| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 9922 |
Name | IQSEC1 |
Synonym | ARF-GEP100|ARFGEP100|BRAG2|GEP100;IQ motif and Sec7 domain 1;IQSEC1;IQ motif and Sec7 domain 1 |
Definition | ADP-ribosylation factors guanine nucleotide-exchange protein 100|ADP-ribosylation factors guanine nucleotide-exchange protein 2|IQ motif and SEC7 domain-containing protein 1|brefeldin A-resistant ARF-GEF2|brefeldin-resistant Arf-GEF 2 protein |
Position | 3p25.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Arf6 signaling events;PID Curated;200060 |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Disease | Cancer;FunDO |
External Links | |
Links to Entrez Gene | 9922 |
Links to all GeneRIF Items | 9922 |
Links to iHOP | 9922 |
Sequence Information | |
Nucleotide Sequence | >9922 : length: 7599 GGGCCAGCCCCTGGGCTCCGGCAGCTGAGCTTTTCCTCACCGGCGGACGCCCCTCACCCA TCCCGCCCTGAGTGACTCACTGCTCCCCTGGCCTGCAGCCACTGCTGTCTCCTGGCAGGA GGCAGGCGCAAGGTTGTGCAGAAGCCACAGGGTCTAGTGTGTGAGGGCCGCTTGGCCAGG AGGGTCTGGAGCAGCTAGACAGGACCAGGGCACAGAGGCTGGCCGGTGGATAGTGGGGCC TGTGGCTCAGCCCTGCAGTGGCCTGTGGCAGCCAGTGCCTCCTCTTTTCCCTAACTTTGG GGGCTTTTCTTTCTTCTTCCTACCATGAAGAAGGAAGGGACCTGAAAATCCGTGAAGAGA GCCGTTCCCTGGCCAGGAGGAGACTCTGGGTGGTGGGGCAGTGGTGGTGGGCCCCTTGGC CACTCGCTCCTCCACCGAGCCAGGCATGAAGGGGTATGGCAGTGCCGTGTGGAGCCTTAT GTGGAAGTACTGCATCTCTGTGAGGACACTCAGCGTCGAGGGCGAGGCCCCCAGCAGTGA GACTGGCACATCCCTGGACAGCCCCTCAGCCTACCCCCAGGGCCCCTTGGTGCCCGGTTC CAGCCTGAGCCCGGATCACTACGAGCACACGTCAGTGGGAGCCTATGGGCTGTACTCGGG GCCGCCGGGGCAACAGCAGCGCACGCGGAGGCCCAAGCTGCAGCACTCGACCTCCATCCT GCGCAAGCAGGCTGAGGAGGAGGCCATCAAGCGCTCACGCTCACTCTCCGAGAGCTATGA GCTCTCCTCGGACCTGCAGGACAAGCAGGTGGAGATGCTAGAACGAAAGTATGGGGGGCG CCTGGTAACCCGCCATGCGGCCCGCACCATCCAGACGGCGTTTCGCCAGTACCAGATGAA CAAGAACTTCGAGCGCTTGCGCAGCTCCATGTCAGAGAACCGCATGTCACGCCGGATTGT GCTGTCCAACATGAGGATGCAGTTCTCCTTTGAGGGGCCTGAGAAAGTGCACAGCTCCTA CTTCGAGGGGAAGCAGGTCTCAGTGACTAACGACGGCTCCCAGCTGGGAGCCCTGGTGTC CCCTGAGTGTGGTGACCTCAGCGAGCCCACCACCCTCAAGTCTCCGGCCCCCTCCAGTGA CTTTGCGGACGCCATCACCGAGCTGGAGGACGCCTTCTCTAGGCAAGTGAAATCACTGGC CGAGTCCATCGACGATGCCCTCAACTGCCGCAGCCTGCACACTGAGGAGGCACCGGCCCT GGATGCGGCGCGGGCCCGGGACACCGAACCCCAGACAGCCCTGCACGGCATGGACCACCG CAAACTGGACGAGATGACGGCCTCGTACAGTGATGTCACCCTGTACATCGATGAGGAGGA GCTGTCGCCCCCTCTGCCCCTCTCGCAGGCAGGGGACCGGCCGTCCAGCACCGAGTCGGA CCTGCGGCTACGGGCTGGGGGCGCAGCCCCAGACTACTGGGCCCTGGCCCACAAAGAGGA CAAGGCTGACACGGACACGAGCTGCCGGAGCACGCCGTCGCTGGAGCGGCAGGAGCAGCG GCTGCGGGTGGAGCATCTGCCGCTGCTCACCATCGAGCCACCCAGCGACAGCTCTGTGGA CCTTAGTGACCGCTCGGAGCGGGGGTCACTCAAGAGGCAGAGTGCTTACGAGCGCAGCCT TGGCGGGCAGCAGGGCAGTCCCAAGCATGGTCCCCACAGCGGCGCCCCCAAGAGCCTCCC CCGGGAGGAGCCTGAGTTGCGGCCCCGGCCCCCCAGGCCCCTGGACAGCCACTTGGCCAT CAATGGCTCAGCCAACCGGCAGAGCAAGTCTGAGTCGGACTACTCAGACGGTGACAATGA CAGCATCAACAGCACGTCCAACTCCAACGATACCATCAACTGCAGCTCCGAGTCATCGTC CCGTGACAGCCTGCGGGAGCAGACGCTCAGCAAGCAGACCTACCACAAGGAGGCCCGCAA CAGCTGGGACTCGCCTGCCTTTAGCAACGATGTCATCCGCAAGAGGCACTACCGCATCGG CCTGAACCTCTTCAACAAGAAGCCTGAGAAGGGAGTCCAGTACCTCATCGAGCGTGGCTT TGTGCCCGACACGCCCGTCGGGGTGGCCCACTTCCTGCTGCAGCGCAAGGGCCTCAGCCG GCAGATGATCGGCGAGTTCCTGGGCAACCGGCAGAAGCAGTTCAACCGTGACGTGCTCGA CTGCGTCGTGGACGAGATGGACTTCTCTACCATGGAGCTGGATGAGGCCCTCAGGAAATT CCAGGCGCACATCCGTGTCCAAGGGGAGGCTCAGAAAGTGGAGCGGCTCATAGAGGCGTT CAGCCAGCGCTACTGCATCTGCAACCCTGGGGTGGTGCGGCAATTCCGGAACCCAGACAC CATTTTCATCCTGGCCTTCGCCATCATCCTGCTGAACACCGACATGTACAGCCCCAATGT CAAGCCCGAGCGGAAAATGAAGCTAGAGGACTTCATCAAGAACCTCCGAGGTGTGGACGA TGGTGAGGACATTCCCCGTGAGATGCTGATGGGGATCTATGAACGGATCCGTAAGCGAGA GCTAAAGACCAATGAGGACCATGTGTCCCAGGTGCAGAAGGTGGAGAAGCTCATTGTGGG GAAAAAGCCGATCGGATCCCTGCATCCCGGGCTCGGCTGTGTGCTCTCTCTGCCCCACCG TCGGTTGGTCTGCTACTGCCGGCTCTTTGAGGTTCCAGACCCAAACAAGCCCCAGAAACT CGGACTACACCAGCGAGAAATCTTCCTGTTCAACGACCTCCTGGTGGTCACCAAGATCTT CCAGAAGAAGAAGAACTCGGTGACGTACAGCTTCCGACAGTCCTTCTCCTTGTACGGCAT GCAGGTCCTGCTCTTCGAGAACCAGTACTACCCCAATGGCATCCGGCTCACCTCGTCTGT CCCCGGAGCAGATATCAAAGTGTTAATAAACTTCAACGCCCCCAACCCTCAAGACCGGAA GAAATTCACCGATGACCTGCGGGAGTCCATTGCGGAAGTCCAAGAGATGGAGAAGCACAG GATAGAGTCGGAGCTCGAGAAGCAGAAAGGCGTCGTGCGGCCCAGCATGTCCCAGTGCTC