Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

2342

Name

FNTB

Synonymous

farnesyltransferase, CAAX box, beta;FNTB;farnesyltransferase, CAAX box, beta

Definition

CAAX farnesyltransferase subunit beta|FTase-beta|protein farnesyltransferase subunit beta|ras proteins prenyltransferase subunit beta

Position

14q23.3

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.630A>G; p.V210V; 14:65032634-65032634

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.414T>G; p.G138G; 14:65027492-65027492

 breastcarcinomaSubstitution - coding silent

c.774G>A; p.A258A; 14:65040871-65040871

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1041delG; p.L350fs*18; 14:65053323-65053323

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.914C>T; p.A305V; 14:65044402-65044402

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.914C>T; p.A305V; 14:65044402-65044402

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.826T>C; p.W276R; 14:65044314-65044314

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.848G>A; p.R283Q; 14:65044336-65044336

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.848G>A; p.R283Q; 14:65044336-65044336

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1273G>C; p.E425Q; 14:65061271-65061271

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.766C>T; p.L256L; 14:65040863-65040863

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.388C>T; p.L130L; 14:65027466-65027466

 skinmalignant_melanomaSubstitution - coding silent

c.373G>C; p.D125H; 14:65015715-65015715

 breastcarcinomaSubstitution - Missense

c.912_916delGGCGG; p.G306fs*13; 14:65044400-65044404

 stomachcarcinoma; intestinal_adenocarcinomaDeletion - Frameshift

c.752A>G; p.Y251C; 14:65040849-65040849

 livercarcinomaSubstitution - Missense

c.663C>T; p.L221L; 14:65032667-65032667

 skinmalignant_melanomaSubstitution - coding silent

c.438G>T; p.Q146H; 14:65027516-65027516

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1032G>A; p.Q344Q; 14:65053314-65053314

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1105G>A; p.G369S; 14:65054612-65054612

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1105G>A; p.G369S; 14:65054612-65054612

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.615C>A; p.Y205*; 14:65032619-65032619

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.459A>T; p.T153T; 14:65027537-65027537

 livercarcinomaSubstitution - coding silent

c.1170C>T; p.P390P; 14:65054677-65054677

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.606-10G>A; p.?; 14:65032600-65032600

 ovaryother; neoplasmUnknown

c.496G>C; p.E166Q; 14:65027574-65027574

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.496G>C; p.E166Q; 14:65027574-65027574

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.772G>A; p.A258T; 14:65040869-65040869

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.41C>G; p.S14C; 14:64986994-64986994

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.116C>A; p.S39*; 14:64987069-64987069

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1000G>A; p.A334T; 14:65053282-65053282

 upper_aerodigestive_tract; pharynxcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.749G>A; p.G250D; 14:65040846-65040846

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.838C>T; p.R280W; 14:65044326-65044326

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.949G>A; p.A317T; 14:65044437-65044437

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.556C>T; p.Q186*; 14:65027732-65027732

 urinary_tract; bladdercarcinomaSubstitution - Nonsense

c.556C>T; p.Q186*; 14:65027732-65027732

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Nonsense

c.1145T>C; p.L382S; 14:65054652-65054652

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.432C>T; p.P144P; 14:65027510-65027510

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.810G>A; p.L270L; 14:65040907-65040907

 pancreascarcinomaSubstitution - coding silent

c.1041G>A; p.A347A; 14:65053323-65053323

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1041G>A; p.A347A; 14:65053323-65053323

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1229A>T; p.Q410L; 14:65061227-65061227

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.409G>T; p.E137*; 14:65027487-65027487

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.709G>T; p.G237C; 14:65040806-65040806

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1134C>T; p.S378S; 14:65054641-65054641

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.661C>T; p.L221F; 14:65032665-65032665

 skin; neckmalignant_melanomaSubstitution - Missense

c.627C>G; p.S209S; 14:65032631-65032631

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.916G>A; p.G306R; 14:65044404-65044404

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1177G>A; p.A393T; 14:65054684-65054684

 prostatecarcinomaSubstitution - Missense

c.701A>G; p.N234S; 14:65040798-65040798

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.917G>A; p.G306E; 14:65044405-65044405

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1072C>T; p.R358C; 14:65054579-65054579

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1246C>T; p.L416L; 14:65061244-65061244

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1246C>T; p.L416L; 14:65061244-65061244

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.327C>G; p.H109Q; 14:65015669-65015669

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.174C>T; p.V58V; 14:65004278-65004278

 skinmalignant_melanomaSubstitution - coding silent

c.51C>T; p.P17P; 14:64987004-64987004

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.939C>T; p.R313R; 14:65044427-65044427

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.720C>T; p.G240G; 14:65040817-65040817

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.162G>T; p.K54N; 14:65004266-65004266

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.679G>C; p.E227Q; 14:65032683-65032683

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense