Entrez Gene

Basic Information
Gene ID	250
Name	ALPP
Synonymous	alkaline phosphatase, placental;ALPP;alkaline phosphatase, placental
Definition	alkaline phosphatase Regan isozyme\|alkaline phosphatase, placental type\|alkaline phosphomonoesterase\|glycerophosphatase\|placental alkaline phosphatase 1
Position	2q37
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.537C>T; p.A179A; 2:232379816-232379816	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.10C>T; p.P4S; 2:232378812-232378812	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.10C>T; p.P4S; 2:232378812-232378812	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1590G>A; p.E530E; 2:232381777-232381777	skin	malignant_melanoma	Substitution - coding silent
c.804T>C; p.Y268Y; 2:232380431-232380431	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.814C>T; p.R272C; 2:232380441-232380441	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.814C>T; p.R272C; 2:232380441-232380441	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.1303G>A; p.E435K; 2:232381361-232381361	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1489G>A; p.D497N; 2:232381676-232381676	skin	malignant_melanoma	Substitution - Missense
c.782C>T; p.A261V; 2:232380310-232380310	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.290C>T; p.P97L; 2:232379296-232379296	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.782C>T; p.A261V; 2:232380310-232380310	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.440G>A; p.R147H; 2:232379643-232379643	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1350C>G; p.D450E; 2:232381537-232381537	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.586G>A; p.V196M; 2:232379865-232379865	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.191A>C; p.D64A; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.191A>C; p.D64A; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.191A>C; p.D64A; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.191A>C; p.D64A; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.191A>C; p.D64A; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1351G>A; p.E451K; 2:232381538-232381538	skin	malignant_melanoma	Substitution - Missense
c.191A>C; p.D64A; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.191A>C; p.D64A; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.191A>C; p.D64A; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.191A>C; p.D64A; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.191A>C; p.D64A; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.191A>C; p.D64A; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.826A>C; p.M276L; 2:232380453-232380453	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.369C>T; p.C123C; 2:232379572-232379572	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1389G>A; p.A463A; 2:232381576-232381576	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.564C>T; p.R188R; 2:232379843-232379843	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1368C>T; p.G456G; 2:232381555-232381555	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.43C>A; p.L15M; 2:232378845-232378845	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1245C>T; p.Y415Y; 2:232381303-232381303	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.77-7T>C; p.?; 2:232378964-232378964	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.1245C>T; p.Y415Y; 2:232381303-232381303	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1220G>A; p.R407K; 2:232381278-232381278	skin	malignant_melanoma	Substitution - Missense
c.265A>C; p.I89L; 2:232379271-232379271	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.850G>T; p.V284L; 2:232380477-232380477	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.861C>A; p.L287L; 2:232380488-232380488	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.861C>A; p.L287L; 2:232380488-232380488	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.1269C>T; p.L423L; 2:232381327-232381327	ovary	other; neoplasm	Substitution - coding silent
c.209C>T; p.T70M; 2:232379215-232379215	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.209C>T; p.T70M; 2:232379215-232379215	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.747G>C; p.R249S; 2:232380275-232380275	breast	carcinoma	Substitution - Missense
c.329A>T; p.H110L; 2:232379532-232379532	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1482C>T; p.T494T; 2:232381669-232381669	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.291A>G; p.P97P; 2:232379297-232379297	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.737G>A; p.G246D; 2:232380265-232380265	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1275C>T; p.D425D; 2:232381333-232381333	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.609delG; p.C205fs*16; 2:232379888-232379888	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1276G>T; p.G426C; 2:232381334-232381334	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.265A>T; p.I89L; 2:232379271-232379271	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.265A>T; p.I89L; 2:232379271-232379271	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.865+5T>G; p.?; 2:232380497-232380497	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1530G>A; p.P510P; 2:232381717-232381717	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1589A>G; p.E530G; 2:232381776-232381776	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1273G>T; p.D425Y; 2:232381331-232381331	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.498A>C; p.G166G; 2:232379777-232379777	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.664C>T; p.L222L; 2:232380192-232380192	skin	malignant_melanoma	Substitution - coding silent
