Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

10011

Name

SRA1

Synonymous

steroid receptor RNA activator 1;SRA1;steroid receptor RNA activator 1

Definition

steroid receptor RNA activator 1 (complexes with NCOA1)|steroid receptor RNA activator protein|steroid receptor coactivator

Position

5q31.3

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.523G>A; p.A175T; 5:140550888-140550888

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.385A>G; p.T129A; 5:140551987-140551987

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.328_329insAC; p.V110fs*2; 5:140552043-140552044

 breastcarcinomaInsertion - Frameshift

c.328_329insAC; p.V110fs*2; 5:140552043-140552044

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.328_329insAC; p.V110fs*2; 5:140552043-140552044

 livercarcinomaInsertion - Frameshift

c.328_329insAC; p.V110fs*2; 5:140552043-140552044

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; hairy_cell_leukaemiaInsertion - Frameshift

c.329_330insGAC; p.V110_M111insT; 5:140552042-140552043

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.329_330insGAC; p.V110_M111insT; 5:140552042-140552043

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.329_330insGAC; p.V110_M111insT; 5:140552042-140552043

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.328_329insGAC; p.V110>GL; 5:140552043-140552044

 central_nervous_system; brainglioma; astrocytoma_Grade_IIComplex - insertion inframe

c.329_330insGAC; p.V110_M111insT; 5:140552042-140552043

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.329_330insGAC; p.V110_M111insT; 5:140552042-140552043

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.329_330insGAC; p.V110_M111insT; 5:140552042-140552043

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.329_330insGAC; p.V110_M111insT; 5:140552042-140552043

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.329_330insGAC; p.V110_M111insT; 5:140552042-140552043

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.329_330insGAC; p.V110_M111insT; 5:140552042-140552043

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.329_330insGAC; p.V110_M111insT; 5:140552042-140552043

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.329_330insGAC; p.V110_M111insT; 5:140552042-140552043

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.14C>A; p.P5H; 5:140557475-140557475

 oesophaguscarcinomaSubstitution - Missense

c.21C>T; p.G7G; 5:140557468-140557468

 ovaryother; neoplasmSubstitution - coding silent

c.510C>T; p.S170S; 5:140550901-140550901

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.325G>A; p.A109T; 5:140552047-140552047

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.662C>T; p.A221V; 5:140550749-140550749

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.466C>A; p.P156T; 5:140551094-140551094

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.22C>T; p.Q8*; 5:140557467-140557467

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.638C>T; p.A213V; 5:140550773-140550773

 prostatecarcinomaSubstitution - Missense

c.248A>G; p.K83R; 5:140552124-140552124

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.328_329insAAC; p.V110>EL; 5:140552043-140552044

 breastcarcinomaComplex - insertion inframe

c.419G>T; p.R140L; 5:140551141-140551141

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.568G>A; p.E190K; 5:140550843-140550843

 breastcarcinomaSubstitution - Missense

c.329_330insAC; p.M111fs*6; 5:140552042-140552043

 large_intestinecarcinoma; adenocarcinomaInsertion - Frameshift

c.329_330insAC; p.M111fs*6; 5:140552042-140552043

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - Frameshift

c.188-8C>T; p.?; 5:140552192-140552192

 lungcarcinoma; squamous_cell_carcinomaUnknown

c.654A>G; p.K218K; 5:140550757-140550757

 livercarcinomaSubstitution - coding silent

c.474G>T; p.K158N; 5:140551086-140551086

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.152A>G; p.K51R; 5:140557182-140557182

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.359A>C; p.Q120P; 5:140552013-140552013

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.417A>G; p.R139R; 5:140551143-140551143

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.651G>T; p.E217D; 5:140550760-140550760

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.328_329insC; p.V110fs*26; 5:140552043-140552044

 large_intestinecarcinoma; adenocarcinomaInsertion - Frameshift

c.328_329insC; p.V110fs*26; 5:140552043-140552044

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - Frameshift

c.328_329insC; p.V110fs*26; 5:140552043-140552044

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaInsertion - Frameshift

c.329T>A; p.V110E; 5:140552043-140552043

 pancreaspancreatic_intraepithelial_neoplasia_(PanIN)Substitution - Missense

c.391-6_391-5delTC; p.?; 5:140551174-140551175

 lungcarcinoma; adenocarcinomaUnknown

c.640G>A; p.A214T; 5:140550771-140550771

 bone; iliumEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.9C>T; p.R3R; 5:140557480-140557480

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.223A>G; p.M75V; 5:140552149-140552149

 livercarcinomaSubstitution - Missense

c.61+9A>T; p.?; 5:140557419-140557419

 livercarcinomaUnknown

c.61+9A>T; p.?; 5:140557419-140557419

 livercarcinomaUnknown

c.159C>A; p.V53V; 5:140557175-140557175

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.159C>A; p.V53V; 5:140557175-140557175

 thyroidother; neoplasmSubstitution - coding silent

c.329T>G; p.V110G; 5:140552043-140552043

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.420C>T; p.R140R; 5:140551140-140551140

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.328G>C; p.V110L; 5:140552044-140552044

 large_intestine; rectumadenomaSubstitution - Missense

c.328G>C; p.V110L; 5:140552044-140552044

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.328G>C; p.V110L; 5:140552044-140552044

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.328G>C; p.V110L; 5:140552044-140552044

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.328G>C; p.V110L; 5:140552044-140552044

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.328G>C; p.V110L; 5:140552044-140552044

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.328G>C; p.V110L; 5:140552044-140552044

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.328G>C; p.V110L; 5:140552044-140552044

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.328G>C; p.V110L; 5:140552044-140552044

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.328G>C; p.V110L; 5:140552044-140552044

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.328G>C; p.V110L; 5:140552044-140552044

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.329_330delTG; p.V110fs*25; 5:140552042-140552043

 central_nervous_system; brainglioma; astrocytoma_Grade_IVDeletion - Frameshift

c.328G>C; p.V110L; 5:140552044-140552044

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.328G>C; p.V110L; 5:140552044-140552044

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.328G>C; p.V110L; 5:140552044-140552044

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.176G>C; p.G59A; 5:140557158-140557158

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.326_327insT; p.V110fs*26; 5:140552045-140552046

 NSmalignant_melanomaInsertion - Frameshift

c.641C>T; p.A214V; 5:140550770-140550770

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.638C>A; p.A213E; 5:140550773-140550773

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.471A>G; p.V157V; 5:140551089-140551089

 pancreascarcinoid-endocrine_tumourSubstitution - coding silent