| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 133 |
Name | ADM |
Synonymous | adrenomedullin;ADM;adrenomedullin |
Definition | preproadrenomedullin|proadrenomedullin N-20 terminal peptide |
Position | 11p15.4 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.129G>A; p.K43K; 11:10305979-10305979 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.20C>T; p.A7V; 11:10305720-10305720 |
thyroid | carcinoma | Substitution - Missense |
c.20C>T; p.A7V; 11:10305720-10305720 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.191C>T; p.A64V; 11:10306041-10306041 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.51A>G; p.L17L; 11:10305751-10305751 |
bone; fibula | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Substitution - coding silent |
c.518C>A; p.A173D; 11:10306601-10306601 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.113C>T; p.A38V; 11:10305963-10305963 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.140G>A; p.R47Q; 11:10305990-10305990 |
stomach | carcinoma; diffuse_adenocarcinoma | Substitution - Missense |
c.445C>A; p.R149R; 11:10306528-10306528 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.523_524insCC; p.S178fs*>9; 11:10306606-10306607 |
large_intestine; colon | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.438C>T; p.Y146Y; 11:10306521-10306521 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.448C>T; p.R150C; 11:10306531-10306531 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.347C>T; p.T116M; 11:10306430-10306430 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.49C>T; p.L17L; 11:10305749-10305749 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - coding silent |
c.49C>T; p.L17L; 11:10305749-10305749 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - coding silent |
c.25A>C; p.M9L; 11:10305725-10305725 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.248+1G>A; p.?; 11:10306099-10306099 |
large_intestine; colon | carcinoma; adenocarcinoma | Unknown |
c.155A>G; p.Y52C; 11:10306005-10306005 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.138_139GC>TA; p.(=); 11:10305988-10305989 |
lung | carcinoma; adenocarcinoma | Unknown |
c.23_24TG>CC; p.L8>?; 11:10305723-10305724 |
large_intestine; colon | carcinoma; adenocarcinoma | Complex |
c.23T>C; p.L8P; 11:10305723-10305723 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.23T>C; p.L8P; 11:10305723-10305723 |
urinary_tract; bladder | carcinoma; transitional_cell_carcinoma | Substitution - Missense |
c.32T>C; p.L11P; 11:10305732-10305732 |
bone | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Substitution - Missense |
c.272G>A; p.R91Q; 11:10306355-10306355 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.476C>T; p.P159L; 11:10306559-10306559 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.524delC; p.P177fs*>9; 11:10306607-10306607 |
liver | carcinoma | Deletion - Frameshift |
c.524delC; p.P177fs*>9; 11:10306607-10306607 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.524delC; p.P177fs*>9; 11:10306607-10306607 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.261C>G; p.A87A; 11:10306344-10306344 |
breast | carcinoma | Substitution - coding silent |
c.147C>A; p.S49S; 11:10305997-10305997 |
ovary | carcinoma; serous_carcinoma | Substitution - coding silent |
c.241G>A; p.E81K; 11:10306091-10306091 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.136C>A; p.L46M; 11:10305986-10305986 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.406_407insC; p.R138fs*30; 11:10306489-10306490 |
large_intestine; colon | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.122G>T; p.R41L; 11:10305972-10305972 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.338G>A; p.G113E; 11:10306421-10306421 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.523_524insC; p.S178fs*>9; 11:10306606-10306607 |
large_intestine; colon | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.87G>A; p.E29E; 11:10305787-10305787 |
kidney | other; neoplasm | Substitution - coding silent |