| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3316 |
Name | HSPB2 |
Synonymous | heat shock 27kDa protein 2;HSPB2;heat shock 27kDa protein 2 |
Definition | DMPK-binding protein|heat shock protein beta-2|heat-shock protein beta-2 |
Position | 11q22-q23 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.463A>G; p.T155A; 11:111913809-111913809 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.341_342CC>TT; p.S114F; 11:111913687-111913688 |
upper_aerodigestive_tract; mouth | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.131A>T; p.Y44F; 11:111913477-111913477 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.131A>T; p.Y44F; 11:111913477-111913477 |
urinary_tract; bladder | carcinoma; transitional_cell_carcinoma | Substitution - Missense |
c.29A>T; p.H10L; 11:111912858-111912858 |
liver | carcinoma; hepatocellular_carcinoma | Substitution - Missense |
c.258C>T; p.D86D; 11:111913604-111913604 |
bone | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Substitution - coding silent |
c.199C>T; p.L67F; 11:111913545-111913545 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.119delC; p.T42fs*39; 11:111913465-111913465 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.342C>A; p.S114S; 11:111913688-111913688 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.286C>A; p.L96M; 11:111913632-111913632 |
large_intestine; colon | adenoma | Substitution - Missense |
c.471C>T; p.V157V; 11:111913817-111913817 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - coding silent |
c.449G>A; p.G150D; 11:111913795-111913795 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.138C>T; p.G46G; 11:111913484-111913484 |
oesophagus | carcinoma; adenocarcinoma | Substitution - coding silent |
c.325C>T; p.R109C; 11:111913671-111913671 |
oesophagus | carcinoma | Substitution - Missense |
c.11G>A; p.R4H; 11:111912840-111912840 |
liver | carcinoma | Substitution - Missense |
c.11G>A; p.R4H; 11:111912840-111912840 |
liver | carcinoma | Substitution - Missense |
c.397C>T; p.R133*; 11:111913743-111913743 |
pancreas | carcinoma | Substitution - Nonsense |
c.441T>A; p.P147P; 11:111913787-111913787 |
skin | malignant_melanoma | Substitution - coding silent |
c.514G>A; p.E172K; 11:111913860-111913860 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.340T>C; p.S114P; 11:111913686-111913686 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.460G>C; p.D154H; 11:111913806-111913806 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.460G>C; p.D154H; 11:111913806-111913806 |
urinary_tract; bladder | carcinoma; transitional_cell_carcinoma | Substitution - Missense |
c.391C>T; p.R131*; 11:111913737-111913737 |
ovary | other; neoplasm | Substitution - Nonsense |
c.439C>G; p.P147A; 11:111913785-111913785 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.155G>T; p.R52L; 11:111913501-111913501 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.312C>T; p.P104P; 11:111913658-111913658 |
skin | malignant_melanoma | Substitution - coding silent |
c.440C>A; p.P147H; 11:111913786-111913786 |
stomach | adenocarcinoma | Substitution - Missense |
c.196G>A; p.E66K; 11:111913542-111913542 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.214G>T; p.G72C; 11:111913560-111913560 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.380T>A; p.V127D; 11:111913726-111913726 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.317G>A; p.R106H; 11:111913663-111913663 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.179G>A; p.S60N; 11:111913525-111913525 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.37A>G; p.T13A; 11:111912866-111912866 |
pancreas | carcinoma | Substitution - Missense |
c.179G>A; p.S60N; 11:111913525-111913525 |
urinary_tract; bladder | carcinoma; transitional_cell_carcinoma | Substitution - Missense |
c.194C>A; p.S65Y; 11:111913540-111913540 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.342C>T; p.S114S; 11:111913688-111913688 |
skin | malignant_melanoma | Substitution - coding silent |
c.391C>A; p.R131R; 11:111913737-111913737 |
ovary | carcinoma; serous_carcinoma | Substitution - coding silent |
c.391C>A; p.R131R; 11:111913737-111913737 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |