Entrez Gene

Basic Information
Gene ID	2294
Name	FOXF1
Synonymous	forkhead box F1;FOXF1;forkhead box F1
Definition	FREAC-1\|Forkhead, drosophila, homolog-like 5\|forkhead box protein F1\|forkhead-related activator 1\|forkhead-related protein FKHL5\|forkhead-related transcription factor 1
Position	16q24
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.126G>A; p.K42K; 16:86510770-86510770	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.106A>T; p.I36F; 16:86510750-86510750	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.947G>A; p.R316Q; 16:86512967-86512967	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.905-2A>G; p.?; 16:86512923-86512923	central_nervous_system; brain	glioma	Unknown
c.823C>A; p.L275M; 16:86511467-86511467	urinary_tract; bladder	carcinoma	Substitution - Missense
c.465G>A; p.S155S; 16:86511109-86511109	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.138G>A; p.L46L; 16:86510782-86510782	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.951_952GG>AT; p.E318*; 16:86512971-86512972	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.299A>G; p.D100G; 16:86510943-86510943	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.766G>A; p.G256S; 16:86511410-86511410	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.944A>C; p.D315A; 16:86512964-86512964	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.77A>G; p.Y26C; 16:86510721-86510721	skin	malignant_melanoma	Substitution - Missense
c.103G>A; p.A35T; 16:86510747-86510747	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.907_909ATC>TGT; p.I303L; 16:86512927-86512929	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.555C>G; p.S185R; 16:86511199-86511199	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.46G>A; p.A16T; 16:86510690-86510690	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.113G>A; p.S38N; 16:86510757-86510757	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.770C>T; p.A257V; 16:86511414-86511414	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.570C>T; p.H190H; 16:86511214-86511214	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.728C>T; p.A243V; 16:86511372-86511372	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.490G>A; p.E164K; 16:86511134-86511134	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.993G>T; p.M331I; 16:86513013-86513013	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1062G>T; p.M354I; 16:86513082-86513082	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.809C>T; p.P270L; 16:86511453-86511453	pancreas	carcinoma	Substitution - Missense
c.538G>A; p.G180S; 16:86511182-86511182	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.769G>A; p.A257T; 16:86511413-86511413	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.769G>A; p.A257T; 16:86511413-86511413	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.232A>G; p.N78D; 16:86510876-86510876	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.386T>C; p.M129T; 16:86511030-86511030	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.457G>A; p.G153S; 16:86511101-86511101	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.303G>C; p.P101P; 16:86510947-86510947	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.651G>A; p.S217S; 16:86511295-86511295	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - coding silent
c.524C>T; p.P175L; 16:86511168-86511168	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.930G>T; p.S310S; 16:86512950-86512950	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.350G>A; p.R117H; 16:86510994-86510994	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.350G>A; p.R117H; 16:86510994-86510994	stomach	adenocarcinoma	Substitution - Missense
c.1057G>A; p.V353M; 16:86513077-86513077	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.409G>A; p.G137S; 16:86511053-86511053	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.240C>T; p.C80C; 16:86510884-86510884	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.401A>G; p.N134S; 16:86511045-86511045	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.401A>G; p.N134S; 16:86511045-86511045	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.558C>T; p.H186H; 16:86511202-86511202	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.558C>T; p.H186H; 16:86511202-86511202	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.596A>G; p.Y199C; 16:86511240-86511240	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.347C>T; p.P116L; 16:86510991-86510991	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.945C>T; p.D315D; 16:86512965-86512965	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.973G>A; p.A325T; 16:86512993-86512993	large_intestine; colon	carcinoma	Substitution - Missense
c.304G>C; p.A102P; 16:86510948-86510948	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.994C>T; p.H332Y; 16:86513014-86513014	liver	carcinoma	Substitution - Missense
c.15G>A; p.S5S; 16:86510659-86510659	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.142G>A; p.E48K; 16:86510786-86510786	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.142G>A; p.E48K; 16:86510786-86510786	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1042G>T; p.D348Y; 16:86513062-86513062	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1056C>A; p.C352*; 16:86513076-86513076	autonomic_ganglia	neuroblastoma	Substitution - Nonsense
c.498C>T; p.G166G; 16:86511142-86511142	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.216C>A; p.R72R; 16:86510860-86510860	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1042G>A; p.D348N; 16:86513062-86513062	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.430A>G; p.T144A; 16:86511074-86511074	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.528C>T; p.G176G; 16:86511172-86511172	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.528C>T; p.G176G; 16:86511172-86511172	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.837C>T; p.L279L; 16:86511481-86511481	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.837C>T; p.L279L; 16:86511481-86511481	liver	carcinoma	Substitution - coding silent
c.827C>T; p.S276F; 16:86511471-86511471	skin	malignant_melanoma	Substitution - Missense
c.507G>A; p.M169I; 16:86511151-86511151	skin	malignant_melanoma	Substitution - Missense
c.912G>A; p.P304P; 16:86512932-86512932	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.427G>A; p.D143N; 16:86511071-86511071	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.923C>T; p.S308L; 16:86512943-86512943	skin	malignant_melanoma	Substitution - Missense
c.312G>T; p.E104D; 16:86510956-86510956	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.449C>T; p.S150L; 16:86511093-86511093	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.956T>G; p.F319C; 16:86512976-86512976	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.304G>A; p.A102T; 16:86510948-86510948	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.395T>C; p.M132T; 16:86511039-86511039	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.359G>A; p.R120Q; 16:86511003-86511003	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.337C>T; p.R113W; 16:86510981-86510981	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.337C>T; p.R113W; 16:86510981-86510981	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.337C>T; p.R113W; 16:86510981-86510981	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.401A>T; p.N134I; 16:86511045-86511045	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.730G>A; p.A244T; 16:86511374-86511374	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; polycythaemia_vera	Substitution - Missense
c.846C>T; p.H282H; 16:86511490-86511490	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1063T>G; p.*355G; 16:86513083-86513083	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Nonstop extension
c.851T>G; p.L284R; 16:86511495-86511495	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.851T>G; p.L284R; 16:86511495-86511495	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.851T>G; p.L284R; 16:86511495-86511495	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.851T>G; p.L284R; 16:86511495-86511495	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.851T>G; p.L284R; 16:86511495-86511495	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.851T>G; p.L284R; 16:86511495-86511495	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.162G>C; p.Q54H; 16:86510806-86510806	urinary_tract; bladder	carcinoma	Substitution - Missense
c.108C>T; p.I36I; 16:86510752-86510752	skin	malignant_melanoma	Substitution - coding silent
c.1026G>A; p.Q342Q; 16:86513046-86513046	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.394A>G; p.M132V; 16:86511038-86511038	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.160C>A; p.Q54K; 16:86510804-86510804	lung	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]