Entrez Gene

Basic Information
Gene ID	3161
Name	HMMR
Synonymous	hyaluronan-mediated motility receptor (RHAMM);HMMR;hyaluronan-mediated motility receptor (RHAMM)
Definition	hyaluronan mediated motility receptor\|intracellular hyaluronic acid-binding protein\|receptor for hyaluronan-mediated motility
Position	5q34
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.2019A>G; p.Q673Q; 5:163490449-163490449	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1655G>C; p.R552T; 5:163483145-163483145	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.661A>G; p.K221E; 5:163473192-163473192	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1753G>A; p.E585K; 5:163483338-163483338	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1689T>A; p.A563A; 5:163483274-163483274	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.671T>G; p.I224S; 5:163473202-163473202	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.387C>A; p.L129L; 5:163469757-163469757	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1647A>T; p.E549D; 5:163483137-163483137	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1647A>T; p.E549D; 5:163483137-163483137	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.349G>T; p.A117S; 5:163469719-163469719	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2134T>G; p.C712G; 5:163491123-163491123	liver	carcinoma	Substitution - Missense
c.1556C>G; p.S519*; 5:163483046-163483046	pancreas	carcinoma	Substitution - Nonsense
c.2134T>G; p.C712G; 5:163491123-163491123	liver	carcinoma	Substitution - Missense
c.1556C>G; p.S519*; 5:163483046-163483046	pancreas	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.15G>A; p.K5K; 5:163460707-163460707	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.435G>T; p.R145S; 5:163469805-163469805	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.564A>C; p.Q188H; 5:163471380-163471380	skin	malignant_melanoma	Substitution - Missense
c.2122+2T>C; p.?; 5:163490554-163490554	large_intestine; rectum	carcinoma; adenocarcinoma	Unknown
c.1815_1816GG>TT; p.Q605_A606>HS; 5:163484101-163484102	lung; right_lower_lobe	carcinoma; adenocarcinoma	Complex - compound substitution
c.146-1G>A; p.?; 5:163464722-163464722	breast	carcinoma	Unknown
c.334T>C; p.L112L; 5:163469704-163469704	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1266G>T; p.G422G; 5:163478684-163478684	breast	carcinoma	Substitution - coding silent
c.82A>G; p.T28A; 5:163463891-163463891	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1987G>T; p.A663S; 5:163490417-163490417	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	oesophagus; lower_third	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1990delA; p.K666fs*11; 5:163490420-163490420	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1947C>T; p.S649S; 5:163484233-163484233	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1990delA; p.K666fs*11; 5:163490420-163490420	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2067G>T; p.K689N; 5:163490497-163490497	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.708C>A; p.Y236*; 5:163473239-163473239	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.708C>A; p.Y236*; 5:163473239-163473239	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.960C>G; p.N320K; 5:163474115-163474115	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.750C>A; p.Y250*; 5:163473406-163473406	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1125G>A; p.E375E; 5:163475532-163475532	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1516C>G; p.Q506E; 5:163482775-163482775	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2116A>G; p.K706E; 5:163490546-163490546	skin	malignant_melanoma	Substitution - Missense
c.2138A>G; p.Y713C; 5:163491127-163491127	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.940C>A; p.L314I; 5:163474095-163474095	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.305A>G; p.D102G; 5:163469675-163469675	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.901G>T; p.E301*; 5:163473557-163473557	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1548G>C; p.Q516H; 5:163483038-163483038	breast	carcinoma	Substitution - Missense
c.1223C>T; p.S408F; 5:163475630-163475630	skin	malignant_melanoma	Substitution - Missense
c.230C>A; p.S77Y; 5:163467708-163467708	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.788A>C; p.E263A; 5:163473444-163473444	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.939T>C; p.N313N; 5:163474094-163474094	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1085C>T; p.S362F; 5:163475492-163475492	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.804T>G; p.I268M; 5:163473460-163473460	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1595C>A; p.S532Y; 5:163483085-163483085	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1453G>A; p.A485T; 5:163482712-163482712	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1451C>T; p.A484V; 5:163482710-163482710	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.816G>A; p.K272K; 5:163473472-163473472	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.665A>G; p.E222G; 5:163473196-163473196	ovary	other; neoplasm	Substitution - Missense
