Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

100506658

Name

OCLN

Synonymous

occludin;OCLN;occludin

Definition

phosphatase 1, regulatory subunit 115|tight junction protein occludin

Position

5q13.1

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.587G>T; p.G196V; 5:69509677-69509677

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.257C>T; p.T86M; 5:69509347-69509347

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.257C>T; p.T86M; 5:69509347-69509347

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.38delG; p.R13fs*52; 5:69504282-69504282

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.462G>A; p.V154V; 5:69509552-69509552

 skinmalignant_melanomaSubstitution - coding silent

c.1556G>A; p.R519K; 5:69553658-69553658

 skinmalignant_melanomaSubstitution - Missense

c.143C>T; p.P48L; 5:69509233-69509233

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.611C>G; p.S204C; 5:69509701-69509701

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.649A>G; p.N217D; 5:69509739-69509739

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.454G>T; p.A152S; 5:69509544-69509544

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.160C>G; p.H54D; 5:69509250-69509250

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.25C>T; p.P9S; 5:69504269-69504269

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.211C>T; p.L71F; 5:69509301-69509301

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.880G>A; p.V294I; 5:69514098-69514098

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.803G>A; p.R268Q; 5:69514021-69514021

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.323G>A; p.G108E; 5:69509413-69509413

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1512G>C; p.K504N; 5:69553614-69553614

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.892-9delT; p.?; 5:69534685-69534685

 stomachadenocarcinomaUnknown

c.344G>A; p.G115E; 5:69509434-69509434

 skinmalignant_melanomaSubstitution - Missense

c.10A>T; p.R4W; 5:69504254-69504254

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1004G>A; p.R335Q; 5:69534806-69534806

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.754A>G; p.M252V; 5:69513972-69513972

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.182C>A; p.P61H; 5:69509272-69509272

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.365A>G; p.Y122C; 5:69509455-69509455

 livercarcinomaSubstitution - Missense

c.365A>G; p.Y122C; 5:69509455-69509455

 livercarcinomaSubstitution - Missense

c.795G>A; p.V265V; 5:69514013-69514013

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.8C>G; p.S3C; 5:69504252-69504252

 breastcarcinomaSubstitution - Missense

c.384C>T; p.Y128Y; 5:69509474-69509474

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.384C>T; p.Y128Y; 5:69509474-69509474

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.197G>A; p.R66Q; 5:69509287-69509287

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.81C>T; p.D27D; 5:69509171-69509171

 prostatecarcinomaSubstitution - coding silent

c.304G>A; p.V102I; 5:69509394-69509394

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.62A>G; p.H21R; 5:69509152-69509152

 livercarcinomaSubstitution - Missense

c.62A>G; p.H21R; 5:69509152-69509152

 livercarcinomaSubstitution - Missense

c.528A>C; p.I176I; 5:69509618-69509618

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.559T>C; p.F187L; 5:69509649-69509649

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.127G>A; p.A43T; 5:69509217-69509217

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.382T>C; p.Y128H; 5:69509472-69509472

 skin; trunkmalignant_melanoma; nodularSubstitution - Missense

c.815A>G; p.D272G; 5:69514033-69514033

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.849_850GG>AA; p.E284K; 5:69514067-69514068

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1115G>A; p.G372D; 5:69544981-69544981

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.891G>T; p.W297C; 5:69514109-69514109

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.289C>G; p.L97V; 5:69509379-69509379

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.437C>T; p.A146V; 5:69509527-69509527

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.485G>T; p.R162I; 5:69509575-69509575

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.314C>T; p.P105L; 5:69509404-69509404

 skinmalignant_melanomaSubstitution - Missense

c.420C>T; p.F140F; 5:69509510-69509510

 skinmalignant_melanomaSubstitution - coding silent

c.1243G>A; p.D415N; 5:69545109-69545109

 breastcarcinomaSubstitution - Missense

c.614G>A; p.G205E; 5:69509704-69509704

 skinmalignant_melanomaSubstitution - Missense

c.617C>A; p.S206Y; 5:69509707-69509707

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.436G>T; p.A146S; 5:69509526-69509526

 livercarcinomaSubstitution - Missense

c.436G>T; p.A146S; 5:69509526-69509526

 livercarcinomaSubstitution - Missense

c.647G>T; p.C216F; 5:69509737-69509737

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Missense

c.519A>T; p.L173F; 5:69509609-69509609

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.69A>G; p.A23A; 5:69509159-69509159

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - coding silent

c.802C>T; p.R268*; 5:69514020-69514020

 skinmalignant_melanomaSubstitution - Nonsense

c.802C>T; p.R268*; 5:69514020-69514020

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.802C>T; p.R268*; 5:69514020-69514020

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Nonsense

c.241G>T; p.A81S; 5:69509331-69509331

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.241G>T; p.A81S; 5:69509331-69509331

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.625G>A; p.G209S; 5:69509715-69509715

 thyroidcarcinomaSubstitution - Missense

c.46G>A; p.E16K; 5:69504290-69504290

 skinmalignant_melanomaSubstitution - Missense

c.685G>T; p.V229L; 5:69509775-69509775

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1218C>G; p.G406G; 5:69545084-69545084

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.890G>T; p.W297L; 5:69514108-69514108

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.208A>G; p.M70V; 5:69509298-69509298

 livercarcinomaSubstitution - Missense

c.208A>G; p.M70V; 5:69509298-69509298

 livercarcinomaSubstitution - Missense

c.208A>G; p.M70V; 5:69509298-69509298

 livercarcinomaSubstitution - Missense

c.208A>G; p.M70V; 5:69509298-69509298

 livercarcinomaSubstitution - Missense

c.119C>G; p.S40C; 5:69509209-69509209

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.543C>T; p.I181I; 5:69509633-69509633

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent