Entrez Gene

Basic Information
Gene ID	25988
Name	HINFP
Synonymous	histone H4 transcription factor;HINFP;histone H4 transcription factor
Definition	MBD2 (methyl-CpG-binding protein)-interacting zinc finger protein\|MBD2-interacting zinc finger 1\|MBD2-interacting zinc finger protein\|histone H4 gene-specific protein HiNF-P\|histone nuclear factor P\|methyl-CpG-binding protein 2-interacting zinc finger pro
Position	11q23.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1139+1G>A; p.?; 11:119133220-119133220	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.725G>A; p.R242Q; 11:119132544-119132544	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.864T>C; p.C288C; 11:119132770-119132770	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.864T>C; p.C288C; 11:119132770-119132770	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.246C>T; p.L82L; 11:119130789-119130789	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.381C>T; p.D127D; 11:119130924-119130924	skin	malignant_melanoma	Substitution - coding silent
c.1459C>T; p.P487S; 11:119134403-119134403	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1409C>G; p.T470S; 11:119134353-119134353	bone; femur	chondrosarcoma	Substitution - Missense
c.453A>C; p.E151D; 11:119131576-119131576	liver	carcinoma	Substitution - Missense
c.453A>C; p.E151D; 11:119131576-119131576	liver	carcinoma	Substitution - Missense
c.1211A>G; p.Q404R; 11:119134155-119134155	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.96C>A; p.F32L; 11:119127040-119127040	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.96C>A; p.F32L; 11:119127040-119127040	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1220G>A; p.R407Q; 11:119134164-119134164	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.26G>A; p.R9Q; 11:119126970-119126970	urinary_tract; bladder	carcinoma	Substitution - Missense
c.209A>G; p.E70G; 11:119130752-119130752	thyroid	other; neoplasm	Substitution - Missense
c.376C>T; p.P126S; 11:119130919-119130919	skin	malignant_melanoma	Substitution - Missense
c.1037A>C; p.K346T; 11:119133117-119133117	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.376C>T; p.P126S; 11:119130919-119130919	skin; mucosal	malignant_melanoma	Substitution - Missense
c.758A>G; p.N253S; 11:119132664-119132664	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1184G>A; p.R395H; 11:119134128-119134128	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.137G>A; p.G46D; 11:119127081-119127081	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.565C>T; p.H189Y; 11:119131871-119131871	skin; trunk	malignant_melanoma	Substitution - Missense
c.208G>C; p.E70Q; 11:119130751-119130751	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1256T>C; p.L419P; 11:119134200-119134200	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.812G>A; p.R271H; 11:119132718-119132718	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.677-7A>T; p.?; 11:119132489-119132489	pancreas	carcinoma	Unknown
c.1067G>A; p.R356Q; 11:119133147-119133147	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1250C>T; p.T417M; 11:119134194-119134194	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1250C>T; p.T417M; 11:119134194-119134194	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1250C>T; p.T417M; 11:119134194-119134194	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1535C>T; p.P512L; 11:119134479-119134479	pancreas	NS	Substitution - Missense
c.1535C>T; p.P512L; 11:119134479-119134479	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.619A>T; p.M207L; 11:119131925-119131925	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.965G>A; p.S322N; 11:119132953-119132953	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.187G>T; p.E63*; 11:119130730-119130730	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.210A>G; p.E70E; 11:119130753-119130753	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.384C>A; p.H128Q; 11:119130927-119130927	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.478G>A; p.E160K; 11:119131601-119131601	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.252C>T; p.R84R; 11:119130795-119130795	skin	malignant_melanoma	Substitution - coding silent
c.304G>A; p.A102T; 11:119130847-119130847	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1129delC; p.R378fs*22; 11:119133209-119133209	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1053C>T; p.D351D; 11:119133133-119133133	pancreas	carcinoma; adenocarcinoma	Substitution - coding silent
c.1496G>A; p.G499E; 11:119134440-119134440	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.907C>T; p.L303L; 11:119132895-119132895	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1496G>A; p.G499E; 11:119134440-119134440	large_intestine; colon	carcinoma	Substitution - Missense
c.676C>T; p.Q226*; 11:119131982-119131982	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.770G>A; p.C257Y; 11:119132676-119132676	skin	malignant_melanoma	Substitution - Missense
c.770G>A; p.C257Y; 11:119132676-119132676	skin	malignant_melanoma	Substitution - Missense
c.949G>T; p.E317*; 11:119132937-119132937	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1093C>T; p.R365C; 11:119133173-119133173	skin	malignant_melanoma	Substitution - Missense
c.1345G>C; p.E449Q; 11:119134289-119134289	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.339C>T; p.I113I; 11:119130882-119130882	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.444G>T; p.R148R; 11:119131567-119131567	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.403C>A; p.H135N; 11:119130946-119130946	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.251G>T; p.R84L; 11:119130794-119130794	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1098G>A; p.K366K; 11:119133178-119133178	skin	malignant_melanoma	Substitution - coding silent
c.1513C>T; p.L505F; 11:119134457-119134457	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.194C>G; p.S65C; 11:119130737-119130737	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1168C>T; p.R390W; 11:119134112-119134112	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.721G>C; p.E241Q; 11:119132540-119132540	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1168C>T; p.R390W; 11:119134112-119134112	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.771C>T; p.C257C; 11:119132677-119132677	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.981C>T; p.C327C; 11:119132969-119132969	breast	carcinoma	Substitution - coding silent
c.4C>T; p.P2S; 11:119126948-119126948	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.363C>T; p.V121V; 11:119130906-119130906	pancreas	carcinoma	Substitution - coding silent
c.69C>T; p.S23S; 11:119127013-119127013	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.963C>A; p.F321L; 11:119132951-119132951	liver	carcinoma	Substitution - Missense
c.846G>T; p.R282R; 11:119132752-119132752	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1416_1417CC>TT; p.Q473*; 11:119134360-119134361	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1307C>T; p.P436L; 11:119134251-119134251	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1066C>A; p.R356R; 11:119133146-119133146	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.829C>T; p.R277C; 11:119132735-119132735	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.829C>T; p.R277C; 11:119132735-119132735	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.626C>T; p.A209V; 11:119131932-119131932	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.963C>T; p.F321F; 11:119132951-119132951	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.265C>A; p.H89N; 11:119130808-119130808	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1191G>C; p.E397D; 11:119134135-119134135	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1406A>T; p.Q469L; 11:119134350-119134350	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.550A>G; p.S184G; 11:119131856-119131856	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1140-1G>T; p.?; 11:119134083-119134083	large_intestine; colon	carcinoma	Unknown
c.660C>G; p.R220R; 11:119131966-119131966	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.854A>C; p.K285T; 11:119132760-119132760	skin; arm	malignant_melanoma	Substitution - Missense
c.427C>T; p.P143S; 11:119131550-119131550	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.559C>T; p.R187*; 11:119131865-119131865	skin	malignant_melanoma	Substitution - Nonsense
c.985A>G; p.I329V; 11:119132973-119132973	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.724C>T; p.R242W; 11:119132543-119132543	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.144_149delGGAGGA; p.E55_E56delEE; 11:119127088-119127093	large_intestine	carcinoma; adenocarcinoma	Deletion - In frame
c.420C>T; p.F140F; 11:119131543-119131543	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.655C>T; p.R219C; 11:119131961-119131961	skin	malignant_melanoma	Substitution - Missense
c.1015G>T; p.G339*; 11:119133095-119133095	pancreas	NS	Substitution - Nonsense
c.983C>A; p.S328Y; 11:119132971-119132971	pancreas	carcinoma	Substitution - Missense
c.416C>T; p.S139F; 11:119131539-119131539	skin	malignant_melanoma	Substitution - Missense
c.416C>T; p.S139F; 11:119131539-119131539	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.980G>T; p.C327F; 11:119132968-119132968	breast	carcinoma	Substitution - Missense
c.795G>A; p.P265P; 11:119132701-119132701	breast	carcinoma	Substitution - coding silent
c.1118C>T; p.P373L; 11:119133198-119133198	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1001G>A; p.R334H; 11:119132989-119132989	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.955T>C; p.C319R; 11:119132943-119132943	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.562G>T; p.E188*; 11:119131868-119131868	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense

COSMIC somatic mutation [Top]