Entrez Gene

Basic Information
Gene ID	11320
Name	MGAT4A
Synonymous	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A;MGAT4A;mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
Definition	N-acetylglucosaminyltransferase IVa\|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa\|UDP-GlcNAc:a-1,3-D-mannoside b-1,4-acetylglucosaminyltransferase IV\|UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminy
Position	2q12
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.866A>G; p.E289G; 2:98645451-98645451	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.243T>G; p.D81E; 2:98678323-98678323	skin	malignant_melanoma	Substitution - Missense
c.401G>T; p.G134V; 2:98675037-98675037	skin	malignant_melanoma	Substitution - Missense
c.1461C>T; p.F487F; 2:98635229-98635229	skin	malignant_melanoma	Substitution - coding silent
c.37G>T; p.A13S; 2:98726296-98726296	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.692G>A; p.R231K; 2:98656358-98656358	skin	malignant_melanoma	Substitution - Missense
c.212G>T; p.R71L; 2:98678354-98678354	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.59delC; p.T20fs*15; 2:98726274-98726274	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.332A>C; p.H111P; 2:98675106-98675106	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1243G>A; p.E415K; 2:98639887-98639887	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.407C>T; p.S136L; 2:98663176-98663176	skin	malignant_melanoma	Substitution - Missense
c.1174C>A; p.P392T; 2:98639956-98639956	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.146G>A; p.R49Q; 2:98678420-98678420	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.70T>G; p.Y24D; 2:98726263-98726263	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.822A>C; p.K274N; 2:98645495-98645495	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.116G>A; p.R39Q; 2:98678450-98678450	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.22G>T; p.V8L; 2:98726311-98726311	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.207C>G; p.F69L; 2:98678359-98678359	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.985C>A; p.L329I; 2:98643958-98643958	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1164C>T; p.I388I; 2:98639966-98639966	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1535G>T; p.R512L; 2:98625769-98625769	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1279G>T; p.D427Y; 2:98639851-98639851	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.414C>T; p.V138V; 2:98663169-98663169	central_nervous_system; brain	glioma	Substitution - coding silent
c.1036_1039delCAGA; p.Q346fs*35; 2:98640210-98640213	breast	carcinoma	Deletion - Frameshift
c.501G>T; p.E167D; 2:98663082-98663082	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.403+3A>G; p.?; 2:98675032-98675032	stomach	adenocarcinoma	Unknown
c.1469G>A; p.G490E; 2:98625835-98625835	NS	malignant_melanoma	Substitution - Missense
c.123C>T; p.F41F; 2:98678443-98678443	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1058G>A; p.R353H; 2:98640191-98640191	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.609C>T; p.G203G; 2:98656441-98656441	breast	carcinoma	Substitution - coding silent
c.1021-1G>T; p.?; 2:98640229-98640229	liver	carcinoma	Unknown
c.1021-1G>T; p.?; 2:98640229-98640229	liver	carcinoma	Unknown
c.1117delC; p.Q373fs*9; 2:98640132-98640132	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift
c.1475T>G; p.F492C; 2:98625829-98625829	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1185G>T; p.E395D; 2:98639945-98639945	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.124C>T; p.L42F; 2:98678442-98678442	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.88G>C; p.G30R; 2:98726245-98726245	breast	carcinoma	Substitution - Missense
c.906G>A; p.A302A; 2:98644037-98644037	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1444T>G; p.L482V; 2:98635246-98635246	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.906G>A; p.A302A; 2:98644037-98644037	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.906G>A; p.A302A; 2:98644037-98644037	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.211C>A; p.R71S; 2:98678355-98678355	liver	carcinoma	Substitution - Missense
c.842C>T; p.S281F; 2:98645475-98645475	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.305C>T; p.S102F; 2:98675133-98675133	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.192G>A; p.T64T; 2:98678374-98678374	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.94+6G>A; p.?; 2:98726233-98726233	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.818T>C; p.I273T; 2:98645499-98645499	breast	carcinoma	Substitution - Missense
c.1165C>T; p.H389Y; 2:98639965-98639965	skin	malignant_melanoma	Substitution - Missense
c.579G>A; p.E193E; 2:98658223-98658223	breast	carcinoma	Substitution - coding silent
c.1565_1566GG>AA; p.W522*; 2:98625738-98625739	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.348G>A; p.L116L; 2:98675090-98675090	skin	malignant_melanoma	Substitution - coding silent
c.626C>T; p.S209L; 2:98656424-98656424	skin	malignant_melanoma	Substitution - Missense
c.403G>A; p.V135I; 2:98675035-98675035	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.605C>A; p.S202Y; 2:98656445-98656445	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.825T>A; p.N275K; 2:98645492-98645492	oesophagus	carcinoma	Substitution - Missense
c.985C>T; p.L329F; 2:98643958-98643958	skin	malignant_melanoma	Substitution - Missense
c.1340G>A; p.G447D; 2:98636578-98636578	breast	carcinoma	Substitution - Missense
c.923T>C; p.I308T; 2:98644020-98644020	salivary_gland; parotid	carcinoma; adenoid_cystic_carcinoma	Substitution - Missense
c.409A>G; p.I137V; 2:98663174-98663174	liver	carcinoma	Substitution - Missense
c.409A>G; p.I137V; 2:98663174-98663174	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1052G>A; p.R351Q; 2:98640197-98640197	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.307C>G; p.L103V; 2:98675131-98675131	stomach	adenocarcinoma	Substitution - Missense
c.548A>T; p.D183V; 2:98658254-98658254	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1124T>C; p.L375P; 2:98640125-98640125	skin; upper_arm	malignant_melanoma	Substitution - Missense
c.255G>A; p.K85K; 2:98678311-98678311	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.50C>T; p.S17F; 2:98726283-98726283	skin	malignant_melanoma	Substitution - Missense
c.468T>G; p.L156L; 2:98663115-98663115	breast	carcinoma	Substitution - coding silent
c.508G>T; p.D170Y; 2:98663075-98663075	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1521C>T; p.P507P; 2:98625783-98625783	breast	carcinoma	Substitution - coding silent
c.277C>A; p.L93M; 2:98675161-98675161	liver	carcinoma	Substitution - Missense
c.1442G>A; p.R481Q; 2:98635248-98635248	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1442G>A; p.R481Q; 2:98635248-98635248	oesophagus	carcinoma	Substitution - Missense
c.1442G>A; p.R481Q; 2:98635248-98635248	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1442G>A; p.R481Q; 2:98635248-98635248	skin	malignant_melanoma	Substitution - Missense
c.1177C>T; p.P393S; 2:98639953-98639953	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1258G>A; p.A420T; 2:98639872-98639872	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.322A>G; p.I108V; 2:98675116-98675116	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.99delA; p.K33fs*2; 2:98678467-98678467	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1398delT; p.F466fs*8; 2:98636520-98636520	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.715A>C; p.N239H; 2:98655504-98655504	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.987C>T; p.L329L; 2:98643956-98643956	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.115C>T; p.R39*; 2:98678451-98678451	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.249G>C; p.L83F; 2:98678317-98678317	urinary_tract; bladder	carcinoma	Substitution - Missense
c.683C>T; p.S228F; 2:98656367-98656367	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1209C>T; p.Y403Y; 2:98639921-98639921	skin	malignant_melanoma	Substitution - coding silent

COSMIC somatic mutation [Top]