2
Definition	IL-13 receptor subunit alpha-2\|IL-13R subunit alpha-2\|IL-13R-alpha-2\|IL-13RA2\|cancer/testis antigen 19\|interleukin 13 binding protein\|interleukin 13 receptor alpha 2 chain\|interleukin-13 receptor subunit alpha-2\|interleukin-13-binding protein
Position	Xq23
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.607G>T; p.E203*; 23:115010743-115010743	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.824A>G; p.E275G; 23:115009549-115009549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.735T>G; p.T245T; 23:115009638-115009638	breast	carcinoma	Substitution - coding silent
c.1139C>G; p.T380R; 23:115004084-115004084	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.616G>T; p.D206Y; 23:115010734-115010734	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.188A>T; p.K63M; 23:115015728-115015728	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.130G>A; p.G44R; 23:115015786-115015786	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.317A>G; p.H106R; 23:115014504-115014504	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1100A>G; p.N367S; 23:115005213-115005213	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.194G>T; p.C65F; 23:115015722-115015722	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.817G>A; p.E273K; 23:115009556-115009556	skin; trunk	malignant_melanoma	Substitution - Missense
c.377C>A; p.T126N; 23:115014444-115014444	kidney	other; neoplasm	Substitution - Missense
c.1096C>A; p.P366T; 23:115005217-115005217	breast	carcinoma	Substitution - Missense
c.309G>A; p.A103A; 23:115014512-115014512	skin	malignant_melanoma	Substitution - coding silent
c.370G>A; p.A124T; 23:115014451-115014451	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1141T>C; p.*381R; 23:115004082-115004082	large_intestine; colon	carcinoma; adenocarcinoma	Nonstop extension
c.1123G>A; p.E375K; 23:115004100-115004100	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1123G>A; p.E375K; 23:115004100-115004100	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.618C>T; p.D206D; 23:115010732-115010732	lung	carcinoma; non_small_cell_carcinoma	Substitution - coding silent
c.104C>T; p.P35L; 23:115015812-115015812	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1128T>G; p.F376L; 23:115004095-115004095	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.582T>C; p.N194N; 23:115010768-115010768	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.786G>A; p.L262L; 23:115009587-115009587	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.786G>A; p.L262L; 23:115009587-115009587	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.887A>C; p.K296T; 23:115008042-115008042	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1061T>C; p.L354S; 23:115005252-115005252	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.881C>T; p.T294I; 23:115008048-115008048	breast	carcinoma	Substitution - Missense
c.29G>A; p.C10Y; 23:115017241-115017241	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.630C>T; p.F210F; 23:115010720-115010720	NS	NS	Substitution - coding silent
c.985C>A; p.Q329K; 23:115007944-115007944	breast	carcinoma	Substitution - Missense
c.942T>G; p.I314M; 23:115007987-115007987	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.247-1G>A; p.?; 23:115014575-115014575	stomach	carcinoma; adenocarcinoma	Unknown
c.1045_1046GG>AA; p.G349N; 23:115005267-115005268	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.618C>A; p.D206E; 23:115010732-115010732	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.904C>G; p.R302G; 23:115008025-115008025	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.36T>G; p.Y12*; 23:115017234-115017234	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Nonsense
c.429G>A; p.M143I; 23:115013861-115013861	skin	malignant_melanoma	Substitution - Missense
c.782C>A; p.P261H; 23:115009591-115009591	skin	malignant_melanoma	Substitution - Missense
c.429G>A; p.M143I; 23:115013861-115013861	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.230G>C; p.G77A; 23:115015686-115015686	breast	carcinoma	Substitution - Missense
c.448T>C; p.W150R; 23:115013842-115013842	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.828C>A; p.I276I; 23:115009545-115009545	bone; femur	chondrosarcoma	Substitution - coding silent
c.332G>T; p.W111L; 23:115014489-115014489	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.925A>G; p.R309G; 23:115008004-115008004	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.915C>T; p.C305C; 23:115008014-115008014	breast	carcinoma	Substitution - coding silent
c.617A>T; p.D206V; 23:115010733-115010733	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.617A>T; p.D206V; 23:115010733-115010733	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1011G>A; p.S337S; 23:115005302-115005302	skin	malignant_melanoma	Substitution - coding silent
