Entrez Gene

Basic Information
Gene ID	10572
Name	SIVA1
Synonymous	SIVA1, apoptosis-inducing factor;SIVA1;SIVA1, apoptosis-inducing factor
Definition	CD27-binding (Siva) protein\|apoptosis regulatory protein Siva
Position	14q32.33
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.279C>T; p.R93R; 14:104755790-104755790	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.189C>T; p.A63A; 14:104755700-104755700	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.189C>T; p.A63A; 14:104755700-104755700	thyroid	other; neoplasm	Substitution - coding silent
c.189C>T; p.A63A; 14:104755700-104755700	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.255G>T; p.Q85H; 14:104755766-104755766	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.165C>T; p.D55D; 14:104755676-104755676	skin	malignant_melanoma	Substitution - coding silent
c.165C>T; p.D55D; 14:104755676-104755676	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.215A>C; p.K72T; 14:104755726-104755726	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.297G>A; p.G99G; 14:104755808-104755808	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.297G>A; p.G99G; 14:104755808-104755808	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.490A>T; p.K164*; 14:104759447-104759447	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.141C>T; p.F47F; 14:104755652-104755652	skin	malignant_melanoma	Substitution - coding silent
c.275G>A; p.G92D; 14:104755786-104755786	skin	malignant_melanoma	Substitution - Missense
c.275G>A; p.G92D; 14:104755786-104755786	skin	malignant_melanoma	Substitution - Missense
c.119-4_119-3CC>TT; p.?; 14:104755626-104755627	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.168C>G; p.H56Q; 14:104755679-104755679	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.12G>T; p.R4R; 14:104753213-104753213	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.330G>A; p.A110A; 14:104756620-104756620	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.242C>T; p.A81V; 14:104755753-104755753	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.229G>A; p.G77R; 14:104755740-104755740	skin	malignant_melanoma	Substitution - Missense
c.441C>T; p.S147S; 14:104756731-104756731	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.169G>A; p.V57M; 14:104755680-104755680	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.441C>T; p.S147S; 14:104756731-104756731	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.329C>T; p.A110V; 14:104756619-104756619	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.46C>T; p.L16F; 14:104753247-104753247	prostate	carcinoma	Substitution - Missense
c.217C>T; p.P73S; 14:104755728-104755728	liver	carcinoma	Substitution - Missense
c.397G>A; p.A133T; 14:104756687-104756687	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.405C>T; p.C135C; 14:104756695-104756695	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.368_369GG>AA; p.G123E; 14:104756658-104756659	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.130C>T; p.R44*; 14:104755641-104755641	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.247C>T; p.R83C; 14:104755758-104755758	central_nervous_system; brain	glioma	Substitution - Missense
c.145G>A; p.G49R; 14:104755656-104755656	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]