TAGCCTCAAAAAGGAGTCGGGCAACGGAACACTGAGCCGGGCCTGCCTGGACGACAGCTA TGCCAGCGGTGAGGGCCTCAAGCGCAGCGCCCTCAGCAGCTCCCTGCGGGACCTCTCGGA AGCCGGGAAGCGAGGGCGTCGCAGCAGTGCGGGATCGCTAGAGAGCAATGTGGAAGGGTC CATCATTAGCAGTCCTCACATGCGCCGGAGAGCTACATCAACACGAGAGTGTCCATCTCG CCCACACCAGACTATGCCCAACTCATCTTCCCTCCTGGGCTCCTTATTCGGGAGCAAGAG AGGGAAGCCCCCTCCCCAGGCCCACCTGCCCTCAGCCCCAGCCCTGCCACCCCCCCACCC ACCGGTGGTCCTGCCTCACTTGCAGCACTCTGTGGCTGGCCACCACCTGGGGCCCCCAGA GGGGCTGCCGCAGGCCGCCATGCACGGGCATCACACCCAGTACTGCCACATGCAGAACCC TCCCCCGTACCACCATCACCACCACCACCACCCACCCCAGCACATCCAGCACGCACACCA GTACCACCACGGCCCCCATGGGGGCCACCCAGCCTACGGGGCCCATGCCCACGGCCACCC GCCGCTGCCCTCGGCCCACGTGGGGCACACAGTGCACCACCATGGGCAGCCCCCTGCCCC GCCGCCCCCCACCAGCAGCAAGGCCAAACCCAGCGGCATCAGCACAATTGTGTAGACAGC CTGGGTAGGGGTCCCAGGCTCCCTGAAACACCTGCACACCACACAGGGCACGCCCGGGGG TCGCCAGCCGCACACCAAACCCGGGGCACTTCTGTTGCCATCTCTCCCCTCTGCCCCTCA CGGCCCAACCGGAGCCCCAGGAGCCCACAGGGCTGGTGTTGTGTGGAACAAAGGCCCAGA TTTCATTTCTTGTTGGCACCCTGGGCTCTGCTCACCTCAGTCTGAGGGATGGGTGGGCCT CAGACACCATCAGCCTTGAAACGGTGAGCCAGCCAAGTAGTGTTGAACTGCCTCCCCCAC TCCAGCTCTCAGCTCCCTGTGCCCTAATGTACATGCATATGAAAACCCAACCTAGAAAAC GAAGAAATGAGATACAAAAACAGACAAAACAAACCCCAAAACTTGCTGCATTATTGCTCT TTTATTGACAATGGGCAAAAAAATAAGTAGACCTGATATGGTTGATGAAAATACGTAAGT AAACTTTATATAAATATATAAATATATAAATATATATATATATATACTGTATAGGTAGTA CTTGTGTGTGAAAGGCAGGCGTTTCAGTCCACATTAGCAATACCCACCTTACAAGGAGCT CCACTTACCTAATAGGAAGACAGTACCTTAGCTGGGTGTGTGAGACAATAGACCAAACCC TAAATGCTAGGAACAAATTCAGATACTTCATATTTTCATACAAAGAAGTCCCTCTAGGAC TGGCTAAAATCTTTACACAATCATTACTAACTGTGCCAAGTAACATAGCATCTAACTGTT TAAAAAGTCCAGTATTGCTTTGTATAAATCCTTATTTTATTAACAGAATACTATCATAAA TAGTATTATAATGCTGTTATTTCAGGTAAGCAAATAGCTAAACTGCAGTACACTCTACAG TAGCAACTCAGGACAGCTGGTTACAAGCTGGTTGTCTTAGGACATTGGTTACACGGATTC TTAGACACTTTAATGGCTGCGATAACTGTGACTCTCCATGATCCATGTTTCTTTTATGCG CATATGATTTGACGCACACTCATTCAGAGTCCTCCGAGAGGGGCACCCATACACGGCAGA AGTGTTCATCTCCAACATGAAAGTGACCAGCTCTCATCCTCGTCTCCCCAACACCATAAC GTCCTCATCCCGCCTCCAACCCACACCAGGCCGAAGCCCTCAGAGAGTGTTTTCATCAGG