Entrez Gene

Basic Information
Gene ID	10097
Name	ACTR2
Synonymous	ARP2 actin-related protein 2 homolog (yeast);ACTR2;ARP2 actin-related protein 2 homolog (yeast)
Definition	actin-like protein 2\|actin-related protein 2
Position	2p14
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.424G>A; p.A142T; 2:65251075-65251075	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.514G>A; p.G172S; 2:65253793-65253793	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.505G>A; p.V169I; 2:65253784-65253784	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.971T>C; p.L324P; 2:65265132-65265132	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.645G>T; p.M215I; 2:65255604-65255604	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.583A>G; p.K195E; 2:65253862-65253862	liver	carcinoma	Substitution - Missense
c.583A>G; p.K195E; 2:65253862-65253862	liver	carcinoma	Substitution - Missense
c.728C>A; p.S243Y; 2:65255687-65255687	breast	carcinoma	Substitution - Missense
c.381G>C; p.M127I; 2:65251032-65251032	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1124G>A; p.R375Q; 2:65268673-65268673	skin	malignant_melanoma	Substitution - Missense
c.1124G>A; p.R375Q; 2:65268673-65268673	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.582C>T; p.I194I; 2:65253861-65253861	breast	carcinoma	Substitution - coding silent
c.803C>T; p.P268L; 2:65261314-65261314	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.480A>G; p.G160G; 2:65253759-65253759	breast	carcinoma	Substitution - coding silent
c.893A>T; p.Y298F; 2:65265054-65265054	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.151G>T; p.E51*; 2:65239954-65239954	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.640C>T; p.R214C; 2:65255599-65255599	skin	malignant_melanoma	Substitution - Missense
c.911C>A; p.S304Y; 2:65265072-65265072	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.973T>C; p.Y325H; 2:65265134-65265134	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1138G>T; p.E380*; 2:65268687-65268687	NS	NS	Substitution - Nonsense
c.348A>C; p.P116P; 2:65246712-65246712	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1028G>A; p.R343H; 2:65268577-65268577	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.194G>T; p.R65L; 2:65246558-65246558	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1173G>T; p.V391V; 2:65268722-65268722	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.288G>A; p.E96E; 2:65246652-65246652	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.550A>G; p.I184V; 2:65253829-65253829	liver	carcinoma	Substitution - Missense
c.550A>G; p.I184V; 2:65253829-65253829	liver	carcinoma	Substitution - Missense
c.239G>A; p.R80Q; 2:65246603-65246603	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.931C>T; p.P311S; 2:65265092-65265092	skin	malignant_melanoma	Substitution - Missense
c.67G>T; p.A23S; 2:65239870-65239870	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.773G>A; p.R258K; 2:65261284-65261284	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1181G>A; p.R394Q; 2:65268730-65268730	breast	carcinoma	Substitution - Missense
c.819T>C; p.V273V; 2:65261330-65261330	liver	carcinoma	Substitution - coding silent
c.684G>A; p.E228E; 2:65255643-65255643	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.856A>G; p.I286V; 2:65261367-65261367	prostate	carcinoma	Substitution - Missense
c.983G>T; p.R328L; 2:65265144-65265144	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1046G>A; p.R349H; 2:65268595-65268595	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.610T>C; p.F204L; 2:65255569-65255569	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.384T>C; p.F128F; 2:65251035-65251035	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.268G>A; p.D90N; 2:65246632-65246632	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.537C>G; p.T179T; 2:65253816-65253816	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.92T>A; p.I31N; 2:65239895-65239895	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.998A>C; p.D333A; 2:65265159-65265159	breast	carcinoma	Substitution - Missense
c.245G>C; p.W82S; 2:65246609-65246609	ovary	other; neoplasm	Substitution - Missense
c.748C>T; p.R250C; 2:65261259-65261259	kidney	other; neoplasm	Substitution - Missense
c.748C>T; p.R250C; 2:65261259-65261259	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.739C>T; p.P247S; 2:65261250-65261250	skin	malignant_melanoma	Substitution - Missense
c.1095G>C; p.M365I; 2:65268644-65268644	ovary	other; neoplasm	Substitution - Missense
c.1095G>C; p.M365I; 2:65268644-65268644	ovary	other; neoplasm	Substitution - Missense
c.769G>A; p.E257K; 2:65261280-65261280	oesophagus	carcinoma	Substitution - Missense
c.825A>T; p.G275G; 2:65261336-65261336	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1062A>G; p.V354V; 2:65268611-65268611	liver	carcinoma	Substitution - coding silent
c.125G>C; p.R42T; 2:65239928-65239928	breast	carcinoma	Substitution - Missense
c.886G>A; p.E296K; 2:65265047-65265047	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]