Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

3218

Name

HOXB8

Synonymous

homeobox B8;HOXB8;homeobox B8

Definition

homeo box 2D|homeo box B8|homeobox protein Hox-2.4|homeobox protein Hox-2D|homeobox protein Hox-B8

Position

17q21.3

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.385C>T; p.P129S; 17:48614320-48614320

 skinmalignant_melanomaSubstitution - Missense

c.708C>A; p.D236E; 17:48613226-48613226

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.678G>T; p.E226D; 17:48613256-48613256

 breastcarcinomaSubstitution - Missense

c.226G>A; p.V76M; 17:48614479-48614479

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.476T>C; p.L159P; 17:48613458-48613458

 bone; ribchondrosarcomaSubstitution - Missense

c.458A>G; p.Y153C; 17:48613476-48613476

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.320A>G; p.Y107C; 17:48614385-48614385

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.356G>A; p.G119D; 17:48614349-48614349

 skinmalignant_melanomaSubstitution - Missense

c.47G>C; p.G16A; 17:48614658-48614658

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.381G>C; p.Q127H; 17:48614324-48614324

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.15C>T; p.F5F; 17:48614690-48614690

 skinmalignant_melanomaSubstitution - coding silent

c.15C>T; p.F5F; 17:48614690-48614690

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.711G>T; p.A237A; 17:48613223-48613223

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.203C>T; p.P68L; 17:48614502-48614502

 central_nervous_system; braingliomaSubstitution - Missense

c.357C>T; p.G119G; 17:48614348-48614348

 biliary_tract; bile_ductcarcinoma; adenocarcinomaSubstitution - coding silent

c.264C>T; p.Y88Y; 17:48614441-48614441

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.219G>A; p.P73P; 17:48614486-48614486

 pancreascarcinomaSubstitution - coding silent

c.540G>A; p.S180S; 17:48613394-48613394

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.367G>A; p.E123K; 17:48614338-48614338

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.563G>C; p.R188T; 17:48613371-48613371

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.367G>A; p.E123K; 17:48614338-48614338

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.367G>A; p.E123K; 17:48614338-48614338

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.371G>A; p.G124D; 17:48614334-48614334

 pancreascarcinoma; ductal_carcinomaSubstitution - Missense

c.222C>T; p.C74C; 17:48614483-48614483

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.699C>A; p.D233E; 17:48613235-48613235

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.302A>G; p.D101G; 17:48614403-48614403

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.258C>T; p.Y86Y; 17:48614447-48614447

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.726G>A; p.K242K; 17:48613208-48613208

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.94C>A; p.L32M; 17:48614611-48614611

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.352C>A; p.L118M; 17:48614353-48614353

 pancreascarcinomaSubstitution - Missense

c.111C>T; p.T37T; 17:48614594-48614594

 skinmalignant_melanomaSubstitution - coding silent

c.469C>A; p.Q157K; 17:48613465-48613465

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.186G>A; p.S62S; 17:48614519-48614519

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.550G>A; p.G184R; 17:48613384-48613384

 skinmalignant_melanomaSubstitution - Missense

c.727A>C; p.K243Q; 17:48613207-48613207

 skinmalignant_melanomaSubstitution - Missense

c.89A>C; p.Q30P; 17:48614616-48614616

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.133G>T; p.G45C; 17:48614572-48614572

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.16G>A; p.V6I; 17:48614689-48614689

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.662A>T; p.E221V; 17:48613272-48613272

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.321C>T; p.Y107Y; 17:48614384-48614384

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.85_93delGCCCAGGAC; p.A29_D31delAQD; 17:48614612-48614620

 urinary_tract; bladdercarcinomaDeletion - In frame

c.6C>A; p.S2R; 17:48614699-48614699

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.657G>T; p.E219D; 17:48613277-48613277

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.663G>T; p.E221D; 17:48613271-48613271

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.506C>A; p.P169H; 17:48613428-48613428

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.710C>A; p.A237E; 17:48613224-48613224

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.375C>T; p.S125S; 17:48614330-48614330

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.498A>G; p.L166L; 17:48613436-48613436

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.271C>A; p.L91M; 17:48614434-48614434

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.419C>T; p.P140L; 17:48614286-48614286

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.257A>G; p.Y86C; 17:48614448-48614448

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.257A>G; p.Y86C; 17:48614448-48614448

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.421C>T; p.Q141*; 17:48614284-48614284

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.223G>T; p.A75S; 17:48614482-48614482

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense