Entrez Gene

Basic Information
Gene ID	10625
Name	IVNS1ABP
Synonymous	influenza virus NS1A binding protein;IVNS1ABP;influenza virus NS1A binding protein
Definition	NCX downstream gene 1\|NS1-binding protein\|aryl hydrocarbon receptor-associated 3\|aryl hydrocarbon receptor-associated protein 3\|influenza virus NS1A-binding protein\|kelch-like family member 39
Position	1q25.1-q31.1
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1042G>A; p.E348K; 1:185301050-185301050	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1043A>G; p.E348G; 1:185301049-185301049	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1042G>A; p.E348K; 1:185301050-185301050	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.287A>C; p.K96T; 1:185308870-185308870	liver	carcinoma	Substitution - Missense
c.287A>C; p.K96T; 1:185308870-185308870	liver	carcinoma	Substitution - Missense
c.893C>G; p.S298*; 1:185301436-185301436	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1858C>T; p.L620L; 1:185298106-185298106	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1711C>G; p.H571D; 1:185298253-185298253	breast	carcinoma	Substitution - Missense
c.1370G>A; p.G457E; 1:185300130-185300130	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.340A>C; p.M114L; 1:185308817-185308817	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1798G>T; p.G600W; 1:185298166-185298166	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1403T>C; p.V468A; 1:185300097-185300097	large_intestine; colon	carcinoma	Substitution - Missense
c.1403T>C; p.V468A; 1:185300097-185300097	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1621T>G; p.L541V; 1:185299764-185299764	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.450G>A; p.L150L; 1:185307570-185307570	oesophagus	carcinoma	Substitution - coding silent
c.1300G>C; p.E434Q; 1:185300286-185300286	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1800G>C; p.G600G; 1:185298164-185298164	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.346C>A; p.R116R; 1:185308811-185308811	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.807C>T; p.S269S; 1:185301522-185301522	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1093G>C; p.E365Q; 1:185300999-185300999	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.807C>T; p.S269S; 1:185301522-185301522	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.318T>C; p.Y106Y; 1:185308839-185308839	liver	carcinoma	Substitution - coding silent
c.1148G>A; p.R383Q; 1:185300531-185300531	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1124G>C; p.G375A; 1:185300555-185300555	prostate	carcinoma	Substitution - Missense
c.380C>A; p.S127Y; 1:185307640-185307640	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1148G>A; p.R383Q; 1:185300531-185300531	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.807C>A; p.S269R; 1:185301522-185301522	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.94T>C; p.C32R; 1:185309400-185309400	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.94T>C; p.C32R; 1:185309400-185309400	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.222A>C; p.K74N; 1:185309062-185309062	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.94T>C; p.C32R; 1:185309400-185309400	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1805C>T; p.A602V; 1:185298159-185298159	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1550T>A; p.I517N; 1:185299835-185299835	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.552_553insA; p.N185fs*21; 1:185307118-185307119	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Insertion - Frameshift
c.1904C>T; p.P635L; 1:185298060-185298060	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1916T>G; p.I639S; 1:185298048-185298048	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.1033G>A; p.E345K; 1:185301059-185301059	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1799G>T; p.G600V; 1:185298165-185298165	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.447G>A; p.L149L; 1:185307573-185307573	liver	carcinoma	Substitution - coding silent
c.447G>A; p.L149L; 1:185307573-185307573	liver	carcinoma	Substitution - coding silent
c.447G>A; p.L149L; 1:185307573-185307573	liver	carcinoma	Substitution - coding silent
c.1398C>T; p.Y466Y; 1:185300102-185300102	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1683_1686delGTTT; p.F562fs*26; 1:185298278-185298281	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.68A>G; p.N23S; 1:185309426-185309426	haematopoietic_and_lymphoid_tissue; abdomen	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.873C>T; p.I291I; 1:185301456-185301456	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.949C>T; p.L317F; 1:185301143-185301143	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1471T>C; p.L491L; 1:185300029-185300029	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1096A>G; p.M366V; 1:185300996-185300996	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.341T>C; p.M114T; 1:185308816-185308816	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.630A>C; p.G210G; 1:185307041-185307041	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1220G>A; p.R407Q; 1:185300459-185300459	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.291A>T; p.A97A; 1:185308866-185308866	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1417C>T; p.P473S; 1:185300083-185300083	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1417C>T; p.P473S; 1:185300083-185300083	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1095G>A; p.E365E; 1:185300997-185300997	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1918T>A; p.F640I; 1:185298046-185298046	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1358G>A; p.R453H; 1:185300228-185300228	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1291A>C; p.S431R; 1:185300295-185300295	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1142G>T; p.C381F; 1:185300537-185300537	skin	malignant_melanoma	Substitution - Missense
c.1807A>G; p.T603A; 1:185298157-185298157	liver	carcinoma	Substitution - Missense
c.1776G>A; p.M592I; 1:185298188-185298188	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.481T>G; p.L161V; 1:185307539-185307539	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.460G>A; p.D154N; 1:185307560-185307560	urinary_tract; bladder	carcinoma	Substitution - Missense
