Entrez Gene

Basic Information
Gene ID	10096
Name	ACTR3
Synonymous	ARP3 actin-related protein 3 homolog (yeast);ACTR3;ARP3 actin-related protein 3 homolog (yeast)
Definition	actin-like protein 3\|actin-related protein 3
Position	2q14.1
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.999T>C; p.R333R; 2:113951767-113951767	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1087A>G; p.I363V; 2:113955632-113955632	urinary_tract; bladder	carcinoma	Substitution - Missense
c.561C>T; p.G187G; 2:113939979-113939979	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.657A>C; p.Q219H; 2:113940075-113940075	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.998G>A; p.R333H; 2:113951766-113951766	liver	carcinoma	Substitution - Missense
c.998G>A; p.R333H; 2:113951766-113951766	liver	carcinoma	Substitution - Missense
c.998G>A; p.R333H; 2:113951766-113951766	liver	carcinoma	Substitution - Missense
c.67G>T; p.G23*; 2:113913194-113913194	liver	carcinoma	Substitution - Nonsense
c.841A>C; p.I281L; 2:113942342-113942342	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.439C>G; p.L147V; 2:113934285-113934285	breast	carcinoma	Substitution - Missense
c.331C>G; p.L111V; 2:113927450-113927450	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.679G>C; p.V227L; 2:113940097-113940097	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.391T>G; p.F131V; 2:113931355-113931355	pancreas	carcinoma	Substitution - Missense
c.856G>T; p.E286*; 2:113942357-113942357	breast	carcinoma	Substitution - Nonsense
c.391T>G; p.F131V; 2:113931355-113931355	pancreas	carcinoma	Substitution - Missense
c.1161+10A>G; p.?; 2:113955716-113955716	breast	carcinoma	Unknown
c.494G>A; p.G165D; 2:113934340-113934340	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.593G>A; p.R198Q; 2:113940011-113940011	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.752A>C; p.K251T; 2:113942253-113942253	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.376A>C; p.T126P; 2:113931340-113931340	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.721G>T; p.E241*; 2:113942222-113942222	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.721G>T; p.E241*; 2:113942222-113942222	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.448G>T; p.A150S; 2:113934294-113934294	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.1234_1235CC>TT; p.P412L; 2:113957432-113957433	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.455C>T; p.S152F; 2:113934301-113934301	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.492C>T; p.T164T; 2:113934338-113934338	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1230C>A; p.H410Q; 2:113957428-113957428	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1191A>C; p.K397N; 2:113957389-113957389	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.331_332insTT; p.L112fs*2; 2:113927450-113927451	lung	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1253C>T; p.S418L; 2:113957451-113957451	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1080A>G; p.P360P; 2:113955625-113955625	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.93C>T; p.I31I; 2:113913220-113913220	skin	malignant_melanoma	Substitution - coding silent
c.932T>C; p.V311A; 2:113951552-113951552	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.123delA; p.V43fs*9; 2:113916906-113916906	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.375T>C; p.Y125Y; 2:113931339-113931339	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.309A>T; p.A103A; 2:113927428-113927428	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.309A>T; p.A103A; 2:113927428-113927428	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.984C>G; p.F328L; 2:113951752-113951752	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1188C>G; p.T396T; 2:113957386-113957386	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.713T>C; p.L238S; 2:113942214-113942214	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1195G>A; p.D399N; 2:113957393-113957393	skin	malignant_melanoma	Substitution - Missense
c.19G>T; p.A7S; 2:113890298-113890298	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1183C>G; p.H395D; 2:113957381-113957381	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.923C>A; p.P308H; 2:113951543-113951543	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.411A>T; p.P137P; 2:113931375-113931375	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.95C>A; p.P32H; 2:113913222-113913222	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.461C>T; p.T154I; 2:113934307-113934307	skin	malignant_melanoma	Substitution - Missense
c.1234C>T; p.P412S; 2:113957432-113957432	skin; nipple	malignant_melanoma	Substitution - Missense
c.582A>G; p.P194P; 2:113940000-113940000	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.265A>C; p.M89L; 2:113927384-113927384	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.68G>T; p.G23V; 2:113913195-113913195	liver	carcinoma	Substitution - Missense
c.927T>A; p.I309I; 2:113951547-113951547	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.808G>A; p.D270N; 2:113942309-113942309	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.777C>T; p.I259I; 2:113942278-113942278	central_nervous_system; brain	glioma	Substitution - coding silent
c.808G>A; p.D270N; 2:113942309-113942309	peritoneum; appendix	other; pseudomyxoma_peritonei	Substitution - Missense

COSMIC somatic mutation [Top]