| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3224 |
Name | HOXC8 |
Synonymous | homeobox C8;HOXC8;homeobox C8 |
Definition | Hox-3.1, mouse, homolog of|homeo box 3A|homeo box C8|homeobox protein Hox-3A|homeobox protein Hox-C8 |
Position | 12q13.3 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.665T>G; p.V222G; 12:54011317-54011317 |
breast | carcinoma | Substitution - Missense |
c.60A>G; p.E20E; 12:54009344-54009344 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.318G>A; p.A106A; 12:54009602-54009602 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.441delG; p.R149fs*16; 12:54011093-54011093 |
large_intestine; caecum | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.201C>A; p.I67I; 12:54009485-54009485 |
prostate | carcinoma; adenocarcinoma | Substitution - coding silent |
c.177C>G; p.F59L; 12:54009461-54009461 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.514C>T; p.P172S; 12:54011166-54011166 |
skin; face | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.435C>A; p.H145Q; 12:54009719-54009719 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.631G>A; p.D211N; 12:54011283-54011283 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.121G>C; p.G41R; 12:54009405-54009405 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.93C>A; p.S31R; 12:54009377-54009377 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.721A>C; p.K241Q; 12:54011373-54011373 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.348C>A; p.S116S; 12:54009632-54009632 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.348C>A; p.S116S; 12:54009632-54009632 |
breast | carcinoma | Substitution - coding silent |
c.373G>T; p.G125*; 12:54009657-54009657 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Nonsense |
c.627C>T; p.N209N; 12:54011279-54011279 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.45C>T; p.A15A; 12:54009329-54009329 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.227C>T; p.P76L; 12:54009511-54009511 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.264C>A; p.F88L; 12:54009548-54009548 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.264C>A; p.F88L; 12:54009548-54009548 |
oesophagus | carcinoma | Substitution - Missense |
c.80G>A; p.R27Q; 12:54009364-54009364 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; chronic_myeloid_leukaemia | Substitution - Missense |
c.507C>G; p.L169L; 12:54011159-54011159 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.80G>A; p.R27Q; 12:54009364-54009364 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; chronic_myeloid_leukaemia | Substitution - Missense |
c.458G>A; p.R153Q; 12:54011110-54011110 |
skin | malignant_melanoma | Substitution - Missense |
c.187G>C; p.G63R; 12:54009471-54009471 |
skin; leg | malignant_melanoma | Substitution - Missense |
c.153C>T; p.H51H; 12:54009437-54009437 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.677G>A; p.G226E; 12:54011329-54011329 |
skin; trunk | malignant_melanoma | Substitution - Missense |
c.440C>T; p.P147L; 12:54011092-54011092 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.312A>G; p.Q104Q; 12:54009596-54009596 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia | Substitution - coding silent |
c.548C>T; p.S183F; 12:54011200-54011200 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.548C>T; p.S183F; 12:54011200-54011200 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.493_494insA; p.E167fs*5; 12:54011145-54011146 |
large_intestine; caecum | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.514C>G; p.P172A; 12:54011166-54011166 |
ovary | other; neoplasm | Substitution - Missense |
c.514C>G; p.P172A; 12:54011166-54011166 |
ovary | other; neoplasm | Substitution - Missense |
c.332A>G; p.Y111C; 12:54009616-54009616 |
liver | carcinoma | Substitution - Missense |
c.332A>G; p.Y111C; 12:54009616-54009616 |
liver | carcinoma | Substitution - Missense |
c.560G>A; p.G187E; 12:54011212-54011212 |
urinary_tract; bladder | carcinoma; transitional_cell_carcinoma | Substitution - Missense |
c.560G>A; p.G187E; 12:54011212-54011212 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.581A>T; p.K194M; 12:54011233-54011233 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.651A>C; p.R217R; 12:54011303-54011303 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.436G>A; p.A146T; 12:54009720-54009720 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.712G>A; p.E238K; 12:54011364-54011364 |
skin | malignant_melanoma | Substitution - Missense |