c.933A>G; p.I311M; 1:185301159-185301159	liver	carcinoma	Substitution - Missense
c.1894G>T; p.E632*; 1:185298070-185298070	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1878T>G; p.Y626*; 1:185298086-185298086	prostate	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1426C>T; p.Q476*; 1:185300074-185300074	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1163A>G; p.Y388C; 1:185300516-185300516	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.621G>T; p.W207C; 1:185307050-185307050	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1382T>A; p.L461Q; 1:185300118-185300118	liver	carcinoma	Substitution - Missense
c.1382T>A; p.L461Q; 1:185300118-185300118	liver	carcinoma	Substitution - Missense
c.1253_1254delAT; p.Y418fs*11; 1:185300332-185300333	breast	carcinoma	Deletion - Frameshift
c.1501C>T; p.R501W; 1:185299999-185299999	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1501C>T; p.R501W; 1:185299999-185299999	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1501C>T; p.R501W; 1:185299999-185299999	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.1431A>G; p.K477K; 1:185300069-185300069	skin	malignant_melanoma	Substitution - coding silent
c.1803T>G; p.I601M; 1:185298161-185298161	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1617G>A; p.W539*; 1:185299768-185299768	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.765+2T>C; p.?; 1:185305534-185305534	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.606G>A; p.V202V; 1:185307065-185307065	breast	carcinoma	Substitution - coding silent
c.647T>C; p.L216P; 1:185307024-185307024	skin	malignant_melanoma	Substitution - Missense
c.381T>A; p.S127S; 1:185307639-185307639	breast	carcinoma	Substitution - coding silent
c.1914G>T; p.K638N; 1:185298050-185298050	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1914G>T; p.K638N; 1:185298050-185298050	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1489C>T; p.P497S; 1:185300011-185300011	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1635G>T; p.M545I; 1:185299750-185299750	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.470T>A; p.I157N; 1:185307550-185307550	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.861T>C; p.H287H; 1:185301468-185301468	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1155C>T; p.V385V; 1:185300524-185300524	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1798G>A; p.G600R; 1:185298166-185298166	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1912A>C; p.K638Q; 1:185298052-185298052	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.203A>G; p.H68R; 1:185309081-185309081	breast	carcinoma	Substitution - Missense
c.547G>A; p.E183K; 1:185307124-185307124	urinary_tract; bladder	carcinoma	Substitution - Missense
c.413G>A; p.R138Q; 1:185307607-185307607	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.494C>T; p.S165F; 1:185307526-185307526	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1864A>G; p.T622A; 1:185298100-185298100	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1387G>T; p.G463*; 1:185300113-185300113	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.1631C>A; p.P544H; 1:185299754-185299754	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.329A>G; p.K110R; 1:185308828-185308828	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.875T>C; p.V292A; 1:185301454-185301454	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.96T>A; p.C32*; 1:185309398-185309398	ovary	carcinoma; serous_carcinoma	Substitution - Nonsense
c.523A>T; p.R175W; 1:185307497-185307497	breast	carcinoma	Substitution - Missense
c.1445G>C; p.C482S; 1:185300055-185300055	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.874G>A; p.V292I; 1:185301455-185301455	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1835G>T; p.G612V; 1:185298129-185298129	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.888G>C; p.K296N; 1:185301441-185301441	breast	carcinoma	Substitution - Missense
c.1181A>G; p.H394R; 1:185300498-185300498	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.941T>C; p.V314A; 1:185301151-185301151	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.840T>G; p.A280A; 1:185301489-185301489	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1843G>A; p.D615N; 1:185298121-185298121	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1843G>A; p.D615N; 1:185298121-185298121	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1211C>T; p.P404L; 1:185300468-185300468	skin	malignant_melanoma	Substitution - Missense
c.490A>T; p.I164F; 1:185307530-185307530	skin	malignant_melanoma	Substitution - Missense
c.1225C>G; p.Q409E; 1:185300454-185300454	urinary_tract; bladder	carcinoma	Substitution - Missense
c.97G>C; p.D33H; 1:185309397-185309397	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1865C>T; p.T622M; 1:185298099-185298099	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.97G>C; p.D33H; 1:185309397-185309397	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.670T>C; p.Y224H; 1:185305631-185305631	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1041C>T; p.I347I; 1:185301051-185301051	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1297G>T; p.G433*; 1:185300289-185300289	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.347G>A; p.R116Q; 1:185308810-185308810	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1715C>T; p.A572V; 1:185298249-185298249	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.792T>C; p.H264H; 1:185301537-185301537	skin	malignant_melanoma	Substitution - coding silent
c.792T>C; p.H264H; 1:185301537-185301537	skin	malignant_melanoma	Substitution - coding silent
c.953A>G; p.H318R; 1:185301139-185301139	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.620_621GG>AC; p.W207Y; 1:185307050-185307051	skin; mucosal	malignant_melanoma	Substitution - Missense
c.1232C>T; p.A411V; 1:185300447-185300447	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.383G>C; p.R128T; 1:185307637-185307637	oesophagus	carcinoma	Substitution - Missense
c.1055C>T; p.S352F; 1:185301037-185301037	kidney	other; neoplasm	Substitution - Missense

COSMIC somatic mutation [Top]