| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10419 |
Name | PRMT5 |
Synonymous | protein arginine methyltransferase 5;PRMT5;protein arginine methyltransferase 5 |
Definition | 72 kDa ICln-binding protein|HMT1 hnRNP methyltransferase-like 5|SKB1 homolog|histone-arginine N-methyltransferase PRMT5|jak-binding protein 1|protein arginine N-methyltransferase 5|shk1 kinase-binding protein 1 homolog |
Position | 14q11.2 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
CLNS1A | REACTOME; |
in same component |
TTC5 | NCI_NATURE; |
in same component |
WDR77 | NCI_NATURE; |
in same component |
WDR77 | REACTOME; |
interacts with |
ACTB | MINT; |
interacts with |
ATP1A1 | MINT; |
interacts with |
ATP5C1 | MINT; |
interacts with |
BTRC | MINT; |
interacts with |
C1QBP | HPRD; |
interacts with |
C3orf26 | MINT; |
interacts with |
CAPN1 | HPRD; |
interacts with |
CBX1 | HPRD; |
interacts with |
CBX5 | HPRD; |
interacts with |
CBX5 | MINT; |
interacts with |
CCND1 | BIOGRID; |
interacts with |
CDK4 | BIOGRID; |
interacts with |
CHAF1A | MINT; |
interacts with |
CHAF1B | MINT; |
interacts with |
CLNS1A | BIOGRID; |
interacts with |
CLNS1A | HPRD; |
interacts with |
COPA | MINT; |
interacts with |
COPR5 | MINT; |
interacts with |
CTDP1 | BIOGRID; |
interacts with |
CTDP1 | HPRD; |
interacts with |
CTDP1 | MINT; |
interacts with |
CTNNBL1 | BIOGRID; |
interacts with |
DDOST | MINT; |
interacts with |
DDX20 | HPRD; |
interacts with |
DDX21 | HPRD; |
interacts with |
DDX39A | MINT; |
interacts with |
DEK | HPRD; |
interacts with |
DHCR7 | MINT; |
interacts with |
DHX15 | MINT; |
interacts with |
DHX30 | MINT; |
interacts with |
DHX36 | MINT; |
interacts with |
DHX9 | MINT; |
interacts with |
DICER1 | MINT; |
interacts with |
DNAJA2 | MINT; |
interacts with |
DNMT3A | BIOGRID; |
interacts with |
EBNA1BP2 | MINT; |
interacts with |
EEF1A1 | MINT; |
interacts with |
EIF2B4 | MINT; |
interacts with |
EIF2C1 | MINT; |
interacts with |
EIF2C2 | MINT; |
interacts with |
EIF4A3 | MINT; |
interacts with |
EPRS | MINT; |
interacts with |
FBL | BIOGRID; |
interacts with |
FBL | HPRD; |
interacts with |
FBL | MINT; |
interacts with |
FBXL13 | MINT; |
interacts with |
FXR1 | MINT; |
interacts with |
GEMIN4 | MINT; |
interacts with |
GNL3 | MINT; |
interacts with |
GSK3B | MINT; |
interacts with |
H2AFX | HPRD; |
interacts with |
H2AFY | HPRD; |
interacts with |
HEMGN | MINT; |
interacts with |
HERC5 | MINT; |
interacts with |
HIST1H1A | HPRD; |
interacts with |
HIST1H2AB | MINT; |
interacts with |
HIST1H2BC | HPRD; |
interacts with |
HIST2H2AC | BIOGRID; |
interacts with |
HNRNPC | MINT; |
interacts with |
HNRNPF | MINT; |
interacts with |
HNRNPH2 | MINT; |
interacts with |
HNRNPUL1 | MINT; |
interacts with |
HNRNPU | MINT; |