c.1011G>A; p.S337S; 23:115005302-115005302	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1011G>A; p.S337S; 23:115005302-115005302	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.580A>T; p.N194Y; 23:115010770-115010770	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1011G>A; p.S337S; 23:115005302-115005302	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1011G>A; p.S337S; 23:115005302-115005302	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.975G>T; p.W325C; 23:115007954-115007954	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.581A>G; p.N194S; 23:115010769-115010769	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.581A>G; p.N194S; 23:115010769-115010769	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.598C>T; p.P200S; 23:115010752-115010752	skin	malignant_melanoma	Substitution - Missense
c.361A>C; p.S121R; 23:115014460-115014460	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.95-2A>T; p.?; 23:115015823-115015823	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.346G>T; p.G116*; 23:115014475-115014475	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.625G>A; p.D209N; 23:115010725-115010725	skin; leg	malignant_melanoma	Substitution - Missense
c.625G>A; p.D209N; 23:115010725-115010725	skin; leg	malignant_melanoma	Substitution - Missense
c.538C>T; p.H180Y; 23:115010812-115010812	skin; trunk	malignant_melanoma	Substitution - Missense
c.967A>G; p.S323G; 23:115007962-115007962	breast	carcinoma	Substitution - Missense
c.1024C>A; p.L342I; 23:115005289-115005289	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1090C>T; p.R364C; 23:115005223-115005223	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.871G>A; p.E291K; 23:115008058-115008058	skin	malignant_melanoma	Substitution - Missense
c.952G>A; p.D318N; 23:115007977-115007977	skin	malignant_melanoma	Substitution - Missense
c.1091G>A; p.R364H; 23:115005222-115005222	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.599C>T; p.P200L; 23:115010751-115010751	skin	malignant_melanoma	Substitution - Missense
c.1125A>C; p.E375D; 23:115004098-115004098	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1078G>T; p.G360C; 23:115005235-115005235	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.355G>T; p.V119F; 23:115014466-115014466	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.365C>T; p.S122F; 23:115014456-115014456	skin	malignant_melanoma	Substitution - Missense
c.221G>A; p.R74Q; 23:115015695-115015695	skin	malignant_melanoma	Substitution - Missense
c.221G>A; p.R74Q; 23:115015695-115015695	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.221G>A; p.R74Q; 23:115015695-115015695	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.9C>T; p.F3F; 23:115017261-115017261	skin	malignant_melanoma	Substitution - coding silent
c.9C>T; p.F3F; 23:115017261-115017261	skin	malignant_melanoma	Substitution - coding silent
c.9C>T; p.F3F; 23:115017261-115017261	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.9C>T; p.F3F; 23:115017261-115017261	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.625G>T; p.D209Y; 23:115010725-115010725	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.131G>T; p.G44V; 23:115015785-115015785	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.818A>T; p.E273V; 23:115009555-115009555	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.457T>A; p.L153I; 23:115013833-115013833	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.617A>G; p.D206G; 23:115010733-115010733	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.617A>G; p.D206G; 23:115010733-115010733	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.617A>G; p.D206G; 23:115010733-115010733	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.617A>G; p.D206G; 23:115010733-115010733	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1007T>C; p.L336P; 23:115005306-115005306	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.435C>T; p.C145C; 23:115013855-115013855	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.308C>T; p.A103V; 23:115014513-115014513	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.591C>T; p.C197C; 23:115010759-115010759	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.34T>C; p.Y12H; 23:115017236-115017236	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1028G>A; p.R343H; 23:115005285-115005285	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.999T>G; p.G333G; 23:115005314-115005314	skin	malignant_melanoma	Substitution - coding silent
c.165C>A; p.P55P; 23:115015751-115015751	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.896A>G; p.N299S; 23:115008033-115008033	oesophagus	carcinoma	Substitution - Missense
c.1077C>T; p.T359T; 23:115005236-115005236	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1032C>G; p.F344L; 23:115005281-115005281	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1116+4A>T; p.?; 23:115005193-115005193	oesophagus; lower_third	carcinoma; adenocarcinoma	Unknown
c.219C>A; p.Y73*; 23:115015697-115015697	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.202G>C; p.E68Q; 23:115015714-115015714	breast	carcinoma	Substitution - Missense
c.652T>G; p.S218A; 23:115010698-115010698	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.971A>G; p.E324G; 23:115007958-115007958	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.265C>G; p.L89V; 23:115014556-115014556	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.719C>T; p.P240L; 23:115009654-115009654	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]