Entrez Gene

Basic Information
Gene ID	1192
Name	CLIC1
Synonymous	chloride intracellular channel 1;CLIC1;chloride intracellular channel 1
Definition	RNCC protein\|chloride channel ABP\|chloride intracellular channel protein 1\|hRNCC\|nuclear chloride ion channel 27\|nuclear chloride ion channel protein\|p64CLCP\|regulatory nuclear chloride ion channel protein
Position	6p21.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.390G>A; p.E130E; 6:31732391-31732391	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.390G>A; p.E130E; 6:31732391-31732391	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.188A>G; p.Q63R; 6:31733923-31733923	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.419_420insT; p.L140fs*15; 6:31732361-31732362	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.414G>C; p.K138N; 6:31732367-31732367	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.442delC; p.L148fs*39; 6:31732339-31732339	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.442delC; p.L148fs*39; 6:31732339-31732339	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.513C>T; p.N171N; 6:31732268-31732268	liver	carcinoma	Substitution - coding silent
c.513C>T; p.N171N; 6:31732268-31732268	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.513C>T; p.N171N; 6:31732268-31732268	liver	carcinoma	Substitution - coding silent
c.513C>T; p.N171N; 6:31732268-31732268	liver	carcinoma	Substitution - coding silent
c.361T>G; p.S121A; 6:31733587-31733587	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.152G>A; p.R51Q; 6:31733959-31733959	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.190C>T; p.L64F; 6:31733921-31733921	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.123C>A; p.F41L; 6:31734180-31734180	breast	carcinoma	Substitution - Missense
c.667T>C; p.C223R; 6:31730901-31730901	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.495G>A; p.R165R; 6:31732286-31732286	skin	malignant_melanoma	Substitution - coding silent
c.507T>G; p.D169E; 6:31732274-31732274	skin; trunk	malignant_melanoma	Substitution - Missense
c.124A>C; p.N42H; 6:31734179-31734179	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.226G>A; p.D76N; 6:31733885-31733885	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.288G>A; p.L96L; 6:31733660-31733660	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.441C>A; p.P147P; 6:31732340-31732340	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.701A>T; p.E234V; 6:31730867-31730867	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.657C>T; p.F219F; 6:31730911-31730911	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.149G>A; p.R50K; 6:31734154-31734154	liver	carcinoma	Substitution - Missense
c.149G>A; p.R50K; 6:31734154-31734154	liver	carcinoma	Substitution - Missense
c.16C>T; p.P6S; 6:31736285-31736285	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.558A>T; p.I186I; 6:31732223-31732223	skin	malignant_melanoma	Substitution - coding silent
c.595A>G; p.I199V; 6:31730973-31730973	central_nervous_system; brain	glioma	Substitution - Missense
c.12A>G; p.E4E; 6:31736289-31736289	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.599C>T; p.P200L; 6:31730969-31730969	skin	malignant_melanoma	Substitution - Missense
c.609C>T; p.F203F; 6:31730959-31730959	skin	malignant_melanoma	Substitution - coding silent
c.459T>G; p.D153E; 6:31732322-31732322	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.642C>T; p.Y214Y; 6:31730926-31730926	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.10G>C; p.E4Q; 6:31736291-31736291	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.598C>T; p.P200S; 6:31730970-31730970	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.725A>C; p.*242S; 6:31730843-31730843	oesophagus	carcinoma; adenocarcinoma	Nonstop extension
c.100C>A; p.L34M; 6:31734203-31734203	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]