interacts with |
HP1BP3 | HPRD; |
interacts with |
HRNR | MINT; |
interacts with |
HSP90AA1 | BIOGRID; |
interacts with |
HSP90AB1 | MINT; |
interacts with |
HSPA6 | HPRD; |
interacts with |
HSPD1 | MINT; |
interacts with |
IGF2BP1 | MINT; |
interacts with |
ILF2 | MINT; |
interacts with |
IMMT | MINT; |
interacts with |
IPO9 | MINT; |
interacts with |
JAK1 | BIOGRID; |
interacts with |
JAK1 | HPRD; |
interacts with |
JAK2 | BIOGRID; |
interacts with |
JAK2 | HPRD; |
interacts with |
JAK2 | INTACT; |
interacts with |
JAK3 | BIOGRID; |
interacts with |
JAK3 | HPRD; |
interacts with |
JUB | BIOGRID; |
interacts with |
KDM1A | MINT; |
interacts with |
KHDRBS2 | BIOGRID; |
interacts with |
KRR1 | MINT; |
interacts with |
LRRC59 | MINT; |
interacts with |
LSM11 | BIOGRID; |
interacts with |
LYAR | MINT; |
interacts with |
MATR3 | MINT; |
interacts with |
MBD2 | BIOGRID; |
interacts with |
MBP | BIOGRID; |
interacts with |
MBP | HPRD; |
interacts with |
MEF2D | BIOGRID; |
interacts with |
MRPS15 | MINT; |
interacts with |
MRPS16 | MINT; |
interacts with |
MRPS22 | MINT; |
interacts with |
MRPS23 | MINT; |
interacts with |
MRPS27 | MINT; |
interacts with |
MRPS5 | MINT; |
interacts with |
MYOD1 | BIOGRID; |
interacts with |
MYOG | BIOGRID; |
interacts with |
MYSM1 | BIOGRID; |
interacts with |
NCL | BIOGRID; |
interacts with |
NFE4 | BIOGRID; |
interacts with |
OLA1 | BIOGRID; |
interacts with |
OLA1 | HPRD; |
interacts with |
PABPC1 | MINT; |
interacts with |
PARP1 | HPRD; |
interacts with |
PAXIP1 | BIOGRID; |
interacts with |
PDCD1 | MINT; |
interacts with |
PHB2 | MINT; |
interacts with |
PHB | MINT; |
interacts with |
PHF5A | MINT; |
interacts with |
PHYHIP | BIOGRID; |
interacts with |
PHYHIP | HPRD; |
interacts with |
PIAS4 | MINT; |
interacts with |
POGZ | MINT; |
interacts with |
PRDM1 | BIOGRID; |
interacts with |
PRMT1 | HPRD; |
interacts with |
PTCD3 | MINT; |
interacts with |
RAN | HPRD; |
interacts with |
RBM10 | MINT; |
interacts with |
RBM4 | MINT; |
interacts with |
RCC1 | HPRD; |
interacts with |
RIF1 | MINT; |
interacts with |
RNF149 | MINT; |
interacts with |
RPL10 | MINT; |
interacts with |
RPL12 | MINT; |
interacts with |
RPL13A | MINT; |
interacts with |
RPL13 | MINT; |
interacts with |
RPL14 | MINT; |
interacts with |
Rpl17 | MINT; |
interacts with |
RPL17 | MINT; |
interacts with |
RPL18A | MINT; |
interacts with |
RPL18 | MINT; |
interacts with |
RPL21 | MINT; |
interacts with |
RPL27A | MINT; |
interacts with |
RPL28 | MINT; |
interacts with |
RPL29 | MINT; |
interacts with |
Rpl34 | MINT; |
interacts with |
RPL35A | MINT; |
interacts with |
RPL35 | MINT; |
interacts with |
RPL3 | MINT; |
interacts with |
RPL4 | MINT; |
interacts with |
RPL6 | MINT; |
interacts with |
RPL7 | MINT; |
interacts with |
