Entrez Gene

Basic Information
Gene ID	23765
Name	IL17RA
Synonymous	interleukin 17 receptor A;IL17RA;interleukin 17 receptor A
Definition	IL-17 receptor A\|interleukin-17 receptor A
Position	22q11.1
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1173C>T; p.Y391Y; 22:17108392-17108392	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1423G>T; p.V475L; 22:17108642-17108642	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.631A>T; p.T211S; 22:17102171-17102171	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2239C>G; p.H747D; 22:17109458-17109458	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2239C>G; p.H747D; 22:17109458-17109458	large_intestine; colon	carcinoma	Substitution - Missense
c.2239C>G; p.H747D; 22:17109458-17109458	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.551-9G>T; p.?; 22:17101987-17101987	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1637G>A; p.R546H; 22:17108856-17108856	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2209C>G; p.P737A; 22:17109428-17109428	pancreas	carcinoid-endocrine_tumour	Substitution - Missense
c.1124T>C; p.L375P; 22:17108343-17108343	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.621C>T; p.I207I; 22:17102161-17102161	skin	malignant_melanoma	Substitution - coding silent
c.1862C>T; p.A621V; 22:17109081-17109081	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.376T>A; p.C126S; 22:17098840-17098840	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.632C>T; p.T211I; 22:17102172-17102172	breast	carcinoma	Substitution - Missense
c.2442G>T; p.E814D; 22:17109661-17109661	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2588G>T; p.G863V; 22:17109807-17109807	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1919G>T; p.G640V; 22:17109138-17109138	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.516C>T; p.D172D; 22:17100447-17100447	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.516C>T; p.D172D; 22:17100447-17100447	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1588G>A; p.E530K; 22:17108807-17108807	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1046-1G>A; p.?; 22:17107726-17107726	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Unknown
c.139-2A>T; p.?; 22:17097060-17097060	stomach	carcinoma; adenocarcinoma	Unknown
c.2458G>T; p.D820Y; 22:17109677-17109677	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1423G>A; p.V475M; 22:17108642-17108642	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.850C>T; p.Q284*; 22:17104729-17104729	liver	carcinoma	Substitution - Nonsense
c.1458C>T; p.I486I; 22:17108677-17108677	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1458C>T; p.I486I; 22:17108677-17108677	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1458C>T; p.I486I; 22:17108677-17108677	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1707C>T; p.A569A; 22:17108926-17108926	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.511G>T; p.G171W; 22:17100442-17100442	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1262C>T; p.S421L; 22:17108481-17108481	skin	malignant_melanoma	Substitution - Missense
c.1645C>T; p.R549C; 22:17108864-17108864	liver	carcinoma	Substitution - Missense
c.1645C>T; p.R549C; 22:17108864-17108864	liver	carcinoma	Substitution - Missense
c.2295delG; p.G767fs*70; 22:17109514-17109514	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.762+2T>C; p.?; 22:17102304-17102304	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.367G>A; p.E123K; 22:17098831-17098831	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2410delC; p.E806fs*31; 22:17109629-17109629	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1489G>T; p.G497C; 22:17108708-17108708	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2410delC; p.E806fs*31; 22:17109629-17109629	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2111C>T; p.P704L; 22:17109330-17109330	pancreas	carcinoma	Substitution - Missense
c.959G>T; p.W320L; 22:17105868-17105868	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.581C>T; p.T194M; 22:17102026-17102026	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.959G>T; p.W320L; 22:17105868-17105868	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2250C>A; p.G750G; 22:17109469-17109469	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2269G>A; p.E757K; 22:17109488-17109488	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1349G>A; p.G450D; 22:17108568-17108568	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.196C>T; p.R66*; 22:17097829-17097829	skin	malignant_melanoma	Substitution - Nonsense
c.196C>T; p.R66*; 22:17097829-17097829	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.196C>T; p.R66*; 22:17097829-17097829	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1167C>T; p.P389P; 22:17108386-17108386	skin; arm	malignant_melanoma	Substitution - coding silent
c.535A>C; p.N179H; 22:17100466-17100466	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2160C>T; p.P720P; 22:17109379-17109379	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1503C>G; p.V501V; 22:17108722-17108722	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.1407C>T; p.C469C; 22:17108626-17108626	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.2229C>T; p.D743D; 22:17109448-17109448	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2154C>T; p.F718F; 22:17109373-17109373	skin	malignant_melanoma	Substitution - coding silent
c.811C>T; p.R271C; 22:17103542-17103542	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2218C>T; p.L740F; 22:17109437-17109437	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.551-1G>C; p.?; 22:17101995-17101995	stomach	carcinoma; intestinal_adenocarcinoma	Unknown
c.1381C>T; p.R461W; 22:17108600-17108600	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.652C>T; p.R218C; 22:17102192-17102192	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1806C>T; p.D602D; 22:17109025-17109025	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.388G>C; p.E130Q; 22:17098852-17098852	breast	carcinoma	Substitution - Missense
c.762G>C; p.A254A; 22:17102302-17102302	skin	malignant_melanoma	Substitution - coding silent
c.2100C>T; p.G700G; 22:17109319-17109319	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1143G>C; p.W381C; 22:17108362-17108362	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.73G>T; p.V25L; 22:17085164-17085164	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.598+1G>A; p.?; 22:17102044-17102044	ovary	carcinoma; serous_carcinoma	Unknown
c.816C>T; p.N272N; 22:17103547-17103547	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1886C>G; p.S629C; 22:17109105-17109105	urinary_tract; bladder	carcinoma	Substitution - Missense
c.728A>G; p.H243R; 22:17102268-17102268	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.895G>A; p.A299T; 22:17104774-17104774	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1674C>T; p.Y558Y; 22:17108893-17108893	skin	malignant_melanoma	Substitution - coding silent
c.218C>T; p.P73L; 22:17097851-17097851	skin	malignant_melanoma	Substitution - Missense
c.1347C>T; p.R449R; 22:17108566-17108566	skin	malignant_melanoma	Substitution - coding silent
c.382A>G; p.R128G; 22:17098846-17098846	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.942G>A; p.P314P; 22:17105601-17105601	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.1664G>T; p.G555V; 22:17108883-17108883	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2068G>A; p.A690T; 22:17109287-17109287	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2248G>A; p.G750S; 22:17109467-17109467	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.675C>T; p.N225N; 22:17102215-17102215	pancreas	carcinoma	Substitution - coding silent
c.675C>T; p.N225N; 22:17102215-17102215	pancreas	carcinoma	Substitution - coding silent
c.675C>T; p.N225N; 22:17102215-17102215	thyroid	carcinoma	Substitution - coding silent
c.675C>T; p.N225N; 22:17102215-17102215	pancreas	carcinoma	Substitution - coding silent
c.498G>T; p.K166N; 22:17100429-17100429	skin; ankle	malignant_melanoma; acral_lentiginous	Substitution - Missense
c.653G>A; p.R218H; 22:17102193-17102193	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2402delC; p.P802fs*35; 22:17109621-17109621	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.599G>A; p.G200D; 22:17102139-17102139	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2053C>T; p.P685S; 22:17109272-17109272	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1431C>T; p.D477D; 22:17108650-17108650	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1531_1532GG>AA; p.G511N; 22:17108750-17108751	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2409_2410insC; p.E806fs*>62; 22:17109628-17109629	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.554G>A; p.C185Y; 22:17101999-17101999	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2231T>C; p.V744A; 22:17109450-17109450	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1540_1541CC>TT; p.P514F; 22:17108759-17108760	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1332C>T; p.I444I; 22:17108551-17108551	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1950G>A; p.L650L; 22:17109169-17109169	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1516G>T; p.E506*; 22:17108735-17108735	lung	carcinoma; small_cell_carcinoma	Substitution - Nonsense
c.378C>T; p.C126C; 22:17098842-17098842	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.379G>A; p.V127I; 22:17098843-17098843	pancreas	carcinoma	Substitution - Missense
c.1113C>T; p.I371I; 22:17108332-17108332	skin; neck	malignant_melanoma	Substitution - coding silent
c.640G>T; p.A214S; 22:17102180-17102180	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.153G>A; p.T51T; 22:17097076-17097076	breast	carcinoma	Substitution - coding silent
c.1381_1382insG; p.A463fs*48; 22:17108600-17108601	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.522C>G; p.N174K; 22:17100453-17100453	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1120C>T; p.P374S; 22:17108339-17108339	skin	malignant_melanoma	Substitution - Missense
c.478A>G; p.T160A; 22:17100409-17100409	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.839A>G; p.Q280R; 22:17103570-17103570	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1685C>A; p.P562Q; 22:17108904-17108904	breast	carcinoma	Substitution - Missense
c.941C>A; p.P314Q; 22:17105600-17105600	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1100C>T; p.A367V; 22:17108319-17108319	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1100C>T; p.A367V; 22:17108319-17108319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1100C>T; p.A367V; 22:17108319-17108319	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1859G>A; p.R620Q; 22:17109078-17109078	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.971T>C; p.F324S; 22:17105880-17105880	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2453A>C; p.E818A; 22:17109672-17109672	skin	malignant_melanoma	Substitution - Missense
c.170G>A; p.C57Y; 22:17097803-17097803	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.285C>T; p.H95H; 22:17097918-17097918	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1000G>A; p.G334S; 22:17105909-17105909	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.20C>T; p.P7L; 22:17085111-17085111	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.154G>T; p.V52F; 22:17097077-17097077	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1188G>A; p.L396L; 22:17108407-17108407	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.479C>T; p.T160I; 22:17100410-17100410	skin	malignant_melanoma	Substitution - Missense
c.427C>T; p.R143C; 22:17100358-17100358	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.427C>T; p.R143C; 22:17100358-17100358	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.427C>T; p.R143C; 22:17100358-17100358	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.341T>A; p.L114*; 22:17098805-17098805	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1668C>A; p.D556E; 22:17108887-17108887	pancreas	carcinoma	Substitution - Missense
c.767G>C; p.R256T; 22:17103498-17103498	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.277G>A; p.V93M; 22:17097910-17097910	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1245G>T; p.L415L; 22:17108464-17108464	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2205G>A; p.A735A; 22:17109424-17109424	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1006G>A; p.V336I; 22:17105915-17105915	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.903T>A; p.V301V; 22:17104782-17104782	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.1608C>T; p.I536I; 22:17108827-17108827	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - coding silent
c.1290C>T; p.G430G; 22:17108509-17108509	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1846G>A; p.G616S; 22:17109065-17109065	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1708G>A; p.A570T; 22:17108927-17108927	central_nervous_system; brain	glioma	Substitution - Missense
c.2549A>G; p.K850R; 22:17109768-17109768	kidney	other; neoplasm	Substitution - Missense
c.2472G>A; p.P824P; 22:17109691-17109691	liver	carcinoma	Substitution - coding silent
c.2241C>A; p.H747Q; 22:17109460-17109460	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.641C>T; p.A214V; 22:17102181-17102181	skin	malignant_melanoma	Substitution - Missense
c.2071G>A; p.A691T; 22:17109290-17109290	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2071G>A; p.A691T; 22:17109290-17109290	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1159G>A; p.D387N; 22:17108378-17108378	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1736T>G; p.V579G; 22:17108955-17108955	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2313C>T; p.P771P; 22:17109532-17109532	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]