Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

1233

Name

CCR4

Synonymous

chemokine (C-C motif) receptor 4;CCR4;chemokine (C-C motif) receptor 4

Definition

C-C CKR-4|C-C chemokine receptor type 4|CCR-4|chemokine (C-C) receptor 4

Position

3p24

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.501C>T; p.F167F; 3:32953923-32953923

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.501C>T; p.F167F; 3:32953923-32953923

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.12G>T; p.T4T; 3:32953434-32953434

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.506_507CC>TT; p.S169F; 3:32953928-32953929

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.545G>A; p.R182H; 3:32953967-32953967

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1028C>T; p.P343L; 3:32954450-32954450

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.208C>T; p.L70F; 3:32953630-32953630

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.447G>A; p.R149R; 3:32953869-32953869

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.301G>A; p.D101N; 3:32953723-32953723

 skinmalignant_melanomaSubstitution - Missense

c.726G>T; p.K242N; 3:32954148-32954148

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.758G>T; p.G253V; 3:32954180-32954180

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.914T>G; p.F305C; 3:32954336-32954336

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.438G>T; p.L146F; 3:32953860-32953860

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.591G>A; p.T197T; 3:32954013-32954013

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.587C>T; p.T196M; 3:32954009-32954009

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.587C>T; p.T196M; 3:32954009-32954009

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.328T>C; p.C110R; 3:32953750-32953750

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.975T>G; p.L325L; 3:32954397-32954397

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.554C>T; p.T185I; 3:32953976-32953976

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.383T>A; p.V128D; 3:32953805-32953805

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1014C>T; p.Y338Y; 3:32954436-32954436

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.974T>A; p.L325H; 3:32954396-32954396

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.277C>T; p.P93S; 3:32953699-32953699

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.206G>A; p.R69Q; 3:32953628-32953628

 kidneyother; neoplasmSubstitution - Missense

c.1043C>T; p.T348M; 3:32954465-32954465

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.565A>G; p.T189A; 3:32953987-32953987

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.628G>A; p.G210R; 3:32954050-32954050

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.628G>A; p.G210R; 3:32954050-32954050

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.601C>T; p.L201F; 3:32954023-32954023

 breastcarcinomaSubstitution - Missense

c.222T>C; p.T74T; 3:32953644-32953644

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.33C>T; p.L11L; 3:32953455-32953455

 prostatecarcinomaSubstitution - coding silent

c.434C>T; p.S145F; 3:32953856-32953856

 skinmalignant_melanomaSubstitution - Missense

c.434C>T; p.S145F; 3:32953856-32953856

 skinmalignant_melanomaSubstitution - Missense

c.434C>T; p.S145F; 3:32953856-32953856

 skinmalignant_melanomaSubstitution - Missense

c.954C>T; p.L318L; 3:32954376-32954376

 skinmalignant_melanomaSubstitution - coding silent

c.531T>G; p.T177T; 3:32953953-32953953

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.901C>A; p.P301T; 3:32954323-32954323

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.532T>G; p.C178G; 3:32953954-32953954

 bone; femurEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.385A>G; p.M129V; 3:32953807-32953807

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.823G>A; p.D275N; 3:32954245-32954245

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.935G>A; p.R312H; 3:32954357-32954357

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.345G>A; p.W115*; 3:32953767-32953767

 skinmalignant_melanomaSubstitution - Nonsense

c.341C>T; p.S114F; 3:32953763-32953763

 skinmalignant_melanomaSubstitution - Missense

c.430delT; p.S145fs*2; 3:32953852-32953852

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.48C>A; p.Y16*; 3:32953470-32953470

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.70A>G; p.S24G; 3:32953492-32953492

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.453G>C; p.L151F; 3:32953875-32953875

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.273C>T; p.S91S; 3:32953695-32953695

 skinmalignant_melanomaSubstitution - coding silent

c.1027C>A; p.P343T; 3:32954449-32954449

 skinmalignant_melanomaSubstitution - Missense

c.760T>A; p.F254I; 3:32954182-32954182

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.393G>A; p.M131I; 3:32953815-32953815

 skinmalignant_melanomaSubstitution - Missense

c.365A>T; p.Y122F; 3:32953787-32953787

 livercarcinomaSubstitution - Missense

c.365A>T; p.Y122F; 3:32953787-32953787

 livercarcinomaSubstitution - Missense

c.994T>A; p.C332S; 3:32954416-32954416

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.355G>A; p.V119M; 3:32953777-32953777

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.387G>A; p.M129I; 3:32953809-32953809

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.974delT; p.F326fs*>35; 3:32954396-32954396

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.1000C>A; p.L334I; 3:32954422-32954422

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.918T>C; p.F306F; 3:32954340-32954340

 pancreascarcinomaSubstitution - coding silent

c.618C>T; p.I206I; 3:32954040-32954040

 skinmalignant_melanomaSubstitution - coding silent

c.901C>T; p.P301S; 3:32954323-32954323

 skinmalignant_melanomaSubstitution - Missense

c.299C>G; p.A100G; 3:32953721-32953721

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.104A>C; p.K35T; 3:32953526-32953526

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.776A>G; p.N259S; 3:32954198-32954198

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.776A>G; p.N259S; 3:32954198-32954198

 livercarcinomaSubstitution - Missense

c.891C>T; p.C297C; 3:32954313-32954313

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.719C>T; p.A240V; 3:32954141-32954141

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.272C>T; p.S91F; 3:32953694-32953694

 NSNSSubstitution - Missense

c.475T>A; p.L159M; 3:32953897-32953897

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.309G>A; p.W103*; 3:32953731-32953731

 prostateadenomaSubstitution - Nonsense

c.646G>T; p.G216W; 3:32954068-32954068

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.802G>A; p.V268M; 3:32954224-32954224

 skin; trunkmalignant_melanomaSubstitution - Missense

c.934C>T; p.R312C; 3:32954356-32954356

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.934C>T; p.R312C; 3:32954356-32954356

 skin; armmalignant_melanomaSubstitution - Missense

c.12G>A; p.T4T; 3:32953434-32953434

 skinmalignant_melanomaSubstitution - coding silent

c.336G>A; p.M112I; 3:32953758-32953758

 skinmalignant_melanomaSubstitution - Missense

c.336G>A; p.M112I; 3:32953758-32953758

 skinmalignant_melanomaSubstitution - Missense

c.541G>A; p.E181K; 3:32953963-32953963

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.805G>A; p.E269K; 3:32954227-32954227

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.783G>A; p.V261V; 3:32954205-32954205

 breastcarcinomaSubstitution - coding silent