Entrez Gene

Basic Information
Gene ID	10152
Name	ABI2
Synonymous	abl-interactor 2;ABI2;abl-interactor 2
Definition	abelson interactor 2\|abl binding protein 3\|abl interactor 2\|abl-interacting protein 1 (SH3-containing protein)\|abl-interactor protein 2b\|arg protein tyrosine kinase-binding protein\|arg-binding protein 1
Position	2q33
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1224G>A; p.P408P; 2:203417053-203417053	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.917G>A; p.R306H; 2:203402660-203402660	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.216C>T; p.V72V; 2:203366975-203366975	skin	malignant_melanoma	Substitution - coding silent
c.1235G>A; p.R412H; 2:203417064-203417064	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.846G>A; p.Q282Q; 2:203402589-203402589	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5C>T; p.A2V; 2:203328519-203328519	skin	malignant_melanoma	Substitution - Missense
c.1402G>C; p.E468Q; 2:203427326-203427326	breast	carcinoma	Substitution - Missense
c.1401T>C; p.V467V; 2:203427325-203427325	prostate	carcinoma	Substitution - coding silent
c.525C>T; p.P175P; 2:203391108-203391108	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.95A>C; p.Y32S; 2:203328609-203328609	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.95A>C; p.Y32S; 2:203328609-203328609	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.529A>G; p.S177G; 2:203391112-203391112	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.577C>T; p.R193C; 2:203394716-203394716	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1084G>T; p.D362Y; 2:203416913-203416913	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1374G>A; p.V458V; 2:203427298-203427298	liver	carcinoma	Substitution - coding silent
c.218T>G; p.L73R; 2:203366977-203366977	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.218T>G; p.L73R; 2:203366977-203366977	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.22C>T; p.L8L; 2:203328536-203328536	pancreas	carcinoma	Substitution - coding silent
c.533C>T; p.P178L; 2:203391116-203391116	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.403C>T; p.R135C; 2:203380325-203380325	breast	carcinoma	Substitution - Missense
c.403C>T; p.R135C; 2:203380325-203380325	skin; trunk	malignant_melanoma	Substitution - Missense
c.858G>T; p.M286I; 2:203402601-203402601	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.669G>T; p.V223V; 2:203394808-203394808	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.568T>C; p.S190P; 2:203394707-203394707	thyroid	carcinoma	Substitution - Missense
c.672G>A; p.R224R; 2:203394811-203394811	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.692G>T; p.R231I; 2:203394831-203394831	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.870C>G; p.A290A; 2:203402613-203402613	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.903G>A; p.S301S; 2:203402646-203402646	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.660G>C; p.Q220H; 2:203394799-203394799	pancreas	carcinoma	Substitution - Missense
c.61G>C; p.D21H; 2:203328575-203328575	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1342G>A; p.D448N; 2:203427266-203427266	breast	carcinoma	Substitution - Missense
c.1234C>T; p.R412C; 2:203417063-203417063	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.757C>T; p.R253*; 2:203395705-203395705	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.757C>T; p.R253*; 2:203395705-203395705	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.171C>T; p.S57S; 2:203366930-203366930	skin	malignant_melanoma	Substitution - coding silent
c.1329C>G; p.I443M; 2:203427253-203427253	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1382T>C; p.L461P; 2:203427306-203427306	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.404G>A; p.R135H; 2:203380326-203380326	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Substitution - Missense
c.436C>A; p.L146I; 2:203380358-203380358	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.145G>T; p.E49*; 2:203366904-203366904	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.145G>T; p.E49*; 2:203366904-203366904	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.923C>A; p.P308H; 2:203402666-203402666	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1414C>T; p.H472Y; 2:203427338-203427338	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.687T>A; p.N229K; 2:203394826-203394826	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.320G>A; p.R107K; 2:203380242-203380242	urinary_tract; bladder	carcinoma	Substitution - Missense
c.984G>T; p.Q328H; 2:203402727-203402727	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1308A>G; p.E436E; 2:203427232-203427232	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.499C>T; p.R167C; 2:203391082-203391082	pancreas	carcinoma	Substitution - Missense
c.875G>A; p.R292H; 2:203402618-203402618	prostate	carcinoma	Substitution - Missense
c.578G>A; p.R193H; 2:203394717-203394717	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.517C>G; p.Q173E; 2:203391100-203391100	breast	carcinoma	Substitution - Missense
c.82C>A; p.R28R; 2:203328596-203328596	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1347T>G; p.G449G; 2:203427271-203427271	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.322G>T; p.E108*; 2:203380244-203380244	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.469A>G; p.T157A; 2:203391052-203391052	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1386T>G; p.F462L; 2:203427310-203427310	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.730A>G; p.S244G; 2:203395678-203395678	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.730A>G; p.S244G; 2:203395678-203395678	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.860A>C; p.N287T; 2:203402603-203402603	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.584T>C; p.L195P; 2:203394723-203394723	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.901T>A; p.S301T; 2:203402644-203402644	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1088C>T; p.T363I; 2:203416917-203416917	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.651C>G; p.P217P; 2:203394790-203394790	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.393_394insACGACC; p.E131_R132insTT; 2:203380315-203380316	stomach	carcinoma; intestinal_adenocarcinoma	Insertion - In frame
c.564G>A; p.R188R; 2:203394703-203394703	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.564G>A; p.R188R; 2:203394703-203394703	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1405T>C; p.S469P; 2:203427329-203427329	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1186G>A; p.V396I; 2:203417015-203417015	liver	carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]