Entrez Gene

Basic Information
Gene ID	1800
Name	DPEP1
Synonymous	dipeptidase 1 (renal);DPEP1;dipeptidase 1 (renal)
Definition	dehydropeptidase-I\|dipeptidase 1\|hRDP\|microsomal dipeptidase\|renal dipeptidase
Position	16q24.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.825_827delCAA; p.N276delN; 16:89637524-89637526	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.460C>T; p.R154W; 16:89636622-89636622	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.99T>C; p.I33I; 16:89630509-89630509	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.614G>A; p.R205H; 16:89637226-89637226	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.614G>A; p.R205H; 16:89637226-89637226	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.435C>T; p.S145S; 16:89636597-89636597	skin	malignant_melanoma	Substitution - coding silent
c.348C>T; p.F116F; 16:89636374-89636374	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.561C>T; p.P187P; 16:89636905-89636905	skin	malignant_melanoma	Substitution - coding silent
c.742G>A; p.V248M; 16:89637354-89637354	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.676C>T; p.L226L; 16:89637288-89637288	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.255G>A; p.T85T; 16:89636281-89636281	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.937G>C; p.E313Q; 16:89637843-89637843	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.9C>T; p.S3S; 16:89630419-89630419	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.665C>T; p.A222V; 16:89637277-89637277	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.842C>T; p.S281F; 16:89637541-89637541	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.842C>T; p.S281F; 16:89637541-89637541	skin	malignant_melanoma	Substitution - Missense
c.42C>A; p.C14*; 16:89630452-89630452	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Nonsense
c.6G>A; p.W2*; 16:89630416-89630416	skin	malignant_melanoma	Substitution - Nonsense
c.417C>T; p.G139G; 16:89636579-89636579	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2T>C; p.M1T; 16:89630412-89630412	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.807_809delCAA; p.N270delN; 16:89637506-89637508	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Deletion - In frame
c.329G>A; p.R110Q; 16:89636355-89636355	pancreas	carcinoma	Substitution - Missense
c.665C>A; p.A222D; 16:89637277-89637277	oesophagus	carcinoma	Substitution - Missense
c.1180T>G; p.W394G; 16:89638166-89638166	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.836A>G; p.N279S; 16:89637535-89637535	skin	malignant_melanoma	Substitution - Missense
c.1095G>A; p.E365E; 16:89638081-89638081	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.877G>A; p.V293M; 16:89637655-89637655	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.268C>T; p.Q90*; 16:89636294-89636294	skin	malignant_melanoma	Substitution - Nonsense
c.174G>A; p.L58L; 16:89635977-89635977	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.737G>A; p.R246H; 16:89637349-89637349	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.630C>T; p.I210I; 16:89637242-89637242	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1228C>G; p.L410V; 16:89638214-89638214	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.862G>A; p.D288N; 16:89637640-89637640	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.916G>T; p.D306Y; 16:89637694-89637694	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.933C>T; p.V311V; 16:89637839-89637839	skin	malignant_melanoma	Substitution - coding silent
c.434C>A; p.S145Y; 16:89636596-89636596	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.31G>T; p.V11L; 16:89630441-89630441	breast	carcinoma	Substitution - Missense
c.31G>T; p.V11L; 16:89630441-89630441	breast	carcinoma	Substitution - Missense
c.592C>T; p.R198C; 16:89637204-89637204	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.637G>A; p.A213T; 16:89637249-89637249	skin	malignant_melanoma	Substitution - Missense
c.726C>T; p.C242C; 16:89637338-89637338	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1020C>T; p.G340G; 16:89637926-89637926	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1220G>A; p.C407Y; 16:89638206-89638206	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1232T>C; p.L411P; 16:89638218-89638218	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1232T>C; p.L411P; 16:89638218-89638218	large_intestine; colon	carcinoma	Substitution - Missense
c.1232T>C; p.L411P; 16:89638218-89638218	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.483G>T; p.M161I; 16:89636645-89636645	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.458T>C; p.L153P; 16:89636620-89636620	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.923T>C; p.V308A; 16:89637701-89637701	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1011G>A; p.E337E; 16:89637917-89637917	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.303G>A; p.Q101Q; 16:89636329-89636329	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.335_336insC; p.E114fs*34; 16:89636361-89636362	large_intestine; rectum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.844C>T; p.Q282*; 16:89637543-89637543	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.104+3G>A; p.?; 16:89630517-89630517	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1043G>T; p.R348M; 16:89637949-89637949	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1050C>T; p.F350F; 16:89637956-89637956	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.247G>A; p.V83M; 16:89636273-89636273	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.556G>A; p.E186K; 16:89636900-89636900	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.833C>G; p.A278G; 16:89637532-89637532	skin	malignant_melanoma	Substitution - Missense
c.1021G>A; p.A341T; 16:89637927-89637927	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.621G>A; p.G207G; 16:89637233-89637233	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.388C>T; p.R130W; 16:89636550-89636550	breast	carcinoma	Substitution - Missense
c.388C>T; p.R130W; 16:89636550-89636550	breast	carcinoma	Substitution - Missense
c.232G>T; p.G78C; 16:89636035-89636035	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.63C>T; p.D21D; 16:89630473-89630473	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1039C>G; p.L347V; 16:89637945-89637945	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.389G>T; p.R130L; 16:89636551-89636551	urinary_tract; bladder	carcinoma	Substitution - Missense
c.183G>C; p.L61F; 16:89635986-89635986	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.640C>T; p.H214Y; 16:89637252-89637252	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.286C>T; p.R96W; 16:89636312-89636312	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.992G>A; p.R331K; 16:89637898-89637898	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.992G>A; p.R331K; 16:89637898-89637898	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1051G>C; p.E351Q; 16:89637957-89637957	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.895G>A; p.V299M; 16:89637673-89637673	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.159C>G; p.D53E; 16:89635962-89635962	pancreas	carcinoma	Substitution - Missense
c.456C>T; p.V152V; 16:89636618-89636618	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.81G>A; p.M27I; 16:89630491-89630491	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.119C>T; p.P40L; 16:89635922-89635922	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.326G>T; p.C109F; 16:89636352-89636352	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.328C>T; p.R110W; 16:89636354-89636354	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1143C>T; p.Y381Y; 16:89638129-89638129	pancreas	carcinoma	Substitution - coding silent
c.1143C>T; p.Y381Y; 16:89638129-89638129	ovary	other; neoplasm	Substitution - coding silent
c.1175G>A; p.R392H; 16:89638161-89638161	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.680C>T; p.S227F; 16:89637292-89637292	skin; mucosal	malignant_melanoma	Substitution - Missense

COSMIC somatic mutation [Top]