AACCACTCTCGAACCTGAAGGTTGACTTTAGCGTTTAGCAACCCAGGGCGGTGTGTGTGT TTCCCGTTTTGTTTTCTGAGTGGTAGCAGTGATCACCGTAATTCCATGTAGCCATGTGCT AGCAGAACCCCTGTGTCCTCACCGTGGCCCGTGTGACCCCAGCCGACGAGTGCCCGGCGG AGCCCCCGCTGCCTTCCCATGGTCCAGTGAGCTGCCAGGGCATCACATGACTCTCAGCTG TGCTCTTGTCGCTTCTGTGTTGTGGTGACACCATGCGCTCCCCAGGGCCAGACCTGCACG CGGCAGGTCTGTGCCCGAGTCACCCACGGGCCATACTTTGTAGTTTCAGCCTTTCGAGCC ACTGCAGCCGTCAGTGCTGTGCTCCTAAGCCATGGGACCCGAGGACTGCCCCCCGGCGCC TGCCCAGGCGGAGGCCCTTTCAGAAAGGGCGAAGCTCACGCCTGACTCTGCGGGCCGCGG GGCCGCGTTCCCAGTGGACAGCGTGGTGAGCCGTGGCCGGACGGCAGGAGGAGAGGGGAG CCCCCTCTGGCTGTGTGTCACCTTGGCTGGCTGGCTGGCCAGGGTTTTGCCGATTTCCCT CCTCACATCCCTCCCACCCTCGGTCATATCATTGAGATCACCGTACCAGCAAATCTGCAA ACCAAGCACTTTGTTAATCTCCAGAGAGAGCAAATACAGCAATCTAGAGTTTAGCCTTTT TAAAAATGTGACTTTAACCCGCCCACCTGTGTCCTCCCATTGGCGTGGCATTTCTTTGGT GTCTGCTCAGAAAGAAACAGCATGGGACCGTGTGATTGGGTCCAGGCTGGGCTGTCAGGG AAGCGCCCTGGTGTCTCCGACTCATCAATTCTCGGGTCTTTTTTAAAAGCCAGGCTCCCC AAAGCACTCTGTCTCGCAATTTTGAGGAGGCTGTTCCGACCTGGAAGCGTTAAACTGCTG CATGTCATCTGGCGTCAGCTGTGAGGCTGCGCTCTGCGTGTTGTGCGTTTGCAAAATGTA TTGGCGTGACTGTAAACACATCGTTGAAGTAAAGCGATTACATATTGAGTATGTCAGCTT TTCTCACCCTCTTCTGTGCTGGGAGGAGAGTCTAACTGTAACCTTTAGGTTGTTCCAGAA AAGATTCAGGCCGTTTGGCACAGAATTGCTCTTTCTGAAGGGTAGCAGTAATGAATAGGA ACAGACAGAAAACCCCAGGAGGGGCTTTCAGGAAACTCTCCCTCTCCATCGCCATCCTGC AAGCTCCACAGCCTCGGGCTGCCAGCCTGTGGCACTGTCCTCGGTGTGTCCTGGAGCTGT GCTGGGCAGCAGGGCCTCGCGTAAGGAACTGCTGGAACCCACTGAGCCCTTCCCGGGGTT TCCCGCCGCACTCAGTGTGTTCCTTCAGGCTAGTGAGGTTTCATTCTGTTTTATTTGCAA GCTTATCAAAAGTTTGTGGAAGATACATTGTTGGGTTCCAGAGGCTGGAGTCATGCTGCC CACATCTTGTTTGGGAAAGCAAAAGCTCCCAGTGAGCTGGTGTCCCCGTGTGTCTTTCAT GGGACTGTCCCCTTTAGAGATCCCACCTGTCAGAGCCACAGCTTCGGGGTCCTGTCATCA CATCCCCTGGGAGGGGAGGCAGGAGGAGGCCGAGGGCCCCAGGATGTCTGCCTGGTCCCT TCTCACTGTGAGGACGCCCTTGGCACACCTTTCTCAAGTCACACAAATTACTGCAGTTAC ATACAGAATTGCTGACAGGAGCAGGAGACGCTGAGGGAAACAGCTGGCAATGTGACAAAA GTCTTTTCTGGGACAACAATCAAATCATGTATTTGTATTTTTTTAAGTTTACCAATGAAT TGTACAACAATGTAAAAATAAAGTTCATCCTAATATGCTGTGCACATCTTGCTTAAAAAT GTCTTCAGCACCCAGTGCAGTGATCTTTCCCTCACACACTGCATGCAGCAGGAGCCTCTT