c.1078C>T; p.L360F; 5:163475485-163475485	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1090C>T; p.Q364*; 5:163475497-163475497	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2143G>T; p.A715S; 5:163491132-163491132	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.292C>T; p.R98C; 5:163469662-163469662	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1738C>T; p.R580C; 5:163483323-163483323	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1738C>T; p.R580C; 5:163483323-163483323	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.569G>A; p.G190D; 5:163471385-163471385	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1739G>A; p.R580H; 5:163483324-163483324	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1739G>A; p.R580H; 5:163483324-163483324	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1129G>T; p.E377*; 5:163475536-163475536	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1460C>A; p.A487D; 5:163482719-163482719	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.237G>A; p.K79K; 5:163467715-163467715	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.667A>C; p.K223Q; 5:163473198-163473198	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.374delA; p.T127fs*17; 5:163469744-163469744	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.374delA; p.T127fs*17; 5:163469744-163469744	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1103T>C; p.V368A; 5:163475510-163475510	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1103T>C; p.V368A; 5:163475510-163475510	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1103T>C; p.V368A; 5:163475510-163475510	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1103T>C; p.V368A; 5:163475510-163475510	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1103T>C; p.V368A; 5:163475510-163475510	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1723G>T; p.E575*; 5:163483308-163483308	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.385C>A; p.L129I; 5:163469755-163469755	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.683C>A; p.S228Y; 5:163473214-163473214	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.1990_1991delAA; p.K666fs*3; 5:163490420-163490421	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.607G>A; p.E203K; 5:163471423-163471423	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.607G>A; p.E203K; 5:163471423-163471423	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.607G>A; p.E203K; 5:163471423-163471423	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1036C>A; p.L346M; 5:163474191-163474191	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.294T>A; p.R98R; 5:163469664-163469664	kidney	other; neoplasm	Substitution - coding silent
c.1548G>A; p.Q516Q; 5:163483038-163483038	breast	carcinoma	Substitution - coding silent
c.1557A>G; p.S519S; 5:163483047-163483047	skin	malignant_melanoma	Substitution - coding silent
c.216G>A; p.S72S; 5:163464793-163464793	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.373_374insA; p.T127fs*7; 5:163469743-163469744	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.247G>T; p.D83Y; 5:163467725-163467725	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1457A>T; p.K486M; 5:163482716-163482716	breast	carcinoma	Substitution - Missense
c.1559C>A; p.A520E; 5:163483049-163483049	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1967C>G; p.S656*; 5:163490397-163490397	oesophagus	carcinoma	Substitution - Nonsense
c.2108C>T; p.T703I; 5:163490538-163490538	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1401C>T; p.A467A; 5:163482660-163482660	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1563A>G; p.L521L; 5:163483053-163483053	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.346G>C; p.E116Q; 5:163469716-163469716	ovary	other; neoplasm	Substitution - Missense
c.1260G>A; p.L420L; 5:163475667-163475667	cervix	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.867A>G; p.L289L; 5:163473523-163473523	prostate	carcinoma	Substitution - coding silent
c.709A>G; p.I237V; 5:163473240-163473240	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.933C>T; p.N311N; 5:163474088-163474088	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1485G>T; p.Q495H; 5:163482744-163482744	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.553A>G; p.M185V; 5:163471369-163471369	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1238T>C; p.L413S; 5:163475645-163475645	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1884A>G; p.L628L; 5:163484170-163484170	skin	malignant_melanoma	Substitution - coding silent
c.1234G>A; p.E412K; 5:163475641-163475641	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.699C>T; p.L233L; 5:163473230-163473230	skin	malignant_melanoma	Substitution - coding silent
c.993A>G; p.E331E; 5:163474148-163474148	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.725G>A; p.C242Y; 5:163473381-163473381	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1436C>T; p.S479L; 5:163482695-163482695	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.701T>G; p.L234W; 5:163473232-163473232	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.375A>G; p.E125E; 5:163469745-163469745	oesophagus; upper_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1329A>G; p.E443E; 5:163478747-163478747	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.854A>T; p.Q285L; 5:163473510-163473510	pancreas	carcinoma	Substitution - Missense
c.754C>T; p.L252L; 5:163473410-163473410	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]