Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

3293

Name

HSD17B3

Synonymous

hydroxysteroid (17-beta) dehydrogenase 3;HSD17B3;hydroxysteroid (17-beta) dehydrogenase 3

Definition

17-beta-HSD 3|17-beta-HSD3|17-beta-hydroxysteroid dehydrogenase type 3|short chain dehydrogenase/reductase family 12C member 2|short chain dehydrogenase/reductase family 12C, member 2|testicular 17-beta-hydroxysteroid dehydrogenase|testosterone 17-beta-de

Position

9q22

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.10G>A; p.V4I; 9:96302095-96302095

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.858C>G; p.F286L; 9:96235535-96235535

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.554C>T; p.S185F; 9:96245397-96245397

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.554C>T; p.S185F; 9:96245397-96245397

 thyroidother; neoplasmSubstitution - Missense

c.554C>T; p.S185F; 9:96245397-96245397

 skinmalignant_melanomaSubstitution - Missense

c.571C>T; p.P191S; 9:96245380-96245380

 skinmalignant_melanomaSubstitution - Missense

c.15G>A; p.L5L; 9:96302090-96302090

 skinmalignant_melanomaSubstitution - coding silent

c.254T>C; p.L85P; 9:96254891-96254891

 thyroidcarcinomaSubstitution - Missense

c.814G>A; p.E272K; 9:96240766-96240766

 skinmalignant_melanomaSubstitution - Missense

c.517G>A; p.E173K; 9:96246563-96246563

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.191A>G; p.Y64C; 9:96298426-96298426

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.456C>A; p.S152R; 9:96249784-96249784

 breastcarcinomaSubstitution - Missense

c.357A>T; p.K119N; 9:96252831-96252831

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.181G>T; p.G61W; 9:96298436-96298436

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.91G>A; p.V31I; 9:96302014-96302014

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.181G>T; p.G61W; 9:96298436-96298436

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.521C>G; p.S174*; 9:96246559-96246559

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.406C>T; p.P136S; 9:96251465-96251465

 skinmalignant_melanomaSubstitution - Missense

c.627C>G; p.S209S; 9:96244374-96244374

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.189G>A; p.A63A; 9:96298428-96298428

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.696G>A; p.S232S; 9:96240884-96240884

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.282G>A; p.R94R; 9:96252906-96252906

 skinmalignant_melanomaSubstitution - coding silent

c.865G>A; p.G289S; 9:96235528-96235528

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.676C>T; p.L226L; 9:96240904-96240904

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.793A>G; p.T265A; 9:96240787-96240787

 prostatecarcinomaSubstitution - Missense

c.454-1G>A; p.?; 9:96249787-96249787

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.286A>G; p.T96A; 9:96252902-96252902

 bone; extraskeletalEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.776T>C; p.V259A; 9:96240804-96240804

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.630G>A; p.K210K; 9:96244371-96244371

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.799G>A; p.G267S; 9:96240781-96240781

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.276C>T; p.I92I; 9:96254869-96254869

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.66G>A; p.A22A; 9:96302039-96302039

 breastcarcinomaSubstitution - coding silent

c.194C>T; p.S65L; 9:96298423-96298423

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.66G>A; p.A22A; 9:96302039-96302039

 pancreascarcinomaSubstitution - coding silent

c.435C>T; p.N145N; 9:96251436-96251436

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.684A>G; p.P228P; 9:96240896-96240896

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.615G>T; p.V205V; 9:96244386-96244386

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.551C>A; p.S184Y; 9:96245400-96245400

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.551C>A; p.S184Y; 9:96245400-96245400

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.551C>A; p.S184Y; 9:96245400-96245400

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.450C>T; p.I150I; 9:96251421-96251421

 skinmalignant_melanomaSubstitution - coding silent

c.424C>T; p.H142Y; 9:96251447-96251447

 skinmalignant_melanomaSubstitution - Missense

c.720T>G; p.N240K; 9:96240860-96240860

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.766T>C; p.L256L; 9:96240814-96240814

 pancreascarcinoid-endocrine_tumourSubstitution - coding silent

c.201+1G>A; p.?; 9:96298415-96298415

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.108G>A; p.W36*; 9:96301997-96301997

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.210_211insA; p.R71fs*9; 9:96254934-96254935

 large_intestinecarcinoma; adenocarcinomaInsertion - Frameshift

c.445G>A; p.E149K; 9:96251426-96251426

 skinmalignant_melanomaSubstitution - Missense

c.858C>T; p.F286F; 9:96235535-96235535

 breastcarcinomaSubstitution - coding silent

c.489G>T; p.K163N; 9:96249751-96249751

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.247G>A; p.E83K; 9:96254898-96254898

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.463C>T; p.H155Y; 9:96249777-96249777

 skinmalignant_melanomaSubstitution - Missense

c.643G>A; p.E215K; 9:96244358-96244358

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.824C>T; p.A275V; 9:96235569-96235569

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.281G>A; p.R94Q; 9:96252907-96252907

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.836G>A; p.S279N; 9:96235557-96235557

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.619G>A; p.A207T; 9:96244382-96244382

 pancreascarcinomaSubstitution - Missense

c.619G>A; p.A207T; 9:96244382-96244382

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.340G>A; p.E114K; 9:96252848-96252848

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.846G>A; p.P282P; 9:96235547-96235547

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.64G>A; p.A22T; 9:96302041-96302041

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.201+4A>T; p.?; 9:96298412-96298412

 lungcarcinoma; adenocarcinomaUnknown

c.117G>A; p.L39L; 9:96301988-96301988

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.462C>T; p.I154I; 9:96249778-96249778

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.658G>T; p.E220*; 9:96244343-96244343

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.658G>T; p.E220*; 9:96244343-96244343

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.808G>A; p.A270T; 9:96240772-96240772

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.167C>T; p.A56V; 9:96298450-96298450

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.844C>T; p.P282S; 9:96235549-96235549

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.167C>T; p.A56V; 9:96298450-96298450

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense