Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

10055

Name

SAE1

Synonymous

SUMO1 activating enzyme subunit 1;SAE1;SUMO1 activating enzyme subunit 1

Definition

SUMO-1 activating enzyme E1 N subunit|SUMO-1 activating enzyme subunit 1|SUMO-activating enzyme subunit 1|activator of SUMO1|sentrin/SUMO-activating protein AOS1|ubiquitin-like 1-activating enzyme E1A|ubiquitin-like protein SUMO-1 activating enzyme

Position

19q13.32

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.473delT; p.F159fs*11; 19:47152986-47152986

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.473delT; p.F159fs*11; 19:47152986-47152986

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.175G>A; p.G59R; 19:47143570-47143570

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.703C>A; p.R235S; 19:47169893-47169893

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.322G>T; p.V108L; 19:47150313-47150313

 thyroidother; neoplasmSubstitution - Missense

c.727C>T; p.L243F; 19:47169917-47169917

 skinmalignant_melanomaSubstitution - Missense

c.132G>A; p.L44L; 19:47143527-47143527

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.292C>T; p.R98*; 19:47150283-47150283

 oesophaguscarcinoma; adenocarcinomaSubstitution - Nonsense

c.704G>A; p.R235H; 19:47169894-47169894

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.748C>T; p.R250C; 19:47197247-47197247

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.456G>T; p.K152N; 19:47152969-47152969

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.689A>T; p.K230M; 19:47169879-47169879

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.870C>A; p.D290E; 19:47197369-47197369

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.293G>A; p.R98Q; 19:47150284-47150284

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.505C>G; p.L169V; 19:47153018-47153018

 oesophaguscarcinomaSubstitution - Missense

c.813G>C; p.Q271H; 19:47197312-47197312

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.387G>T; p.V129V; 19:47152900-47152900

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.515A>G; p.H172R; 19:47153028-47153028

 skinmalignant_melanomaSubstitution - Missense

c.172G>A; p.A58T; 19:47143567-47143567

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.894G>T; p.E298D; 19:47203686-47203686

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.358G>A; p.E120K; 19:47150349-47150349

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.132G>T; p.L44F; 19:47143527-47143527

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.656C>T; p.A219V; 19:47169846-47169846

 breastcarcinomaSubstitution - Missense

c.817C>T; p.R273*; 19:47197316-47197316

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.445A>T; p.N149Y; 19:47152958-47152958

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.719A>T; p.Y240F; 19:47169909-47169909

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.794A>T; p.D265V; 19:47197293-47197293

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.163C>T; p.L55F; 19:47143558-47143558

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.163C>T; p.L55F; 19:47143558-47143558

 skinmalignant_melanomaSubstitution - Missense

c.148G>A; p.E50K; 19:47143543-47143543

 skinmalignant_melanomaSubstitution - Missense

c.917T>C; p.V306A; 19:47203709-47203709

 skinmalignant_melanomaSubstitution - Missense

c.981_983delCTT; p.F331delF; 19:47209191-47209193

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.37G>C; p.E13Q; 19:47130967-47130967

 breastcarcinomaSubstitution - Missense

c.576C>T; p.P192P; 19:47155162-47155162

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.576C>T; p.P192P; 19:47155162-47155162

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.769C>T; p.P257S; 19:47197268-47197268

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.915G>T; p.V305V; 19:47203707-47203707

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.265C>T; p.R89*; 19:47150256-47150256

 breastcarcinomaSubstitution - Nonsense

c.642C>T; p.C214C; 19:47169832-47169832

 skinmalignant_melanomaSubstitution - coding silent

c.93G>T; p.Q31H; 19:47131023-47131023

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.833A>G; p.D278G; 19:47197332-47197332

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.786T>C; p.Y262Y; 19:47197285-47197285

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.285T>C; p.S95S; 19:47150276-47150276

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemiaSubstitution - coding silent

c.884G>A; p.C295Y; 19:47203676-47203676

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.103C>T; p.R35W; 19:47143498-47143498

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.875T>C; p.V292A; 19:47197374-47197374

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.952C>T; p.L318L; 19:47209162-47209162

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.890C>T; p.S297F; 19:47203682-47203682

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.911C>T; p.A304V; 19:47203703-47203703

 breastcarcinomaSubstitution - Missense

c.1001T>C; p.M334T; 19:47209211-47209211

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.455A>C; p.K152T; 19:47152968-47152968

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.949-1G>T; p.?; 19:47209158-47209158

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.54G>A; p.Q18Q; 19:47130984-47130984

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.459C>A; p.F153L; 19:47152972-47152972

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense