| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10197 |
Name | PSME3 |
Synonymous | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki);PSME3;proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) |
Definition | 11S regulator complex gamma subunit|11S regulator complex subunit gamma|Ki antigen|Ki nuclear autoantigen|PA28 gamma variant 5|REG gamma-3|activator of multicatalytic protease subunit 3|epididymis secretory protein Li 283|proteasome activator 28 subunit g |
Position | 17q21 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.676G>T; p.E226*; 17:42839333-42839333 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.480A>G; p.I160M; 17:42838766-42838766 |
kidney | other; neoplasm | Substitution - Missense |
c.113T>G; p.L38*; 17:42834552-42834552 |
skin | malignant_melanoma | Substitution - Nonsense |
c.94A>G; p.N32D; 17:42834533-42834533 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.756C>T; p.I252I; 17:42841530-42841530 |
skin | malignant_melanoma | Substitution - coding silent |
c.425_426delAT; p.I143fs*3; 17:42838711-42838712 |
stomach | carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable | Deletion - Frameshift |
c.465C>T; p.L155L; 17:42838751-42838751 |
skin | malignant_melanoma | Substitution - coding silent |
c.241G>A; p.G81S; 17:42834874-42834874 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.625T>C; p.Y209H; 17:42839155-42839155 |
stomach | carcinoma; intestinal_adenocarcinoma | Substitution - Missense |
c.687C>T; p.S229S; 17:42839344-42839344 |
NS | NS | Substitution - coding silent |
c.172A>T; p.I58F; 17:42834805-42834805 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.57_58GG>AA; p.E20K; 17:42834358-42834359 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.636+1_636+4delGTAA; p.?; 17:42839167-42839170 |
large_intestine | carcinoma; adenocarcinoma | Unknown |
c.373G>A; p.E125K; 17:42838173-42838173 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.122T>G; p.L41R; 17:42834561-42834561 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.654C>T; p.T218T; 17:42839311-42839311 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.431G>A; p.C144Y; 17:42838717-42838717 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.506C>T; p.S169F; 17:42838792-42838792 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.691C>T; p.R231W; 17:42839348-42839348 |
cervix | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.691C>T; p.R231W; 17:42839348-42839348 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.337C>T; p.Q113*; 17:42838137-42838137 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.460C>T; p.Q154*; 17:42838746-42838746 |
central_nervous_system; brain | glioma | Substitution - Nonsense |
c.221A>G; p.N74S; 17:42834854-42834854 |
skin | malignant_melanoma | Substitution - Missense |
c.636+1_636+4delGTAA; p.?; 17:42839167-42839170 |
large_intestine | carcinoma; adenocarcinoma | Unknown |
c.155T>G; p.I52S; 17:42834788-42834788 |
prostate | carcinoma; adenocarcinoma | Substitution - Missense |
c.331A>G; p.S111G; 17:42838131-42838131 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.517G>A; p.E173K; 17:42838948-42838948 |
skin | malignant_melanoma | Substitution - Missense |
c.620C>A; p.A207D; 17:42839150-42839150 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.780C>T; p.S260S; 17:42841554-42841554 |
breast | carcinoma | Substitution - coding silent |
c.190C>A; p.L64I; 17:42834823-42834823 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.438C>A; p.D146E; 17:42838724-42838724 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.284C>T; p.A95V; 17:42837689-42837689 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.418G>A; p.G140S; 17:42838704-42838704 |
liver | carcinoma; hepatocellular_carcinoma | Substitution - Missense |
c.145A>T; p.I49F; 17:42834778-42834778 |
liver | carcinoma | Substitution - Missense |