| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 136 |
Name | ADORA2B |
Synonymous | adenosine A2b receptor;ADORA2B;adenosine A2b receptor |
Definition | adenosine receptor A2b |
Position | 17p12 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.215G>A; p.C72Y; 17:15945463-15945463 |
bone; extraskeletal | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Substitution - Missense |
c.928C>A; p.L310I; 17:15975271-15975271 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.531C>T; p.V177V; 17:15974874-15974874 |
bone | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Substitution - coding silent |
c.443A>G; p.D148G; 17:15974786-15974786 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.657G>A; p.M219I; 17:15975000-15975000 |
skin | malignant_melanoma | Substitution - Missense |
c.674C>T; p.T225I; 17:15975017-15975017 |
oesophagus; lower_third | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.291G>T; p.L97L; 17:15945539-15945539 |
urinary_tract; bladder | carcinoma; transitional_cell_carcinoma | Substitution - coding silent |
c.291G>T; p.L97L; 17:15945539-15945539 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.929T>C; p.L310P; 17:15975272-15975272 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.929T>C; p.L310P; 17:15975272-15975272 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.840T>C; p.H280H; 17:15975183-15975183 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.507G>A; p.V169V; 17:15974850-15974850 |
skin | malignant_melanoma | Substitution - coding silent |
c.577C>T; p.P193S; 17:15974920-15974920 |
liver | carcinoma | Substitution - Missense |
c.419C>T; p.P140L; 17:15974762-15974762 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.944T>G; p.V315G; 17:15975287-15975287 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.389G>C; p.W130S; 17:15974732-15974732 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.167_168insG; p.L58fs*17; 17:15945415-15945416 |
large_intestine; colon | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.186C>T; p.P62P; 17:15945434-15945434 |
skin | malignant_melanoma | Substitution - coding silent |
c.204C>T; p.S68S; 17:15945452-15945452 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - coding silent |
c.423C>A; p.F141L; 17:15974766-15974766 |
skin | malignant_melanoma | Substitution - Missense |
c.961C>G; p.Q321E; 17:15975304-15975304 |
breast | carcinoma | Substitution - Missense |
c.776T>C; p.F259S; 17:15975119-15975119 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.36G>T; p.A12A; 17:15945284-15945284 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.824C>T; p.A275V; 17:15975167-15975167 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.824C>T; p.A275V; 17:15975167-15975167 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.500G>A; p.C167Y; 17:15974843-15974843 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.661C>A; p.H221N; 17:15975004-15975004 |
stomach | carcinoma; intestinal_adenocarcinoma | Substitution - Missense |
c.204_205insG; p.L69fs*6; 17:15945452-15945453 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.455A>C; p.N152T; 17:15974798-15974798 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.191_192CC>TT; p.A64V; 17:15945439-15945440 |
skin | malignant_melanoma | Substitution - Missense |
c.809G>A; p.W270*; 17:15975152-15975152 |
liver | carcinoma | Substitution - Nonsense |
c.809G>A; p.W270*; 17:15975152-15975152 |
liver | carcinoma; hepatocellular_carcinoma | Substitution - Nonsense |
c.75C>T; p.N25N; 17:15945323-15945323 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.85T>C; p.C29R; 17:15945333-15945333 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.878G>A; p.R293Q; 17:15975221-15975221 |
skin | malignant_melanoma | Substitution - Missense |
c.354G>T; p.T118T; 17:15974697-15974697 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.455_457delACA; p.N153delN; 17:15974798-15974800 |
soft_tissue; striated_muscle | rhabdomyosarcoma; alveolar | Deletion - In frame |
c.982C>T; p.L328F; 17:15975325-15975325 |
skin | malignant_melanoma | Substitution - Missense |
c.746C>T; p.P249L; 17:15975089-15975089 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.338A>T; p.Y113F; 17:15974681-15974681 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.928C>T; p.L310F; 17:15975271-15975271 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.945C>A; p.V315V; 17:15975288-15975288 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |