Entrez Gene

Basic Information
Gene ID	27022
Name	FOXD3
Synonymous	forkhead box D3;FOXD3;forkhead box D3
Definition	HNF3/FH transcription factor genesis\|forkhead box protein D3
Position	1p31.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.625C>A; p.P209T; 1:63323683-63323683	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.495C>G; p.S165R; 1:63323553-63323553	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.434C>G; p.S145W; 1:63323492-63323492	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.744G>T; p.Q248H; 1:63323802-63323802	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.568C>T; p.R190C; 1:63323626-63323626	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.490C>T; p.L164L; 1:63323548-63323548	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.544T>G; p.F182V; 1:63323602-63323602	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1191C>T; p.G397G; 1:63324249-63324249	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.562A>C; p.S188R; 1:63323620-63323620	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.222C>A; p.P74P; 1:63323280-63323280	thyroid	other; neoplasm	Substitution - coding silent
c.222C>A; p.P74P; 1:63323280-63323280	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.222C>A; p.P74P; 1:63323280-63323280	thyroid	other; neoplasm	Substitution - coding silent
c.151C>T; p.P51S; 1:63323209-63323209	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.435G>A; p.S145S; 1:63323493-63323493	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.754A>G; p.M252V; 1:63323812-63323812	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1405_1406insC; p.A470fs*>10; 1:63324463-63324464	skin	malignant_melanoma	Insertion - Frameshift
c.378G>T; p.S126S; 1:63323436-63323436	ovary	other; neoplasm	Substitution - coding silent
c.806G>T; p.G269V; 1:63323864-63323864	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.694C>A; p.R232R; 1:63323752-63323752	pancreas	carcinoma	Substitution - coding silent
c.477G>A; p.Q159Q; 1:63323535-63323535	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.477G>A; p.Q159Q; 1:63323535-63323535	breast	carcinoma	Substitution - coding silent
c.76G>A; p.D26N; 1:63323134-63323134	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.536G>A; p.R179K; 1:63323594-63323594	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.88G>A; p.E30K; 1:63323146-63323146	breast	carcinoma	Substitution - Missense
c.364G>A; p.A122T; 1:63323422-63323422	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.379G>A; p.A127T; 1:63323437-63323437	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1239G>A; p.A413A; 1:63324297-63324297	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.132C>T; p.C44C; 1:63323190-63323190	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.769G>A; p.G257S; 1:63323827-63323827	pancreas	carcinoma	Substitution - Missense
c.141C>T; p.P47P; 1:63323199-63323199	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.762G>C; p.Q254H; 1:63323820-63323820	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.396G>A; p.P132P; 1:63323454-63323454	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.500T>A; p.I167N; 1:63323558-63323558	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.377C>T; p.S126L; 1:63323435-63323435	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]