Entrez Gene

Basic Information
Gene ID	1809
Name	DPYSL3
Synonymous	dihydropyrimidinase-like 3;DPYSL3;dihydropyrimidinase-like 3
Definition	collapsin response mediator protein 4 long\|dihydropyrimidinase-related protein 3\|unc-33-like phosphoprotein 1
Position	5q32
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1091T>C; p.V364A; 5:147400711-147400711	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.1490G>A; p.G497D; 5:147395693-147395693	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.963G>C; p.L321L; 5:147401545-147401545	skin	malignant_melanoma	Substitution - coding silent
c.341C>T; p.S114F; 5:147415846-147415846	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1266C>A; p.A422A; 5:147399097-147399097	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.621+9G>A; p.?; 5:147412599-147412599	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.893C>T; p.A298V; 5:147401615-147401615	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1545C>T; p.P515P; 5:147395638-147395638	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.893C>T; p.A298V; 5:147401615-147401615	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1299C>A; p.I433I; 5:147397828-147397828	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1018C>G; p.Q340E; 5:147400784-147400784	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.442G>A; p.V148I; 5:147415745-147415745	liver	carcinoma	Substitution - Missense
c.366A>C; p.K122N; 5:147415821-147415821	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.257T>A; p.V86E; 5:147418503-147418503	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1377G>A; p.L459L; 5:147397750-147397750	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1001G>T; p.C334F; 5:147400801-147400801	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1228G>A; p.V410I; 5:147399135-147399135	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.82G>A; p.D28N; 5:147424921-147424921	breast	carcinoma	Substitution - Missense
c.1081C>A; p.R361R; 5:147400721-147400721	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1087T>A; p.S363T; 5:147400715-147400715	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.1668C>T; p.I556I; 5:147394080-147394080	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.541-1G>A; p.?; 5:147412689-147412689	stomach	carcinoma; adenocarcinoma	Unknown
c.1487G>T; p.R496M; 5:147395696-147395696	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1698C>G; p.I566M; 5:147394050-147394050	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.852C>A; p.G284G; 5:147401656-147401656	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.852C>A; p.G284G; 5:147401656-147401656	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.942G>A; p.P314P; 5:147401566-147401566	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - coding silent
c.673C>A; p.L225M; 5:147408745-147408745	ovary	other; neoplasm	Substitution - Missense
c.211G>A; p.D71N; 5:147418549-147418549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.211G>A; p.D71N; 5:147418549-147418549	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1431T>G; p.Y477*; 5:147397696-147397696	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Nonsense
c.726T>C; p.I242I; 5:147405695-147405695	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.557C>T; p.T186I; 5:147412672-147412672	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.149T>G; p.I50S; 5:147418611-147418611	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1473G>A; p.L491L; 5:147395710-147395710	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1473G>A; p.L491L; 5:147395710-147395710	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.631C>T; p.R211C; 5:147408787-147408787	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.1366G>A; p.D456N; 5:147397761-147397761	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.682C>A; p.P228T; 5:147408736-147408736	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.590T>C; p.V197A; 5:147412639-147412639	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.692T>G; p.L231R; 5:147405729-147405729	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1284G>A; p.A428A; 5:147397843-147397843	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.657C>T; p.G219G; 5:147408761-147408761	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.810A>T; p.K270N; 5:147405611-147405611	ovary	other; neoplasm	Substitution - Missense
c.1199G>T; p.R400I; 5:147399164-147399164	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1024G>A; p.A342T; 5:147400778-147400778	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1578G>A; p.P526P; 5:147395605-147395605	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1578G>A; p.P526P; 5:147395605-147395605	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.380C>T; p.A127V; 5:147415807-147415807	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1526C>A; p.T509N; 5:147395657-147395657	skin	malignant_melanoma	Substitution - Missense
c.712C>T; p.R238C; 5:147405709-147405709	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.629C>A; p.T210N; 5:147408789-147408789	ovary	other; neoplasm	Substitution - Missense
c.1605G>A; p.Q535Q; 5:147395578-147395578	skin	malignant_melanoma	Substitution - coding silent
c.262G>T; p.D88Y; 5:147418498-147418498	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.364A>C; p.K122Q; 5:147415823-147415823	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1283C>T; p.A428V; 5:147397844-147397844	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.132A>T; p.Q44H; 5:147418628-147418628	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.832C>A; p.P278T; 5:147401676-147401676	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1129G>A; p.E377K; 5:147399234-147399234	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.203G>A; p.G68E; 5:147418557-147418557	breast	carcinoma	Substitution - Missense
c.374A>T; p.E125V; 5:147415813-147415813	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.422T>C; p.I141T; 5:147415765-147415765	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.207C>T; p.G69G; 5:147418553-147418553	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.964G>T; p.A322S; 5:147401544-147401544	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1084A>C; p.M362L; 5:147400718-147400718	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1084A>C; p.M362L; 5:147400718-147400718	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1195G>A; p.G399R; 5:147399168-147399168	skin	malignant_melanoma	Substitution - Missense
