| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10273 |
Name | STUB1 |
Synonymous | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase;STUB1;STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase |
Definition | CLL-associated antigen KW-8|E3 ubiquitin-protein ligase CHIP|antigen NY-CO-7|carboxy terminus of Hsp70-interacting protein|heat shock protein A binding protein 2 (c-terminal)|serologically defined colon cancer antigen 7 |
Position | 16p13.3 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.571A>C; p.S191R; 16:681839-681839 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.373A>G; p.K125E; 16:681452-681452 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.597C>T; p.C199C; 16:681865-681865 |
breast | carcinoma | Substitution - coding silent |
c.840C>T; p.L280L; 16:682417-682417 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.400G>A; p.D134N; 16:681479-681479 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.731G>A; p.C244Y; 16:682226-682226 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.460C>T; p.R154C; 16:681539-681539 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.629A>C; p.D210A; 16:682036-682036 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.331G>C; p.D111H; 16:681323-681323 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.294C>A; p.F98L; 16:681286-681286 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.535G>C; p.E179Q; 16:681803-681803 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.535G>C; p.E179Q; 16:681803-681803 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.613-1G>T; p.?; 16:682019-682019 |
large_intestine; colon | carcinoma; adenocarcinoma | Unknown |
c.613-1G>T; p.?; 16:682019-682019 |
kidney | carcinoma; papillary_renal_cell_carcinoma | Unknown |
c.786+8delC; p.?; 16:682289-682289 |
soft_tissue; striated_muscle | rhabdomyosarcoma; alveolar | Unknown |
c.658G>A; p.E220K; 16:682065-682065 |
breast | carcinoma | Substitution - Missense |
c.27C>T; p.G9G; 16:680552-680552 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.426_428delGAA; p.K145delK; 16:681505-681507 |
large_intestine; caecum | carcinoma; adenocarcinoma | Deletion - In frame |
c.426_428delGAA; p.K145delK; 16:681505-681507 |
breast | carcinoma | Deletion - In frame |
c.424G>A; p.A142T; 16:681503-681503 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.555G>T; p.E185D; 16:681823-681823 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.875C>T; p.A292V; 16:682452-682452 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.458G>A; p.R153Q; 16:681537-681537 |
skin | malignant_melanoma | Substitution - Missense |
c.796C>T; p.H266Y; 16:682373-682373 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.863_865delAGG; p.E288delE; 16:682440-682442 |
ovary | carcinoma | Deletion - In frame |
c.788G>A; p.R263H; 16:682365-682365 |
thyroid | carcinoma | Substitution - Missense |
c.285G>A; p.K95K; 16:681277-681277 |
skin | malignant_melanoma | Substitution - coding silent |
c.225G>A; p.Q75Q; 16:681217-681217 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.194A>T; p.N65I; 16:681186-681186 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.710T>C; p.F237S; 16:682205-682205 |
upper_aerodigestive_tract; mouth | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.547A>C; p.N183H; 16:681815-681815 |
oesophagus | carcinoma; adenocarcinoma | Substitution - Missense |
c.738G>A; p.T246T; 16:682233-682233 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.717G>C; p.L239L; 16:682212-682212 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.760C>A; p.R254S; 16:682255-682255 |
oesophagus | carcinoma; adenocarcinoma | Substitution - Missense |
c.461G>A; p.R154H; 16:681540-681540 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.874G>A; p.A292T; 16:682451-682451 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Substitution - Missense |
c.433A>C; p.K145Q; 16:681512-681512 |
adrenal_gland; adrenal_gland | adrenal_cortical_carcinoma; non_functioning | Substitution - Missense |
c.433A>C; p.K145Q; 16:681512-681512 |
large_intestine; rectum | adenoma | Substitution - Missense |
c.341T>C; p.I114T; 16:681333-681333 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.690_691insAGT; p.Y230_L231insS; 16:682185-682186 |
large_intestine; colon | carcinoma; adenocarcinoma | Insertion - In frame |
c.766G>C; p.D256H; 16:682261-682261 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.123G>A; p.K41K; 16:680648-680648 |
stomach | carcinoma; diffuse_adenocarcinoma | Substitution - coding silent |
c.394G>A; p.G132R; 16:681473-681473 |
pancreas | carcinoma; acinar_carcinoma | Substitution - Missense |
c.636C>T; p.D212D; 16:682043-682043 |
oesophagus; middle_third | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.378G>A; p.E126E; 16:681457-681457 |
breast | carcinoma | Substitution - coding silent |
c.454G>A; p.E152K; 16:681533-681533 |
skin | malignant_melanoma | Substitution - Missense |
c.674G>A; p.R225Q; 16:682169-682169 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.513G>A; p.A171A; 16:681592-681592 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.326G>A; p.S109N; 16:681318-681318 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |