Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

148252

Name

DIRAS1

Synonymous

DIRAS family, GTP-binding RAS-like 1;DIRAS1;DIRAS family, GTP-binding RAS-like 1

Definition

GTP-binding protein Di-Ras1|distinct subgroup of the Ras family member 1|ras-related inhibitor of cell growth|small GTP-binding tumor suppressor 1

Position

19p13.3

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.469G>A; p.V157I; 19:2717338-2717338

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.383G>A; p.R128Q; 19:2717424-2717424

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.329G>A; p.S110N; 19:2717478-2717478

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.44C>T; p.A15V; 19:2717763-2717763

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.242C>G; p.A81G; 19:2717565-2717565

 stomachadenocarcinomaSubstitution - Missense

c.70G>T; p.V24L; 19:2717737-2717737

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.406C>T; p.Q136*; 19:2717401-2717401

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.52G>A; p.V18M; 19:2717755-2717755

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.480C>T; p.L160L; 19:2717327-2717327

 skinmalignant_melanomaSubstitution - coding silent

c.352C>T; p.L118F; 19:2717455-2717455

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.28G>A; p.V10M; 19:2717779-2717779

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.134G>A; p.R45Q; 19:2717673-2717673

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.592A>G; p.M198V; 19:2717215-2717215

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.237C>T; p.G79G; 19:2717570-2717570

 ovaryother; neoplasmSubstitution - coding silent

c.509G>A; p.R170H; 19:2717298-2717298

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.278C>A; p.S93*; 19:2717529-2717529

 pancreascarcinomaSubstitution - Nonsense

c.139G>A; p.V47M; 19:2717668-2717668

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.27C>T; p.R9R; 19:2717780-2717780

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.345C>T; p.P115P; 19:2717462-2717462

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.55G>T; p.G19C; 19:2717752-2717752

 prostatecarcinomaSubstitution - Missense

c.19G>A; p.D7N; 19:2717788-2717788

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.296C>T; p.P99L; 19:2717511-2717511

 pancreascarcinomaSubstitution - Missense

c.87G>T; p.K29N; 19:2717720-2717720

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.225C>T; p.S75S; 19:2717582-2717582

 pancreascarcinomaSubstitution - coding silent

c.355G>A; p.V119M; 19:2717452-2717452

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.235G>T; p.G79C; 19:2717572-2717572

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.235G>T; p.G79C; 19:2717572-2717572

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.432C>T; p.C144C; 19:2717375-2717375

 lung; left_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.279G>A; p.S93S; 19:2717528-2717528

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.399C>T; p.R133R; 19:2717408-2717408

 breastcarcinomaSubstitution - coding silent

c.545C>T; p.S182F; 19:2717262-2717262

 skinmalignant_melanomaSubstitution - Missense

c.545C>T; p.S182F; 19:2717262-2717262

 skinmalignant_melanomaSubstitution - Missense

c.545C>T; p.S182F; 19:2717262-2717262

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.404C>T; p.A135V; 19:2717403-2717403

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.438C>T; p.F146F; 19:2717369-2717369

 skinmalignant_melanomaSubstitution - coding silent

c.41G>T; p.G14V; 19:2717766-2717766

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.356T>A; p.V119E; 19:2717451-2717451

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.190G>T; p.G64C; 19:2717617-2717617

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.547G>A; p.G183R; 19:2717260-2717260

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.382C>T; p.R128W; 19:2717425-2717425

 pancreascarcinoma; ductal_carcinomaSubstitution - Missense

c.382C>T; p.R128W; 19:2717425-2717425

 pancreascarcinomaSubstitution - Missense

c.30G>T; p.V10V; 19:2717777-2717777

 livercarcinomaSubstitution - coding silent

c.30G>T; p.V10V; 19:2717777-2717777

 livercarcinomaSubstitution - coding silent

c.206C>T; p.P69L; 19:2717601-2717601

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.5C>T; p.P2L; 19:2717802-2717802

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.71T>A; p.V24E; 19:2717736-2717736

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.136C>T; p.Q46*; 19:2717671-2717671

 skinmalignant_melanomaSubstitution - Nonsense

c.314T>C; p.V105A; 19:2717493-2717493

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.77G>A; p.R26H; 19:2717730-2717730

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.81C>T; p.F27F; 19:2717726-2717726

 skinmalignant_melanomaSubstitution - coding silent

c.449C>T; p.S150L; 19:2717358-2717358

 skinmalignant_melanomaSubstitution - Missense