c.547G>A; p.A183T; 2:232379826-232379826	central_nervous_system; brain	glioma; astrocytoma_Grade_II	Substitution - Missense
c.496G>A; p.G166R; 2:232379775-232379775	skin	malignant_melanoma	Substitution - Missense
c.1401G>A; p.Q467Q; 2:232381588-232381588	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.844C>A; p.P282T; 2:232380471-232380471	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1006C>T; p.R336C; 2:232380845-232380845	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.76+10C>A; p.?; 2:232378888-232378888	pancreas	carcinoma	Unknown
c.619G>A; p.D207N; 2:232379898-232379898	skin	malignant_melanoma	Substitution - Missense
c.619G>A; p.D207N; 2:232379898-232379898	skin	malignant_melanoma	Substitution - Missense
c.1317C>T; p.P439P; 2:232381504-232381504	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.782C>G; p.A261G; 2:232380310-232380310	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.782C>G; p.A261G; 2:232380310-232380310	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.782C>G; p.A261G; 2:232380310-232380310	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.782C>G; p.A261G; 2:232380310-232380310	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.782C>G; p.A261G; 2:232380310-232380310	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.782C>G; p.A261G; 2:232380310-232380310	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.782C>G; p.A261G; 2:232380310-232380310	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.782C>G; p.A261G; 2:232380310-232380310	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.782C>G; p.A261G; 2:232380310-232380310	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1593G>A; p.T531T; 2:232381780-232381780	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.782C>G; p.A261G; 2:232380310-232380310	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.955C>T; p.R319C; 2:232380712-232380712	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.782C>G; p.A261G; 2:232380310-232380310	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.782C>G; p.A261G; 2:232380310-232380310	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.531G>A; p.S177S; 2:232379810-232379810	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.782C>G; p.A261G; 2:232380310-232380310	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1297G>A; p.E433K; 2:232381355-232381355	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.82G>T; p.E28*; 2:232378976-232378976	ovary	other; neoplasm	Substitution - Nonsense
c.356C>T; p.T119M; 2:232379559-232379559	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1251C>T; p.N417N; 2:232381309-232381309	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1212C>T; p.A404A; 2:232381270-232381270	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1278C>T; p.G426G; 2:232381336-232381336	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1391G>A; p.R464H; 2:232381578-232381578	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.592G>T; p.A198S; 2:232379871-232379871	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.198G>A; p.M66I; 2:232379204-232379204	skin	malignant_melanoma	Substitution - Missense
c.191A>G; p.D64G; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.191A>G; p.D64G; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.191A>G; p.D64G; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1601C>T; p.A534V; 2:232381788-232381788	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.548C>T; p.A183V; 2:232379827-232379827	skin	malignant_melanoma	Substitution - Missense
c.604C>T; p.Q202*; 2:232379883-232379883	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.763C>T; p.L255L; 2:232380291-232380291	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1167delC; p.L391fs*90; 2:232381006-232381006	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.951C>T; p.A317A; 2:232380708-232380708	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.118G>A; p.E40K; 2:232379012-232379012	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.612G>T; p.G204G; 2:232379891-232379891	breast	carcinoma	Substitution - coding silent
c.1535G>C; p.R512P; 2:232381722-232381722	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.740G>T; p.G247V; 2:232380268-232380268	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1348G>T; p.D450Y; 2:232381535-232381535	oesophagus	carcinoma	Substitution - Missense
c.109G>C; p.E37Q; 2:232379003-232379003	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.109G>C; p.E37Q; 2:232379003-232379003	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.16_17insTGC; p.L13_G14insL; 2:232378818-232378819	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - In frame
c.194-1_194GG>AA; p.?; 2:232379199-232379200	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.19C>G; p.L7V; 2:232378821-232378821	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1245C>A; p.Y415*; 2:232381303-232381303	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.74C>G; p.P25R; 2:232378876-232378876	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.675C>T; p.G225G; 2:232380203-232380203	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.923C>T; p.P308L; 2:232380680-232380680	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1546C>T; p.P516S; 2:232381733-232381733	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.978C>T; p.R326R; 2:232380735-232380735	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.845C>G; p.P282R; 2:232380472-232380472	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.109G>A; p.E37K; 2:232379003-232379003	breast	carcinoma	Substitution - Missense