c.1081C>T; p.R361W; 5:147400721-147400721	breast	carcinoma	Substitution - Missense
c.1167C>A; p.A389A; 5:147399196-147399196	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1032G>A; p.G344G; 5:147400770-147400770	skin	malignant_melanoma	Substitution - coding silent
c.203G>C; p.G68A; 5:147418557-147418557	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.694G>A; p.E232K; 5:147405727-147405727	breast	carcinoma	Substitution - Missense
c.203G>C; p.G68A; 5:147418557-147418557	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1642G>T; p.G548W; 5:147394106-147394106	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1674G>A; p.A558A; 5:147394074-147394074	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1674G>A; p.A558A; 5:147394074-147394074	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.898G>A; p.A300T; 5:147401610-147401610	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.981G>A; p.Q327Q; 5:147400821-147400821	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.763G>T; p.V255F; 5:147405658-147405658	pancreas	carcinoma	Substitution - Missense
c.128+2T>C; p.?; 5:147424873-147424873	liver	carcinoma	Unknown
c.1498G>T; p.D500Y; 5:147395685-147395685	liver	carcinoma	Substitution - Missense
c.391A>G; p.S131G; 5:147415796-147415796	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1311G>A; p.M437I; 5:147397816-147397816	oesophagus	carcinoma	Substitution - Missense
c.161G>A; p.G54E; 5:147418599-147418599	skin	malignant_melanoma	Substitution - Missense
c.1498G>T; p.D500Y; 5:147395685-147395685	liver	carcinoma	Substitution - Missense
c.128+2T>C; p.?; 5:147424873-147424873	liver	carcinoma	Unknown
c.523C>G; p.Q175E; 5:147413613-147413613	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.463C>T; p.L155F; 5:147415724-147415724	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1A>G; p.M1V; 5:147453587-147453587	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1000T>C; p.C334R; 5:147400802-147400802	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.514G>A; p.D172N; 5:147413622-147413622	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1390G>A; p.G464R; 5:147397737-147397737	skin	malignant_melanoma	Substitution - Missense
c.304A>G; p.T102A; 5:147418456-147418456	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.614T>C; p.I205T; 5:147412615-147412615	urinary_tract; bladder	carcinoma	Substitution - Missense
c.614T>C; p.I205T; 5:147412615-147412615	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1020G>A; p.Q340Q; 5:147400782-147400782	breast	carcinoma	Substitution - coding silent
c.808A>G; p.K270E; 5:147405613-147405613	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.206G>T; p.G69V; 5:147418554-147418554	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1413C>A; p.C471*; 5:147397714-147397714	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.184G>T; p.G62W; 5:147418576-147418576	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1385C>G; p.T462S; 5:147397742-147397742	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1262C>T; p.S421F; 5:147399101-147399101	skin	malignant_melanoma	Substitution - Missense
c.1080G>T; p.E360D; 5:147400722-147400722	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1673C>T; p.A558V; 5:147394075-147394075	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.468C>G; p.I156M; 5:147415719-147415719	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1303G>A; p.E435K; 5:147397824-147397824	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.355G>A; p.A119T; 5:147415832-147415832	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1674G>T; p.A558A; 5:147394074-147394074	prostate	carcinoma	Substitution - coding silent
c.1240C>T; p.P414S; 5:147399123-147399123	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.516T>A; p.D172E; 5:147413620-147413620	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1400G>A; p.R467H; 5:147397727-147397727	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.628A>G; p.T210A; 5:147408790-147408790	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1092C>T; p.V364V; 5:147400710-147400710	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1371C>A; p.G457G; 5:147397756-147397756	breast	carcinoma	Substitution - coding silent
c.727G>T; p.A243S; 5:147405694-147405694	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.727G>T; p.A243S; 5:147405694-147405694	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.380C>A; p.A127D; 5:147415807-147415807	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.373G>T; p.E125*; 5:147415814-147415814	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1446T>G; p.I482M; 5:147397681-147397681	ovary	other; neoplasm	Substitution - Missense
c.642A>G; p.E214E; 5:147408776-147408776	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.894G>A; p.A298A; 5:147401614-147401614	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.969C>T; p.S323S; 5:147400833-147400833	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1453C>T; p.R485W; 5:147397674-147397674	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1692T>C; p.S564S; 5:147394056-147394056	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.690+1G>A; p.?; 5:147408727-147408727	stomach	carcinoma; adenocarcinoma	Unknown
c.1404C>T; p.F468F; 5:147397723-147397723	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.949A>T; p.I317F; 5:147401559-147401559	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1227C>T; p.L409L; 5:147399136-147399136	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1457G>A; p.R486K; 5:147397670-147397670	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1302T>A; p.F434L; 5:147397825-147397825	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1302T>A; p.F434L; 5:147397825-147397825	urinary_tract; bladder	carcinoma	Substitution - Missense
c.674T>A; p.L225Q; 5:147408744-147408744	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.750C>T; p.L250L; 5:147405671-147405671	skin	malignant_melanoma	Substitution - coding silent
c.812G>A; p.G271E; 5:147401696-147401696	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1076A>T; p.E359V; 5:147400726-147400726	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.441C>T; p.S147S; 5:147415746-147415746	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]