RPLP0 | MINT; |
interacts with |
RPS27L | MINT; |
interacts with |
RPS2 | MINT; |
interacts with |
RPS3 | MINT; |
interacts with |
RPS5 | MINT; |
interacts with |
RPS9 | MINT; |
interacts with |
RUVBL2 | MINT; |
interacts with |
SART3 | MINT; |
interacts with |
SF3B14 | MINT; |
interacts with |
SF3B1 | MINT; |
interacts with |
SF3B2 | MINT; |
interacts with |
SF3B3 | MINT; |
interacts with |
SIN3A | BIOGRID; |
interacts with |
SIP1 | HPRD; |
interacts with |
SIRT1 | MINT; |
interacts with |
SKI | BIOGRID; |
interacts with |
SLC25A13 | MINT; |
interacts with |
SLC25A3 | MINT; |
interacts with |
SLC25A5 | MINT; |
interacts with |
SLC25A6 | MINT; |
interacts with |
SLC4A5 | MINT; |
interacts with |
SMARCA2 | BIOGRID; |
interacts with |
SMARCA4 | BIOGRID; |
interacts with |
SMARCA4 | MINT; |
interacts with |
SMARCB1 | BIOGRID; |
interacts with |
SMARCC1 | BIOGRID; |
interacts with |
SMARCE1 | BIOGRID; |
interacts with |
SMN1 | HPRD; |
interacts with |
SNAI1 | MINT; |
interacts with |
SNRPB | HPRD; |
interacts with |
SSR1 | MINT; |
interacts with |
SSTR1 | HPRD; |
interacts with |
STOML2 | MINT; |
interacts with |
SUPT5H | BIOGRID; |
interacts with |
SUPT5H | HPRD; |
interacts with |
SUPT5H | MINT; |
interacts with |
SUPT6H | MINT; |
interacts with |
SYNCRIP | MINT; |
interacts with |
SYNE1 | MINT; |
interacts with |
TARBP2 | MINT; |
interacts with |
TERF1 | BIOGRID; |
interacts with |
TERF2 | BIOGRID; |
interacts with |
TMEM33 | MINT; |
interacts with |
TOP1 | HPRD; |
interacts with |
TRIM28 | MINT; |
interacts with |
TUBA1A | HPRD; |
interacts with |
TUBA1A | MINT; |
interacts with |
TUBB | HPRD; |
interacts with |
TUBB | MINT; |
interacts with |
TYK2 | BIOGRID; |
interacts with |
TYK2 | HPRD; |
interacts with |
WDR77 | BIOGRID; |
interacts with |
WDR77 | HPRD; |
interacts with |
WDR77 | MINT; |
interacts with |
XRCC5 | HPRD; |
interacts with |
XRCC6 | HPRD; |
interacts with |
XRCC6 | MINT; |
interacts with |
Ybx1 | MINT; |
interacts with |
YBX1 | MINT; |
interacts with |
YWHAB | MINT; |
interacts with |
YWHAG | HPRD; |
interacts with |
YWHAQ | HPRD; |
interacts with |
YWHAQ | MINT; |
interacts with |
YWHAZ | MINT; |
interacts with |
ZNF224 | BIOGRID; |
interacts with |
ZNF326 | MINT; |
Metabolic Interaction [Top] | ||
There is no record for PRMT5 | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
CHD3 | NCI_NATURE; |
reacts with |
CHD4 | NCI_NATURE; |
reacts with |
GATAD2A | NCI_NATURE; |
reacts with |
GATAD2B | NCI_NATURE; |
reacts with |
HDAC1 | NCI_NATURE; |
reacts with |
HDAC2 | NCI_NATURE; |
reacts with |
MBD2 | NCI_NATURE; |
reacts with |
MTA2 | NCI_NATURE; |
reacts with |
PRMT5 | NCI_NATURE; |
reacts with |
RBBP4 | NCI_NATURE; |
reacts with |
RBBP7 | NCI_NATURE; |
reacts with |
TTC5 | NCI_NATURE; |