c.448G>A; p.E150K; 2:232379651-232379651	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.106C>T; p.R36C; 2:232379000-232379000	central_nervous_system; brain	glioma	Substitution - Missense
c.74C>T; p.P25L; 2:232378876-232378876	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.133G>A; p.A45T; 2:232379027-232379027	pancreas	carcinoma	Substitution - Missense
c.887T>G; p.M296R; 2:232380644-232380644	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1287G>A; p.P429P; 2:232381345-232381345	skin	malignant_melanoma	Substitution - coding silent
c.657+1G>A; p.?; 2:232379937-232379937	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.815G>A; p.R272H; 2:232380442-232380442	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.865+8C>T; p.?; 2:232380500-232380500	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.435G>A; p.T145T; 2:232379638-232379638	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1352A>G; p.E451G; 2:232381539-232381539	breast	carcinoma	Substitution - Missense
c.1352A>G; p.E451G; 2:232381539-232381539	thyroid	other; neoplasm	Substitution - Missense
c.1352A>G; p.E451G; 2:232381539-232381539	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1352A>G; p.E451G; 2:232381539-232381539	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1278C>A; p.G426G; 2:232381336-232381336	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1352A>G; p.E451G; 2:232381539-232381539	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Langerhans_cell_histiocytosis	Substitution - Missense
c.1352A>G; p.E451G; 2:232381539-232381539	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.751G>T; p.D251Y; 2:232380279-232380279	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.692G>C; p.R231P; 2:232380220-232380220	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.692G>C; p.R231P; 2:232380220-232380220	thyroid	other; neoplasm	Substitution - Missense
c.692G>C; p.R231P; 2:232380220-232380220	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.692G>C; p.R231P; 2:232380220-232380220	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.531G>T; p.S177S; 2:232379810-232379810	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.327A>G; p.K109K; 2:232379530-232379530	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.592G>A; p.A198T; 2:232379871-232379871	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1337C>T; p.A446V; 2:232381524-232381524	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1426G>C; p.E476Q; 2:232381613-232381613	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.787C>T; p.R263C; 2:232380315-232380315	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.539G>A; p.G180D; 2:232379818-232379818	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.787C>T; p.R263C; 2:232380315-232380315	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.787C>T; p.R263C; 2:232380315-232380315	central_nervous_system; brain	glioma	Substitution - Missense
c.1462G>T; p.A488S; 2:232381649-232381649	skin	malignant_melanoma	Substitution - Missense
c.273G>A; p.L91L; 2:232379279-232379279	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1386C>T; p.F462F; 2:232381573-232381573	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.282C>G; p.D94E; 2:232379288-232379288	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.415C>T; p.R139C; 2:232379618-232379618	central_nervous_system; brain	glioma	Substitution - Missense
c.415C>T; p.R139C; 2:232379618-232379618	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.17_19delTGC; p.L13delL; 2:232378819-232378821	stomach	carcinoma; diffuse_adenocarcinoma	Deletion - In frame
c.17_19delTGC; p.L13delL; 2:232378819-232378821	lung	carcinoma; adenocarcinoma	Deletion - In frame
c.17_19delTGC; p.L13delL; 2:232378819-232378821	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.17_19delTGC; p.L13delL; 2:232378819-232378821	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - In frame
c.17_19delTGC; p.L13delL; 2:232378819-232378821	breast	carcinoma	Deletion - In frame
c.17_19delTGC; p.L13delL; 2:232378819-232378821	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.788G>A; p.R263H; 2:232380316-232380316	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.788G>A; p.R263H; 2:232380316-232380316	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.788G>A; p.R263H; 2:232380316-232380316	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.629C>T; p.T210M; 2:232379908-232379908	breast	carcinoma	Substitution - Missense
c.629C>T; p.T210M; 2:232379908-232379908	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.788G>A; p.R263H; 2:232380316-232380316	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.191A>T; p.D64V; 2:232379085-232379085	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.215C>T; p.T72I; 2:232379221-232379221	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.794G>A; p.G265D; 2:232380421-232380421	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.639C>G; p.I213M; 2:232379918-232379918	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.825C>G; p.L275L; 2:232380452-232380452	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1502C>G; p.P501R; 2:232381689-232381689	NS	malignant_melanoma	Substitution - Missense
c.838C>T; p.L280L; 2:232380465-232380465	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.838C>T; p.L280L; 2:232380465-232380465	skin	malignant_melanoma	Substitution - coding silent
c.294T>C; p.Y98Y; 2:232379300-232379300	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.759G>A; p.K253K; 2:232380287-232380287	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.772G>A; p.E258K; 2:232380300-232380300	skin	malignant_melanoma	Substitution - Missense

COSMIC somatic mutation [Top]