| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10417 |
Name | SPON2 |
Synonymous | spondin 2, extracellular matrix protein;SPON2;spondin 2, extracellular matrix protein |
Definition | differentially expressed in cancerous and non-cancerous lung cells 1|spondin-2 |
Position | 4p16.3 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.268G>A; p.V90I; 4:1171439-1171439 |
skin | malignant_melanoma | Substitution - Missense |
c.939G>A; p.G313G; 4:1167529-1167529 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - coding silent |
c.314C>A; p.A105E; 4:1171393-1171393 |
bone | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Substitution - Missense |
c.642G>A; p.T214T; 4:1170571-1170571 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.882delG; p.R295fs*>37; 4:1167586-1167586 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Deletion - Frameshift |
c.289T>A; p.F97I; 4:1171418-1171418 |
kidney | carcinoma; papillary_renal_cell_carcinoma | Substitution - Missense |
c.52C>T; p.L18F; 4:1172020-1172020 |
pancreas | carcinoma; adenocarcinoma | Substitution - Missense |
c.413C>A; p.A138E; 4:1171294-1171294 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.727C>T; p.R243W; 4:1170486-1170486 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.738G>T; p.Q246H; 4:1170475-1170475 |
kidney | carcinoma; papillary_renal_cell_carcinoma | Substitution - Missense |
c.100A>G; p.I34V; 4:1171972-1171972 |
skin | malignant_melanoma | Substitution - Missense |
c.238G>A; p.D80N; 4:1171469-1171469 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.734G>A; p.R245Q; 4:1170479-1170479 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.825G>A; p.P275P; 4:1167643-1167643 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia | Substitution - coding silent |
c.164C>T; p.A55V; 4:1171908-1171908 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.64C>T; p.L22F; 4:1172008-1172008 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.297G>A; p.E99E; 4:1171410-1171410 |
bone | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Substitution - coding silent |
c.290_291insT; p.A98fs*167; 4:1171416-1171417 |
soft_tissue; fat | liposarcoma; myxoid-round_cell | Insertion - Frameshift |
c.713G>C; p.R238T; 4:1170500-1170500 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.365C>A; p.A122E; 4:1171342-1171342 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.365C>A; p.A122E; 4:1171342-1171342 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.365C>A; p.A122E; 4:1171342-1171342 |
thyroid | other; neoplasm | Substitution - Missense |
c.365C>A; p.A122E; 4:1171342-1171342 |
thyroid | other; neoplasm | Substitution - Missense |
c.365C>A; p.A122E; 4:1171342-1171342 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.414G>A; p.A138A; 4:1171293-1171293 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - coding silent |
c.96G>A; p.E32E; 4:1171976-1171976 |
thyroid | other; neoplasm | Substitution - coding silent |
c.96G>A; p.E32E; 4:1171976-1171976 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia | Substitution - coding silent |
c.96G>A; p.E32E; 4:1171976-1171976 |
thyroid | other; neoplasm | Substitution - coding silent |
c.493G>A; p.V165M; 4:1171142-1171142 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.382G>A; p.A128T; 4:1171325-1171325 |
large_intestine; colon | carcinoma | Substitution - Missense |
c.200C>T; p.A67V; 4:1171872-1171872 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.382G>A; p.A128T; 4:1171325-1171325 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.385G>A; p.V129I; 4:1171322-1171322 |
oesophagus; middle_third | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.295G>A; p.E99K; 4:1171412-1171412 |
thyroid | carcinoma | Substitution - Missense |
c.523C>T; p.R175C; 4:1171112-1171112 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.225C>T; p.A75A; 4:1171482-1171482 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.339G>A; p.A113A; 4:1171368-1171368 |
skin | malignant_melanoma | Substitution - coding silent |
c.852G>C; p.S284S; 4:1167616-1167616 |
breast | carcinoma | Substitution - coding silent |
c.132C>A; p.S44R; 4:1171940-1171940 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.340G>A; p.G114R; 4:1171367-1171367 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.358G>A; p.V120M; 4:1171349-1171349 |
oesophagus | carcinoma; adenocarcinoma | Substitution - Missense |
c.724G>C; p.V242L; 4:1170489-1170489 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.927C>T; p.P309P; 4:1167541-1167541 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - coding silent |
c.599_600delCC; p.P200fs*64; 4:1171035-1171036 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.703C>A; p.P235T; 4:1170510-1170510 |
pancreas | carcinoma | Substitution - Missense |
c.758C>T; p.P253L; 4:1170455-1170455 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.212C>T; p.S71L; 4:1171860-1171860 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.304G>A; p.E102K; 4:1171403-1171403 |
bone | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Substitution - Missense |
c.304G>A; p.E102K; 4:1171403-1171403 |
thyroid | carcinoma | Substitution - Missense |
c.190C>T; p.R64C; 4:1171882-1171882 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.20C>T; p.A7V; 4:1172052-1172052 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.762C>T; p.P254P; 4:1170451-1170451 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.201G>A; p.A67A; 4:1171871-1171871 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.201G>A; p.A67A; 4:1171871-1171871 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.805G>A; p.A269T; 4:1170408-1170408 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.167T>C; p.F56S; 4:1171905-1171905 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.167T>C; p.F56S; 4:1171905-1171905 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.66C>G; p.L22L; 4:1172006-1172006 |
urinary_tract; bladder | carcinoma; transitional_cell_carcinoma | Substitution - coding silent |
c.637-3C>T; p.?; 4:1170579-1170579 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Unknown |
c.22G>A; p.A8T; 4:1172050-1172050 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.449C>T; p.S150L; 4:1171186-1171186 |
skin; trunk | malignant_melanoma | Substitution - Missense |
c.871G>T; p.G291C; 4:1167597-1167597 |
upper_aerodigestive_tract; mouth | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.871G>T; p.G291C; 4:1167597-1167597 |
upper_aerodigestive_tract; mouth | carcinoma | Substitution - Missense |
c.112A>G; p.R38G; 4:1171960-1171960 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.119T>C; p.L40P; 4:1171953-1171953 |
thyroid | other; neoplasm | Substitution - Missense |
c.347C>T; p.A116V; 4:1171360-1171360 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.220_220+1GG>TT; p.?; 4:1171851-1171852 |
large_intestine; colon | carcinoma; adenocarcinoma | Unknown |