Entrez Gene

Basic Information
Gene ID	1573
Name	CYP2J2
Synonymous	cytochrome P450, family 2, subfamily J, polypeptide 2;CYP2J2;cytochrome P450, family 2, subfamily J, polypeptide 2
Definition	CYPIIJ2\|arachidonic acid epoxygenase\|cytochrome P450 2J2\|cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2\|flavoprotein-linked monooxygenase\|microsomal monooxygenase
Position	1p31.3-p31.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.294A>G; p.K98K; 1:59916017-59916017	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.88C>A; p.L30I; 1:59926659-59926659	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.336C>T; p.P112P; 1:59915975-59915975	skin	malignant_melanoma	Substitution - coding silent
c.962G>A; p.R321Q; 1:59907827-59907827	skin	malignant_melanoma	Substitution - Missense
c.1069G>A; p.E357K; 1:59904993-59904993	skin; scalp	malignant_melanoma	Substitution - Missense
c.51T>A; p.H17Q; 1:59926696-59926696	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.903C>T; p.L301L; 1:59907886-59907886	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1324T>C; p.S442P; 1:59900971-59900971	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.987C>T; p.L329L; 1:59907802-59907802	skin	malignant_melanoma	Substitution - coding silent
c.1116G>A; p.M372I; 1:59904946-59904946	skin	malignant_melanoma	Substitution - Missense
c.516G>A; p.E172E; 1:59912169-59912169	skin	malignant_melanoma	Substitution - coding silent
c.1116G>A; p.M372I; 1:59904946-59904946	skin	malignant_melanoma	Substitution - Missense
c.961C>A; p.R321R; 1:59907828-59907828	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.397G>A; p.A133T; 1:59912288-59912288	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.332G>A; p.R111H; 1:59915979-59915979	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.599G>A; p.R200H; 1:59911693-59911693	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.696C>T; p.V232V; 1:59909949-59909949	skin	malignant_melanoma	Substitution - coding silent
c.269T>G; p.L90R; 1:59916042-59916042	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.655A>G; p.T219A; 1:59911637-59911637	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.456G>A; p.K152K; 1:59912229-59912229	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.337G>A; p.V113M; 1:59915974-59915974	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1366A>G; p.T456A; 1:59893794-59893794	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1319C>A; p.P440H; 1:59900976-59900976	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1496T>A; p.V499D; 1:59893664-59893664	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1392C>T; p.S464S; 1:59893768-59893768	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.760_761insA; p.L254fs*10; 1:59909884-59909885	lung	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.661T>C; p.L221L; 1:59911631-59911631	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.832A>G; p.I278V; 1:59909813-59909813	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.349C>T; p.R117*; 1:59915962-59915962	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Nonsense
c.419T>G; p.F140C; 1:59912266-59912266	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1369G>T; p.E457*; 1:59893791-59893791	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.141_149delCTGGCGCCT; p.W48_L50delWRL; 1:59926598-59926606	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Deletion - In frame
c.698T>C; p.F233S; 1:59909947-59909947	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.567C>T; p.S189S; 1:59911725-59911725	skin	malignant_melanoma	Substitution - coding silent
c.78C>T; p.V26V; 1:59926669-59926669	skin	malignant_melanoma	Substitution - coding silent
c.1274A>G; p.H425R; 1:59901021-59901021	liver	carcinoma	Substitution - Missense
c.935G>A; p.G312E; 1:59907854-59907854	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.417G>C; p.R139S; 1:59912268-59912268	skin	malignant_melanoma	Substitution - Missense
c.1220C>T; p.A407V; 1:59901075-59901075	soft_tissue; striated_muscle	rhabdomyosarcoma	Substitution - Missense
c.1220C>T; p.A407V; 1:59901075-59901075	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.1052C>T; p.P351L; 1:59905010-59905010	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1498C>T; p.P500S; 1:59893662-59893662	skin	malignant_melanoma	Substitution - Missense
c.304A>G; p.I102V; 1:59916007-59916007	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.495C>T; p.H165H; 1:59912190-59912190	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.331C>A; p.R111S; 1:59915980-59915980	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.758A>C; p.K253T; 1:59909887-59909887	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1469C>A; p.S490Y; 1:59893691-59893691	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1242G>A; p.E414E; 1:59901053-59901053	skin	malignant_melanoma	Substitution - coding silent
c.865A>T; p.T289S; 1:59907924-59907924	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.528G>T; p.Q176H; 1:59911764-59911764	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.528G>T; p.Q176H; 1:59911764-59911764	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.528G>T; p.Q176H; 1:59911764-59911764	large_intestine; colon	carcinoma	Substitution - Missense
c.528G>T; p.Q176H; 1:59911764-59911764	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1141C>T; p.P381S; 1:59904921-59904921	skin	malignant_melanoma	Substitution - Missense
c.134C>T; p.P45L; 1:59926613-59926613	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1200G>A; p.M400I; 1:59901095-59901095	skin	malignant_melanoma	Substitution - Missense
c.1073C>T; p.S358F; 1:59904989-59904989	skin	malignant_melanoma	Substitution - Missense
c.445G>C; p.G149R; 1:59912240-59912240	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1270G>A; p.D424N; 1:59901025-59901025	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.679T>C; p.C227R; 1:59911613-59911613	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.546C>T; p.F182F; 1:59911746-59911746	skin	malignant_melanoma	Substitution - coding silent
c.1006A>C; p.K336Q; 1:59905056-59905056	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.438G>A; p.R146R; 1:59912247-59912247	skin	malignant_melanoma	Substitution - coding silent
c.438G>A; p.R146R; 1:59912247-59912247	skin	malignant_melanoma	Substitution - coding silent
c.916C>A; p.L306M; 1:59907873-59907873	prostate	adenoma	Substitution - Missense
c.404A>G; p.K135R; 1:59912281-59912281	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1128C>T; p.I376I; 1:59904934-59904934	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.627G>T; p.Q209H; 1:59911665-59911665	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.724G>A; p.G242R; 1:59909921-59909921	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.238A>G; p.S80G; 1:59916073-59916073	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1311C>T; p.A437A; 1:59900984-59900984	skin	malignant_melanoma	Substitution - coding silent
c.1469C>T; p.S490F; 1:59893691-59893691	skin; scalp	malignant_melanoma	Substitution - Missense
c.1315A>T; p.M439L; 1:59900980-59900980	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.148C>T; p.L50L; 1:59926599-59926599	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1112G>T; p.R371I; 1:59904950-59904950	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.606G>A; p.E202E; 1:59911686-59911686	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.435A>G; p.L145L; 1:59912250-59912250	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.717C>T; p.F239F; 1:59909928-59909928	skin	malignant_melanoma	Substitution - coding silent
c.209T>A; p.L70Q; 1:59926538-59926538	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1337G>C; p.R446P; 1:59893823-59893823	NS	NS	Substitution - Missense
c.850G>T; p.E284*; 1:59909795-59909795	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.892G>A; p.E298K; 1:59907897-59907897	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1306G>A; p.E436K; 1:59900989-59900989	skin	malignant_melanoma	Substitution - Missense
c.1483C>T; p.R495C; 1:59893677-59893677	liver	carcinoma	Substitution - Missense
c.598C>T; p.R200C; 1:59911694-59911694	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.498C>A; p.L166L; 1:59912187-59912187	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.938_939CC>TT; p.T313I; 1:59907850-59907851	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]