| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 26269 |
Name | FBXO8 |
Synonymous | F-box protein 8;FBXO8;F-box protein 8 |
Definition | F-box only protein 8|F-box protein Fbx8|F-box/SEC7 protein FBS |
Position | 4q34.1 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.568G>A; p.D190N; 4:174241107-174241107 |
kidney | other; neoplasm | Substitution - Missense |
c.430C>T; p.L144F; 4:174259725-174259725 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.289G>A; p.V97I; 4:174262804-174262804 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.746T>C; p.L249S; 4:174239020-174239020 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.669C>G; p.A223A; 4:174239097-174239097 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - coding silent |
c.547A>G; p.K183E; 4:174241128-174241128 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.130C>A; p.R44S; 4:174262963-174262963 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.130C>A; p.R44S; 4:174262963-174262963 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.893_894insA; p.N298fs*3; 4:174237478-174237479 |
large_intestine; caecum | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.457-5C>T; p.?; 4:174241223-174241223 |
lung | carcinoma; squamous_cell_carcinoma | Unknown |
c.656G>A; p.R219H; 4:174239110-174239110 |
oesophagus | carcinoma; adenocarcinoma | Substitution - Missense |
c.374A>G; p.N125S; 4:174259781-174259781 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.641T>C; p.L214P; 4:174239125-174239125 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.131G>A; p.R44H; 4:174262962-174262962 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.877C>T; p.R293C; 4:174237495-174237495 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.392C>A; p.S131Y; 4:174259763-174259763 |
adrenal_gland; adrenal_gland | adrenal_cortical_carcinoma; functioning | Substitution - Missense |
c.856delA; p.R286fs*19; 4:174237516-174237516 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.868C>T; p.R290*; 4:174237504-174237504 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.868C>T; p.R290*; 4:174237504-174237504 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Nonsense |
c.868C>T; p.R290*; 4:174237504-174237504 |
skin | malignant_melanoma | Substitution - Nonsense |
c.868C>T; p.R290*; 4:174237504-174237504 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.306G>A; p.A102A; 4:174262787-174262787 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.805C>A; p.L269I; 4:174237567-174237567 |
breast | carcinoma; ductal_carcinoma | Substitution - Missense |
c.805C>A; p.L269I; 4:174237567-174237567 |
breast | carcinoma; ductal_carcinoma | Substitution - Missense |
c.805C>A; p.L269I; 4:174237567-174237567 |
breast | carcinoma; ductal_carcinoma | Substitution - Missense |
c.141C>A; p.V47V; 4:174262952-174262952 |
breast | carcinoma | Substitution - coding silent |
c.372G>T; p.K124N; 4:174259783-174259783 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.792C>T; p.C264C; 4:174237580-174237580 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.827G>A; p.S276N; 4:174237545-174237545 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.807A>T; p.L269L; 4:174237565-174237565 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.575G>A; p.R192K; 4:174241100-174241100 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.368A>G; p.N123S; 4:174259787-174259787 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.186G>A; p.S62S; 4:174262907-174262907 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.757C>A; p.L253I; 4:174239009-174239009 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.929A>G; p.N310S; 4:174237443-174237443 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.125A>G; p.N42S; 4:174262968-174262968 |
liver | carcinoma | Substitution - Missense |
c.493G>A; p.D165N; 4:174241182-174241182 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.752G>T; p.R251L; 4:174239014-174239014 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.414G>T; p.Q138H; 4:174259741-174259741 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.755A>G; p.E252G; 4:174239011-174239011 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.883G>A; p.A295T; 4:174237489-174237489 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.883G>A; p.A295T; 4:174237489-174237489 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.851C>G; p.S284*; 4:174237521-174237521 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.498G>A; p.S166S; 4:174241177-174241177 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.858G>A; p.R286R; 4:174237514-174237514 |
pancreas | carcinoma | Substitution - coding silent |
c.458delG; p.G153fs*2; 4:174241217-174241217 |
lung | carcinoma; squamous_cell_carcinoma | Deletion - Frameshift |
c.556A>G; p.R186G; 4:174241119-174241119 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.646G>T; p.E216*; 4:174239120-174239120 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.679C>T; p.R227C; 4:174239087-174239087 |
pancreas | carcinoma; ductal_carcinoma | Substitution - Missense |
c.575+8C>T; p.?; 4:174241092-174241092 |
large_intestine; colon | carcinoma; adenocarcinoma | Unknown |
c.317T>G; p.L106R; 4:174262776-174262776 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.142C>T; p.Q48*; 4:174262951-174262951 |
skin | malignant_melanoma | Substitution - Nonsense |
c.311A>T; p.D104V; 4:174262782-174262782 |
breast | carcinoma; ductal_carcinoma | Substitution - Missense |
c.880C>T; p.R294C; 4:174237492-174237492 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.518T>G; p.F173C; 4:174241157-174241157 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.182A>C; p.K61T; 4:174262911-174262911 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.158T>C; p.I53T; 4:174262935-174262935 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.141_142CC>TT; p.Q48*; 4:174262951-174262952 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Nonsense |
c.602C>A; p.T201K; 4:174239164-174239164 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.258G>A; p.L86L; 4:174262835-174262835 |
upper_aerodigestive_tract; mouth | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.375C>T; p.N125N; 4:174259780-174259780 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.330G>T; p.G110G; 4:174259825-174259825 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - coding silent |
c.330G>T; p.G110G; 4:174259825-174259825 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - coding silent |
c.204C>T; p.F68F; 4:174262889-174262889 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.343A>G; p.T115A; 4:174259812-174259812 |
liver | carcinoma | Substitution - Missense |
c.204C>T; p.F68F; 4:174262889-174262889 |
skin | malignant_melanoma | Substitution - coding silent |
c.45A>G; p.Q15Q; 4:174263048-174263048 |
prostate | carcinoma; adenocarcinoma | Substitution - coding silent |