GTTTTTCTTAATGAGCTGAAAAGACAGCAGATGTTCACAGCTGATGCTGGGTGTTGACTC AGCGCCACGGGAAGCTCTGTGCCCGCAGGTAAGCACGCACAGTCTTACAGTTCTCCTTGT AAAATATCATCACCCTTCCTGCCTGAGAAACGAGTACATTTGTATTTTATGTAACAACAA TAGTCAAGGCAGCATTGCAACACTGAGCAGGGTGAGGTGGGGGTGCTGAGCACAGGACAA GAGGGAGGAGGCCTGCCCTCCATTCAGATGCATCTGCATCGCCCTTCTGTGTGCAGTCAC ATCGAGACTGCACACAGCATGCATCTCCTCTTGGAAAATATCTTTTGCCTCCGAGTTGTT TTAAGCAATTAGAATCAGGTCCTGAATCCCCAGACTGTTCAGAGACTTCAAGGGACACCT CCCTCACAAGAAGCCTGGCACCCCCACTGTGTACCTTTGAGAGGAAAGGAGTGCGTTTGT TTTCATCTGCATTCTGTTTGTCAGTGGCAACAGACTCTATCAATGTAAAACCATGGTTGT GATCATGTGGGGAAATCAAATAAATCCTTTGAAACTCTC |
Protein Sequence | >9922 : length: 1222 MASAAEPPGQAAEYLQELTRIVAAQQELLARRRRRIEELERQVARLSRENAGLLERHRRH LAACARRPDPGPGPGPQPLGAIPELGGRRDKSEGESSRSVRSSLDTGSSLSTDRYSVEGE APSSETGTSLDSPSAYPQGPLVPGSSLSPDHYEHTSVGAYGLYSGPPGQQQRTRRPKLQH STSILRKQAEEEAIKRSRSLSESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFR QYQMNKNFERLRSSMSENRMSRRIVLSNMRMQFSFEGPEKVHSSYFEGKQVSVTNDGSQL GALVSPECGDLSEPTTLKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHTE EAPALDAARARDTEPQTALHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPS STESDLRLRAGGAAPDYWALAHKEDKADTDTSCRSTPSLERQEQRLRVEHLPLLTIEPPS DSSVDLSDRSERGSLKRQSAYERSLGGQQGSPKHGPHSGAPKSLPREEPELRPRPPRPLD SHLAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYH KEARNSWDSPAFSNDVIRKRHYRIGLNLFNKKPEKGVQYLIERGFVPDTPVGVAHFLLQR KGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSTMELDEALRKFQAHIRVQGEAQKVER LIEAFSQRYCICNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFIKNL RGVDDGEDIPREMLMGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHPGLGCVL SLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSF SLYGMQVLLFENQYYPNGIRLTSSVPGADIKVLINFNAPNPQDRKKFTDDLRESIAEVQE MEKHRIESELEKQKGVVRPSMSQCSSLKKESGNGTLSRACLDDSYASGEGLKRSALSSSL RDLSEAGKRGRRSSAGSLESNVEGSIISSPHMRRRATSTRECPSRPHQTMPNSSSLLGSL FGSKRGKPPPQAHLPSAPALPPPHPPVVLPHLQHSVAGHHLGPPEGLPQAAMHGHHTQYC HMQNPPPYHHHHHHHPPQHIQHAHQYHHGPHGGHPAYGAHAHGHPPLPSAHVGHTVHHHG QPPAPPPPTSSKAKPSGISTIV |